Foods

Sesame oil

sesame oil

What is sesame oil

Sesame oil is an edible vegetable oil derived from sesame seeds (Sesamum indicum). Sesame oil is used in salad and cooking oils, shortening and some margarines. Sesame oil is a key flavor ingredient in some Chinese dishes. Sesame oil keeps well and resists rancidity, due to the presence of a natural antioxidant, sesamol. Commercially, sesame oil comes in two types. One type of sesame oil is a pale yellow liquid and has a pleasant grain-like odor and somewhat nutty taste 1. Sesame oil is high in polyunsaturated fats (PUFAs), ranking fourth behind safflower, soybean and corn oil. Sesame oil is excellent for use as frying oil, in cosmetics and in food preparations. The other type of sesame oil is amber-colored and aromatic, made from pressed and toasted sesame seeds 1. This popular ingredient in ethnic cooking is not used as a cooking oil, however, because the flavor is too intense and it burns quite easily. Instead, amber-colored sesame oil is normally added as a flavoring agent in the final stages of cooking.

Oil is extracted from sesame seeds by mechanical pressing. The sesame seed may be cold pressed to give an aromatic salad oil or hot pressed to give a lower grade product. The sesame oil yield is from 50 percent to 57 percent, depending on growing conditions and seed variety.

The outstanding characteristic of sesame oil is its long shelf life due to its natural antioxidant, sesamol. This quality makes sesame oil applicable for use in the manufacture of margarine in many parts of the world where there is inadequate refrigeration. Sesame oil is also used in paints, soaps, cosmetics, perfumes, bath oils, insecticides and pharmaceuticals (vehicle for drug delivery). Poppy seed, cotton seed and rape oils are frequently added to sesame oil.

Sesame oil is rich in both MUFA (monounsaturated fatty acid) and PUFA (polyunsaturated fatty acid). Many clinical and animal studies have identified that sesame oil contains lignans 2 and is able to reduce oxidative stress and inflammation 3. Recently, scientists revealed a close relationship of inflammation with oxidative stress 4, as well as the effects of sesame oil feeding on inflammation and atherosclerosis in vivo 5.

Sesame oil allergy

As with numerous seed and nut foods, sesame oil may produce an allergic reaction, although the incidence of this effect is rare at approximately 0.1% of the population 6, 7. Reports of sesame allergy are growing in developed countries during the 21st century, with the allergic mechanism from sesame oil exposure expressed as contact dermatitis, possibly resulting from hypersensitivity to lignin-like compounds 8.

Symptoms of an allergic or allergic-type reaction

When someone comes in contact with a food allergen or added sulphites, the symptoms of an allergic or allergic-type reaction may develop quickly and rapidly progress from mild to severe. The most severe form of an allergic reaction is called anaphylaxis. Symptoms can include breathing difficulties, a drop in blood pressure or shock, which may result in loss of consciousness and even death. A person experiencing an allergic reaction may have any combination of the following signs or symptoms:

  • Skin: hives, swelling (face, lips, tongue), itching, warmth, redness;
  • Respiratory: coughing, wheezing, shortness of breath, chest pain or tightness, throat tightness, hoarse voice, nasal congestion or hay fever-like symptoms (runny, itchy nose and watery eyes, sneezing), trouble swallowing;
  • Gastrointestinal: nausea, pain or cramps, vomiting, diarrhea;
  • Cardiovascular: paler than normal skin colour/blue skin colour, weak pulse, dizziness or light headedness, loss of consciousness, shock;
  • Other: anxiety, sense of impending doom, headache, uterine cramps, metallic taste.

I have a sesame seed allergy. How can I avoid a sesame seed-related reaction?

  • Read food labels.

Other names for sesame seeds

In the past, some products have used other names for sesame on their labels. These names are not permitted without the word sesame also appearing on the label, based on the enhanced labelling requirements for food allergens, gluten sources and added sulphites. However, if you have a sesame allergy and see one of the following in the list of ingredients on a product you should not eat it.

  • Benne, benne seed and benniseed
  • Gingelly and gingelly oil
  • Seeds
  • Sesamol and sesamolina
  • Sesamum indicum
  • Sim sim
  • Til
  • Tahini (sesame paste)

Examples of foods and products that contain or often contain sesame seeds:

  • Bread (e.g., hamburger buns, multi-grains), bread crumbs and sticks, cereals, crackers, melba toast and muesli
  • Dips and spreads, e.g., hummus, chutney
  • Combination foods, e.g., flavoured rice, noodles, shish kebabs, stews and stir fries
  • Sesame oil, sesame salt (gomasio)
  • Tahina
  • Tempeh
  • Vegetarian burgers
  • Snack bars (protein bars, granola bars)

Avoid food and products that do not have an ingredient list and read labels every time you shop.

Other possible sources of sesame:

  • Some baked goods
  • Dressings, gravies, marinades, salads, sauces and soups
  • Herbs, seasonings, flavourings and spices
  • Vegetable Pâtés
  • Snack foods, e.g., crackers, sesame snap bars, granola bars
  • Vegetable oil (may contain sesame oil)

Non-food sources of sesame seeds:

  • Adhesive bandages
  • Cosmetics, hair care products, perfumes, soaps and sunscreens
  • Drugs
  • Fungicides and insecticides
  • Lubricants, ointments and topical oils
  • Pet food
  • Sesame meal, e.g., poultry and livestock feed

Note: These lists are not complete and may change. Food and food products purchased from other countries, through mail-order or the Internet, are not always produced using the same manufacturing and labelling standards as in the US.

Avoid all food and products that contain sesame and any product whose label carries a precautionary statement warning that the product might have sesame in it such as “may contain” sesame or similar wording. When provided by a manufacturer, precautionary statements are usually found after the list of ingredients or “Contains” statement if there is one.

If sesame is part of the product formulation, it must be declared in the list of ingredients or in a separate “contains” statement immediately following the list of ingredients.

  • Avoid any products that do not have an ingredient list.
  • Read labels every time you shop. Manufacturers may occasionally change their recipes or use different ingredients for varieties of the same product.

What do I do if I am not sure whether a product contains sesame seeds?

If you have a sesame seed allergy, do not eat, drink or use the product. Obtain ingredient information from the manufacturer.

Does product size affect the likelihood of an allergic reaction?

Product size does not affect the likelihood of a reaction; however, the same brand of product may be safe to consume for one product size but not another. This is because product formulation may vary between different product sizes of the same product or be produced in a different facility. Always read the ingredient lists carefully.

Is sesame oil healthy?

Yes, sesame oil is healthy and sesame oil is goof for you, because sesame oil oil has 39.7% content of monounsaturated fats (MUFAs) and 41.7% polyunsaturated fats (PUFAs) (see Table 1 below). Monounsaturated fats can have a beneficial effect on your heart when eaten in moderation and when used to replace saturated fat and trans fat in your diet. The cholesterol-lowering effect of sesame oil could be attributed to the content of monounsaturated fats (MUFAs) and polyunsaturated fats (PUFAs) in sesame oil and sesame seeds and that part of the effect is due to the replacement of mixtures of saturated fats in the diet by monounsaturated fats and polyunsaturated fats, which are the prevalent fatty acids in sesame oil and sesame seeds. The American Heart Association recommends that for good health, the majority of the fats that you eat should be monounsaturated or polyunsaturated 9, 10. Therefore, you should eat foods containing monounsaturated fats and/or polyunsaturated fats instead of foods that contain saturated fats and/or trans fats.

Replacing bad fats (saturated and trans) with healthier fats (monounsaturated and polyunsaturated) is better for your heart.

One way you can do this is by choosing healthier nontropical vegetable oils for cooking and preparing food.

Use these oils instead of solid fats (including butter, shortening, lard and hard stick margarine) and tropical oils (including palm and coconut oil), which can have a lot of saturated fat.

Cooking and salad oils that contain more monounsaturated and polyunsaturated fats and less saturated fat:

  • Canola oil
  • Corn oil
  • Olive oil
  • Peanut oil
  • Safflower oil
  • Soybean oil
  • Sunflower oil

Blends or combinations of these oils, often sold under the name “vegetable oil,” and cooking sprays made from these oils are also good choices. Some specialty oils, like avocado, grapeseed, rice bran and sesame, can be healthy choices but may cost a bit more or be harder to find. Also to make sure you’re getting the healthier oil, always read the ingredients of the oil for added antioxidants like TBHQ (Tert-butylhydroquinone).

In general, choose oils with less than 4 grams of saturated fat per tablespoon, and no partially hydrogenated oils or trans fats.

You may find that some oils have distinctive flavors, so try different types to discover which ones you like. Also, some oils are better for certain types of cooking than others, so you may want to have more than one type in your pantry.

Figure 1. Dietary Fats and Mortality Rates

dietary fats and mortality rate

Sesame oil nutrition facts

Sesame oil has 40 calories per teaspoon.

Table 1. Sesame oil nutrition

NutrientUnitValue per 100 gteaspoon 4.5 g
Approximates
Waterg00
Energykcal88440
Proteing00
Total lipid (fat)g1004.5
Carbohydrate, by differenceg00
Fiber, total dietaryg00
Sugars, totalg00
Minerals
Calcium, Camg00
Iron, Femg00
Magnesium, Mgmg00
Phosphorus, Pmg00
Potassium, Kmg00
Sodium, Namg00
Zinc, Znmg00
Vitamins
Vitamin C, total ascorbic acidmg00
Thiaminmg00
Riboflavinmg00
Niacinmg00
Vitamin B-6mg00
Folate, DFEµg00
Vitamin B-12µg00
Vitamin A, RAEµg00
Vitamin A, IUIU00
Vitamin E (alpha-tocopherol)mg1.40.06
Vitamin D (D2 + D3)µg00
Vitamin DIU00
Vitamin K (phylloquinone)µg13.60.6
Lipids
Fatty acids, total saturatedg14.20.639
Fatty acids, total monounsaturatedg39.71.786
Fatty acids, total polyunsaturatedg41.71.877
Cholesterolmg00
Other
Caffeinemg00
[Source 11]

What are monounsaturated fats?

From a chemical standpoint, monounsaturated fats are simply fat molecules that have one unsaturated carbon bond in the molecule, this is also called a double bond. Oils that contain monounsaturated fats are typically liquid at room temperature but start to turn solid when chilled. Monounsaturated fats are found in high concentrations in olive oil, peanut oil, canola, avocados, almonds, safflower oils, hazelnuts, pecans, pumpkin seeds and sesame seeds and most nuts. Monounsaturated fats also are part of most animal fats such as fats from chicken, pork, beef, and wild game. When you dip your bread in olive oil at an Italian restaurant, you’re getting mostly monounsaturated fat. Monounsaturated fats have a single carbon-to-carbon double bond (see Figure 2 below). The result is that it has two fewer hydrogen atoms than a saturated fat and a bend at the double bond. This structure keeps monounsaturated fats liquid at room temperature. The carbon-carbon double bond found in monounsaturated or polyunsaturated fatty acids can exist in the cis or trans configuration. When the two hydrogen atoms are on opposite sides of the double bond, the configuration is called trans. When the hydrogen atoms are on the same side of the double bond, the configuration is called cis.

The discovery that monounsaturated fat could be healthful came from the Seven Countries Study during the 1960s. It revealed that people in Greece and other parts of the Mediterranean region enjoyed a low rate of heart disease despite a high-fat diet. The main fat in their diet, though, was not the saturated animal fat common in countries with higher rates of heart disease. It was olive oil, which contains mainly monounsaturated fat. This finding produced a surge of interest in olive oil and the “Mediterranean Diet” a style of eating regarded as a healthful choice today.

Although there’s no recommended daily intake of monounsaturated fats, the Institute of Medicine recommends using them as much as possible along with polyunsaturated fats to replace saturated and trans fats.

Figure 2. Monounsaturated Fatty Acids Structure

monounsaturated fatty acids structure

Figure 3. Polyunsaturated Fatty Acids Structure

polyunsaturated fatty acids structure

Which foods contain monounsaturated fats?

Most foods contain a combination of different fats.

Examples of foods high in monounsaturated fats include plant-based liquid oils such as:

  • olive oil,
  • canola oil,
  • peanut oil,
  • safflower oil and
  • sesame oil.

Other sources include avocados, peanut butter and many nuts and seeds.

How do monounsaturated fats affect my health?

Monounsaturated fats can help reduce bad cholesterol levels in your blood which can lower your risk of heart disease and stroke. They also provide nutrients to help develop and maintain your body’s cells. Oils rich in monounsaturated fats also contribute vitamin E to the diet, an antioxidant vitamin most Americans need more of.

Are monounsaturated fats better for me than saturated fats or trans fats?

Yes. While, all fats provide 9 calories per gram, monounsaturated fats and polyunsaturated fats can have a positive effect on your health, when eaten in moderation. The bad fats –saturated fats and trans fats – can negatively affect your health.

Sesame oil health benefits

Sesame oil has been shown to reduce high blood pressure and lower the amount of medication needed to control hypertension 12. Sesame oil is also capable of reducing plasma cholesterol, low-density lipoprotein (LDL) “bad” cholesterol, and triglyceride (TG) levels 13. Earlier studies of sesame oil diet-fed low-density lipoprotein receptor knockout (LDLR−/−) female mice showed that the plasma levels of total cholesterol, triglycerides, VLDL (very low density LDL) “bad” cholesterol, and LDL “bad” cholesterol were decreased, while HDL “good” cholesterol was significantly increased in these animals compared to high-fat diet-fed control animals 14. The sesame oil diet effectively prevented inflammation and atherosclerotic lesion formation in LDL-R−/− male mice 15. The ratio of saturated to unsaturated fatty acid composition in sesame oil is less 16 compared with many other oils, but the observed level of inhibition of atherosclerosis is remarkable. This extraordinary finding prompted scientists to question whether components in the sesame oil beyond simply the fatty acid composition could be responsible for the observed level of atherosclerotic inhibition.

Sesame oil contains lignans, which are known to complex cholesterol from the gut and prevent cholesterol absorption 17. The contribution of these lignans to the observed drop in plasma cholesterol is plausible. Similarly, nonsaponifiable components of sesame oil might be contributing to the prevention of cholesterol absorption. We observed a decrease in the mRNA level of CD68, a marker for monocyte/macrophages, in nonsaponifiable components of sesame oil diet-fed animals compared to high fat diet-fed animals. The decrease of CD68 in the aortic arch area containing lesions is a confirmation that the presence of foam cell-forming macrophages in nonsaponifiable components of sesame oil animals was reduced. Animal data suggest that nonsaponifiable components of sesame oil is able to inhibit atherosclerosis in animals 17.

Sesame oil uses

The outstanding characteristic of sesame oil is its long shelf life due to its natural antioxidant, sesamol. This quality makes sesame oil applicable for use in the manufacture of margarine in many parts of the world where there is inadequate refrigeration. Sesame oil is also used in paints, soaps, cosmetics, perfumes, bath oils, insecticides and pharmaceuticals (vehicle for drug delivery). Poppy seed, cotton seed and rape oils are frequently added to sesame oil.

In Ayurvedic medicine, sesame oil is used for massaging as it is believed to rid the body of heat due to its viscous nature upon rubbing 18.

In industry, sesame oil may be used as 19:

  • a solvent in injected drugs or intravenous drip solutions,
  • a cosmetics carrier oil,
  • coating stored grains to prevent weevil attacks. The oil also has synergy with some insecticides 20.

Low-grade sesame oil is used locally in soaps, paints, lubricants, and illuminants 19.

Sesame oil for cooking

Besides being used as a cooking oil in South India, sesame oil is used as a flavor enhancer in Middle Eastern, African, and Southeast Asian cuisines. Sesame oil has a distinctive nutty aroma and taste.

One type of sesame oil, a pale yellow liquid with a pleasant grain-like odor and somewhat nutty taste, is used as frying oil 19. A second type of oil, amber-colored and aromatic, is made from pressed and toasted sesame seeds and is used as a flavoring agent in the final stages of cooking 19.

Despite sesame oil’s high proportion (41%) of polyunsaturated (omega-6) fatty acids, it is least prone, among cooking oils with high smoke points, to turn rancid when kept in the open 21. This is due to the natural antioxidants, such as sesamol, present in the oil 19.

Light sesame oil has a high smoke point and is suitable for deep-frying, while dark sesame oil (from roasted sesame seeds) has a slightly lower smoke point and is unsuitable for deep-frying 19. Instead it can be used for the stir frying of meats or vegetables, sautéing, or for the making of an omelette.

Sesame oil is most popular in Asia, especially in Korea, China, and the South Indian states of Karnataka, Andhra Pradesh, and Tamil Nadu, where its widespread use is similar to that of olive oil in the Mediterranean.

  • East Asian cuisines often use roasted sesame oil for seasoning.
  • The Chinese use sesame oil in the preparation of meals.
  • In Japan, rāyu is a paste made of chili-sesame oil seasoning and used as a spicy topping on various foods, or mixed with vinegar and soy sauce and used as a dip.
  • In South India, before the advent of modern refined oils produced on a large scale, sesame oil was used traditionally for curries and gravies. It continues to be used, particularly in Tamil Nadu and Andhra Pradesh, mixed with foods that are hot and spicy as it neutralizes the heat. It is often mixed in with a special spice powder that accompanies idli and dosa as well as rice mixed with spice powders (such as paruppu podi).

Sesame oil vs olive oil

Olive oil is a key component of the Mediterranean Diet (MedDiet), being the main source of vegetable fat, especially monounsaturated fatty acids (MUFA) 22. Virgin olive oil, produced by mechanically pressing ripe olives, contains multiple bioactive and antioxidant components such as polyphenols, phytosterols and vitamin E 22, and has an acidity of <1.5%. Extra-virgin olive oil is also produced by mechanically pressing the olives but is the oil with the best quality, the most intense taste and its acidity is <1% 23. In contrast, common olive oil, obtained from a mixture of virgin and refined oil (usually more than 80% is refined), has fewer antioxidant and anti-inflammatory compounds. Since refined olive oil during the refining process loses phytochemicals, this oil is mixed with virgin olive oil to enhance the flavor, constituting the so-called common olive oil 24.

Evidence suggests that olive oil intake is inversely associated with cardiovascular disease in the Spanish general population 25 and in a cohort of Italian women 26. In the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study, total olive oil intake has been associated with a decreased risk of coronary heart disease, and also all-cause and cardiovascular mortality 27. Similarly, a lower risk of mortality was associated with regular consumption of olive oil in an Italian population after a heart attack 28 and also in an elderly population 29. A recent meta-analysis concluded that epidemiologic studies consistently found an inverse association between olive oil consumption and stroke, but there were inconsistencies between studies assessing coronary heart disease (coronary artery disease) as the end-point 30. Of note, most of the previous studies made no distinction among the different varieties of olive oil 31. Except for the European Prospective Investigation into Cancer and Nutrition-Spanish cohort that found a greater beneficial effect in coronary heart disease for the virgin olive oil variety than for the common variety 32 and similar effects for both varieties on all-cause mortality 33. This distinction is important because extra-virgin olive oil contains much higher amounts of polyphenols than common olive oil. These polyphenols may have cardiovascular benefits beyond the lipid profile. It has also been reported that olive oil intake could be beneficial in the prevention of certain cancers, such as breast cancer 34, but the evidence is weaker.

Recently, in the context of the Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts Study, it has been demonstrated that persons at high cardiovascular risk, the incidence of major cardiovascular events was lower among those assigned to a Mediterranean diet supplemented with extra-virgin olive oil or nuts than among those assigned to a reduced-fat diet 35.

Table 2. Olive oil nutrition facts

NutrientUnitValue per 100 gteaspoon 4.5 g
Approximates
Waterg00
Energykcal88440
Proteing00
Total lipid (fat)g1004.5
Carbohydrate, by differenceg00
Fiber, total dietaryg00
Sugars, totalg00
Minerals
Calcium, Camg10
Iron, Femg0.560.03
Magnesium, Mgmg00
Phosphorus, Pmg00
Potassium, Kmg10
Sodium, Namg20
Zinc, Znmg00
Vitamins
Vitamin C, total ascorbic acidmg00
Thiaminmg00
Riboflavinmg00
Niacinmg00
Vitamin B-6mg00
Folate, DFEµg00
Vitamin B-12µg00
Vitamin A, RAEµg00
Vitamin A, IUIU00
Vitamin E (alpha-tocopherol)mg14.350.65
Vitamin D (D2 + D3)µg00
Vitamin DIU00
Vitamin K (phylloquinone)µg60.22.7
Lipids
Fatty acids, total saturatedg13.8080.621
Fatty acids, total monounsaturatedg72.9613.283
Fatty acids, total polyunsaturatedg10.5230.474
Cholesterolmg00
Other
Caffeinemg00
[Source 11]
  1. Sesame Profile. https://www.agmrc.org/commodities-products/grains-oilseeds/sesame-profile/[][]
  2. Egbekun MK, Ehieze MU: Proximate composition and functional properties of full fat and defatted beniseed (Sesamum indicum L.) flour. Plant Foods Hum Nutr 1997;51:35–41[]
  3. Hou RC, Chen HL, Tzen JT, Jeng KC: Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells. Neuroreport 2003;14:1815–1819[]
  4. Aluganti Narasimhulu C, Jiang X, Yang Z, Selvarajan K, and Parthasarathy S: Is there a connection between oxidative stress and inflammation? Chronic Inflammation Molecular Pathophysiology, Nutritional and Therapeutic Interventions. (Roy S, editor; , Bagchi D, editor; , Raichaudhury S, editor. , eds.) CRC Press, Taylor and Francis, Boca Raton, FL, 2012, pp.138–152[]
  5. Aluganti Narasimhulu C, Selvarajan K, Litvinov D, Parthasarathy S: Anti-atherosclerotic and anti-inflammatory actions of sesame oil. J Med Food 2015;18:11–20 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281857/[]
  6. Sesame seed food allergy. Curr Allergy Asthma Rep. 2012 Aug;12(4):339-45. doi: 10.1007/s11882-012-0267-2. https://www.ncbi.nlm.nih.gov/pubmed/22610362[]
  7. Sesame – A priority food allergen. https://www.canada.ca/en/health-canada/services/food-nutrition/reports-publications/food-safety/sesame-priority-food-allergen.html[]
  8. Sesame allergy: a growing food allergy of global proportions? Ann Allergy Asthma Immunol. 2005 Jul;95(1):4-11; quiz 11-3, 44. https://www.ncbi.nlm.nih.gov/pubmed/16095135[]
  9. Advisory: Replacing saturated fat with healthier fat could lower cardiovascular risks. http://www.heart.org/en/news/2018/07/17/advisory-replacing-saturated-fat-with-healthier-fat-could-lower-cardiovascular-risks[]
  10. Healthy Cooking Oils. http://www.heart.org/en/healthy-living/healthy-eating/eat-smart/fats/healthy-cooking-oils[]
  11. United States Department of Agriculture Agricultural Research Service. USDA Branded Food Products Database. https://ndb.nal.usda.gov/ndb/search/list[][]
  12. Stemme S, Faber B, Holm J, Wiklund O, Witztum JL, Hansson GK: T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci U S A 1995;92:3893–3897[]
  13. Kok T, et al. : Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse. Gastroenterology 2003;124:160–171[]
  14. Narasimhulu CA, Selvarajan K, Litvinov D, Parthasarathy S. Anti-Atherosclerotic and Anti-Inflammatory Actions of Sesame Oil. Journal of Medicinal Food. 2015;18(1):11-20. doi:10.1089/jmf.2014.0138. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281857/[]
  15. Aluganti Narasimhulu C, Selvarajan K, Litvinov D, Parthasarathy S: Anti-atherosclerotic and anti-inflammatory actions of sesame oil. J Med Food 2015;18:11–20[]
  16. Selvarajan K, Aluganti Narasimhulu C, Bapputty R, Parthasarathy S: Anti-inflammatory and antioxidant activities of the nonlipid (aqueous) components of sesame oil: Potential use in atherosclerosis. J Med Food 2015;18:393–402[]
  17. Narasimhulu CA, Selvarajan K, Burge KY, Litvinov D, Sengupta B, Parthasarathy S. Water-Soluble Components of Sesame Oil Reduce Inflammation and Atherosclerosis. Journal of Medicinal Food. 2016;19(7):629-637. doi:10.1089/jmf.2015.0154. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948257/[][]
  18. Lahorkar P, Ramitha K, Bansal V, Anantha Narayana DB. A Comparative Evaluation of Medicated Oils Prepared Using Ayurvedic and Modified Processes. Indian Journal of Pharmaceutical Sciences. 2009;71(6):656-662. doi:10.4103/0250-474X.59548. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846471/[]
  19. Sesame Profile. https://www.agmrc.org/commodities-products/grains-oilseeds/sesame-profile[][][][][][]
  20. Food, Industrial, Nutraceutical, and Pharmaceutical Uses of Sesame Genetic Resources. https://hort.purdue.edu/newcrop/ncnu02/v5-153.html[]
  21. Sesame. https://hort.purdue.edu/newcrop/afcm/sesame.html[]
  22. Covas M-I. Olive oil and the cardiovascular system. Pharmacol Res. 2007;55:175–186. doi: 10.1016/j.phrs.2007.01.010[][]
  23. Guasch-Ferré M, Hu FB, Martínez-González MA, et al. Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study. BMC Medicine. 2014;12:78. doi:10.1186/1741-7015-12-78. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030221/[]
  24. Ros E. Olive oil and CVD: accruing evidence of a protective effect. Br J Nutr. 2012;108:1931–1933. doi: 10.1017/S0007114512003844[]
  25. Covas MI, Konstantinidou V, Fito M. Olive oil and cardiovascular health. J Cardiovasc Pharmacol. 2009;54:477–482. doi: 10.1097/FJC.0b013e3181c5e7fd https://www.ncbi.nlm.nih.gov/pubmed/19858733[]
  26. Bendinelli B, Masala G, Saieva C, Salvini S, Calonico C, Sacerdote C, Agnoli C, Grioni S, Frasca G, Mattiello A, Chiodini P, Tumino R, Vineis P, Palli D, Panico S. Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study. Am J Clin Nutr. 2011;93:275–283. doi: 10.3945/ajcn.110.000521 https://www.ncbi.nlm.nih.gov/pubmed/21177799[]
  27. Buckland G, Travier N, Barricarte A, Ardanaz E, Moreno-Iribas C, Sanchez M-J, Molina-Montes E, Chirlaque MD, Huerta JM, Navarro C, Redondo ML, Amiano P, Dorronsoro M, Larranaga N, Gonzalez CA. Olive oil intake and CHD in the European Prospective Investigation into Cancer and Nutrition Spanish cohort. Br J Nutr. 2012;108:2075–2082. doi: 10.1017/S000711451200298X https://www.ncbi.nlm.nih.gov/pubmed/23006416[]
  28. Barzi F, Woodward M, Marfisi RM, Tavazzi L, Valagussa F, Marchioli R. Mediterranean diet and all-causes mortality after myocardial infarction: results from the GISSI-Prevenzione trial. Eur J Clin Nutr. 2003;57:604–611. doi: 10.1038/sj.ejcn.1601575 https://www.ncbi.nlm.nih.gov/pubmed/12700623[]
  29. Masala G, Ceroti M, Pala V, Krogh V, Vineis P, Sacerdote C, Saieva C, Salvini S, Sieri S, Berrino F, Panico S, Mattiello A, Tumino R, Giurdanella MC, Bamia C, Trichopoulou A, Riboli E, Palli D. A dietary pattern rich in olive oil and raw vegetables is associated with lower mortality in Italian elderly subjects. Br J Nutr. 2007;98:406–415. doi: 10.1017/S0007114507704981[]
  30. Martínez-González MA, Domínguez L, Delgado-Rodríguez M. Olive oil consumption and risk of CHD and/or stroke: a meta-analysis of case–control, cohort and intervention studies. Br J Nutr. 2014;28:1–12. https://www.ncbi.nlm.nih.gov/pubmed/24775425[]
  31. Bendinelli B, Masala G, Saieva C, Salvini S, Calonico C, Sacerdote C, Agnoli C, Grioni S, Frasca G, Mattiello A, Chiodini P, Tumino R, Vineis P, Palli D, Panico S. Fruit, vegetables, and olive oil and risk of coronary heart disease in Italian women: the EPICOR Study. Am J Clin Nutr. 2011;93:275–283. doi: 10.3945/ajcn.110.000521[]
  32. Buckland G, Travier N, Barricarte A, Ardanaz E, Moreno-Iribas C, Sanchez M-J, Molina-Montes E, Chirlaque MD, Huerta JM, Navarro C, Redondo ML, Amiano P, Dorronsoro M, Larranaga N, Gonzalez CA. Olive oil intake and CHD in the European Prospective Investigation into Cancer and Nutrition Spanish cohort. Br J Nutr. 2012;108:2075–2082. doi: 10.1017/S000711451200298X[]
  33. Buckland G, Mayen AL, Agudo A, Travier N, Navarro C, Huerta JM, Chirlaque MD, Barricarte A, Ardanaz E, Moreno-Iribas C, Marin P, Quiros JR, Redondo M-L, Amiano P, Dorronsoro M, Arriola L, Molina E, Sanchez M-J, Gonzalez CA. Olive oil intake and mortality within the Spanish population (EPIC-Spain) Am J Clin Nutr. 2012;96:142–149. doi: 10.3945/ajcn.111.024216[]
  34. Pelucchi C, Bosetti C, Negri E, Lipworth L, La Vecchia C. Olive oil and cancer risk: an update of epidemiological findings through 2010. Curr Pharm Des. 2011;17:805–812. doi: 10.2174/138161211795428920 https://www.ncbi.nlm.nih.gov/pubmed/21443483[]
  35. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med. 2018 Jun 21;378(25):e34. doi: 10.1056/NEJMoa1800389. Epub 2018 Jun 13. https://www.nejm.org/doi/10.1056/NEJMoa1800389[]
read more

Is peanut oil healthy

peanut oil

Is peanut oil healthy?

The short answer is yes, peanut oil good for you because peanut oil has 43% content of monounsaturated fats (MUFAs) and 35% polyunsaturated fats (PUFAs) (see Table 1 below). Monounsaturated fats can have a beneficial effect on your heart when eaten in moderation and when used to replace saturated fat and trans fat in your diet. The cholesterol-lowering effect of peanut oil (and peanuts) could be attributed to the content of monounsaturated fats (MUFAs) and polyunsaturated fats (PUFAs) in peanut oil and peanuts and that part of the effect is due to the replacement of mixtures of saturated fats in the diet by monounsaturated fats and polyunsaturated fats, which are the prevalent fatty acids in peanut oil and peanuts. The American Heart Association recommends that for good health, the majority of the fats that you eat should be monounsaturated or polyunsaturated 1, 2. Therefore, you should eat foods containing monounsaturated fats and/or polyunsaturated fats instead of foods that contain saturated fats and/or trans fats.

Replacing bad fats (saturated and trans) with healthier fats (monounsaturated and polyunsaturated) is better for your heart.

One way you can do this is by choosing healthier nontropical vegetable oils for cooking and preparing food.

Use these oils instead of solid fats (including butter, shortening, lard and hard stick margarine) and tropical oils (including palm and coconut oil), which can have a lot of saturated fat.

Cooking oils that contain more monounsaturated and polyunsaturated fats and less saturated fat:

  • Canola oil
  • Corn oil
  • Olive oil
  • Peanut oil
  • Safflower oil
  • Soybean oil
  • Sunflower oil

Blends or combinations of these oils, often sold under the name “vegetable oil,” and cooking sprays made from these oils are also good choices. Some specialty oils, like avocado, grapeseed, rice bran and sesame, can be healthy choices but may cost a bit more or be harder to find. Also to make sure you’re getting the healthier oil, always read the ingredients of the oil for added antioxidants like TBHQ (Tert-butylhydroquinone).

In general, choose oils with less than 4 grams of saturated fat per tablespoon, and no partially hydrogenated oils or trans fats.

You may find that some oils have distinctive flavors, so try different types to discover which ones you like. Also, some oils are better for certain types of cooking than others, so you may want to have more than one type in your pantry.

Figure 1. Dietary Fats and Mortality Rates

dietary fats and mortality rate

What are monounsaturated fats?

From a chemical standpoint, monounsaturated fats are simply fat molecules that have one unsaturated carbon bond in the molecule, this is also called a double bond. Oils that contain monounsaturated fats are typically liquid at room temperature but start to turn solid when chilled. Monounsaturated fats are found in high concentrations in olive oil, peanut oil, canola, avocados, almonds, safflower oils, hazelnuts, pecans, pumpkin seeds and sesame seeds and most nuts. Monounsaturated fats also are part of most animal fats such as fats from chicken, pork, beef, and wild game. When you dip your bread in olive oil at an Italian restaurant, you’re getting mostly monounsaturated fat. Monounsaturated fats have a single carbon-to-carbon double bond (see Figure 2 below). The result is that it has two fewer hydrogen atoms than a saturated fat and a bend at the double bond. This structure keeps monounsaturated fats liquid at room temperature. The carbon-carbon double bond found in monounsaturated or polyunsaturated fatty acids can exist in the cis or trans configuration. When the two hydrogen atoms are on opposite sides of the double bond, the configuration is called trans. When the hydrogen atoms are on the same side of the double bond, the configuration is called cis.

The discovery that monounsaturated fat could be healthful came from the Seven Countries Study during the 1960s. It revealed that people in Greece and other parts of the Mediterranean region enjoyed a low rate of heart disease despite a high-fat diet. The main fat in their diet, though, was not the saturated animal fat common in countries with higher rates of heart disease. It was olive oil, which contains mainly monounsaturated fat. This finding produced a surge of interest in olive oil and the “Mediterranean Diet” a style of eating regarded as a healthful choice today.

Although there’s no recommended daily intake of monounsaturated fats, the Institute of Medicine recommends using them as much as possible along with polyunsaturated fats to replace saturated and trans fats.

Figure 2. Monounsaturated Fatty Acids Structure

monounsaturated fatty acids structure

Figure 3. Polyunsaturated Fatty Acids Structure

polyunsaturated fatty acids structure

Which foods contain monounsaturated fats?

Most foods contain a combination of different fats.

Examples of foods high in monounsaturated fats include plant-based liquid oils such as:

  • olive oil,
  • canola oil,
  • peanut oil,
  • safflower oil and
  • sesame oil.

Other sources include avocados, peanut butter and many nuts and seeds.

How do monounsaturated fats affect my health?

Monounsaturated fats can help reduce bad cholesterol levels in your blood which can lower your risk of heart disease and stroke. They also provide nutrients to help develop and maintain your body’s cells. Oils rich in monounsaturated fats also contribute vitamin E to the diet, an antioxidant vitamin most Americans need more of.

Are monounsaturated fats better for me than saturated fats or trans fats?

Yes. While, all fats provide 9 calories per gram, monounsaturated fats and polyunsaturated fats can have a positive effect on your health, when eaten in moderation. The bad fats –saturated fats and trans fats – can negatively affect your health.

Peanut allergy peanut oil

Peanut allergy is the most common cause of deaths related to food allergy. Peanut oil is often suspected of causing reactions to meals in which a more obvious source of peanut cannot be found.

Refined peanut oil is odorless and flavorless and is commonly used in catering. Crude peanut oil, which is known to contain considerable amounts of protein is used only rarely, when a peanut flavor is deliberately required.

In vivo challenges of 60 subjects with proved peanut allergy showed no reaction to refined peanut oil, but six (10%) reacted to the crude peanut oil 3.

If refined peanut oil is used properly and is not reused after cooking peanuts, it seems to be safe for most people with peanut allergy; crude oil represents a risk 3.

Crude peanut oil caused allergic reactions in 10% of allergic subjects studied and should continue to be avoided. Refined peanut oil did not pose a risk to any of the subjects. It would be reasonable to recommend a change in labeling to distinguish refined from crude peanut oil. The confusing use of the term peanut oil should be stopped, and food labeling should distinguish between refined and crude peanut oils.

Peanut oil ingestion does not pose a risk to peanut-sensitive individuals 4. Ten peanut-sensitive patients were enrolled in a double-blind crossover trial to determine whether ingestion of peanut oil can induce adverse reactions in such individuals 4. All patients had experienced prior allergic reactions to peanut ingestion, including any of the following: generalized urticaria, angioedema, abdominal cramps, vomiting, diarrhea, bronchospasm, or shock. All patients had elevated levels of serum IgE antibodies to both crude peanut extract and the purified peanut allergen, Peanut-I, by RAST assay; binding values ranged from 2 to 26 times that of negative control serum. All patients demonstrated negative puncture skin tests to both peanut oil and olive oil (control). At 30-min intervals, patients ingested 1, 2, and 5 ml of either oil contained in 1 ml capsules while under constant observation. These quantities exceed the maximum estimated dose of peanut oil that would occur in single meals. Patients returned 2 wk later for ingestion challenge with the remaining oil. No untoward reactions were observed with either peanut oil or olive oil.

The results of this double-blind crossover trial clearly indicate that peanut oil is not allergenic to peanut-sensitive individuals 4. Individuals with peanut hypersensitivity do not need to eliminate peanut oil from their diets 4. In managing the peanut-sensitive individual, usual and reasonable advice has been to avoid peanuts and other potential sources of the allergen. This warning has commonly included an avoidance of peanut oil. However, based on the results of this study, it is not necessary to eliminate or restrict the use of peanut oil by peanut-sensitive individuals. Undue restriction of the allergic patient’s diet is not only confusing to the patient but also raises unwarranted and unnecessary anxiety.

Peanut oil bottom line

  • Most health professionals agree that refined peanut oil is unlikely to be a problem for people with peanut allergy, because almost all the proteins that cause allergic reactions are likely to be removed during the manufacturing process. However, refined peanut oil is still covered by food labeling rules and so it will be listed as ‘peanut oil’ when used in pre-packed foods.
  • Cold-pressed, or unrefined/unprocessed (crude) peanut oil can contain peanut proteins, which can cause a reaction in people who are sensitive. Remember that peanut oil is often called ‘groundnut oil’.

Does peanut oil elicit an allergic reaction?

If refined peanut oil is used properly and is not reused after cooking peanuts, it seems to be safe for most people with peanut allergy; crude oil, however, represents a risk. Cold pressed, expelled or extruded peanut oil is NOT safe for peanut allergic individuals.

Peanut oil nutrition

Monounsaturated fats – like all fats – contain 9 calories per gram.

Table 1. Peanut oil nutrition facts

NutrientUnitTbsp 14 g Value per 100 g
Approximates
Energykcal120857
Proteing00
Total lipid (fat)g14100
Carbohydrate, by differenceg00
Minerals
Sodium, Namg00
Lipids
Fatty acids, total saturatedg2.517.86
Fatty acids, total monounsaturatedg642.86
Fatty acids, total polyunsaturatedg4.99935.71
Fatty acids, total transg00
Cholesterolmg00
[Source 5]

Peanut oil vs Canola oil

Table 2. Canola oil nutrition facts

NutrientUnitTbsp 14 g Value per 100 g
Approximates
Energykcal120857
Proteing00
Total lipid (fat)g14100
Carbohydrate, by differenceg00
Minerals
Sodium, Namg00
Lipids
Fatty acids, total saturatedg17.14
Fatty acids, total monounsaturatedg9.00164.29
Fatty acids, total polyunsaturatedg428.57
Fatty acids, total transg00
Cholesterolmg00
[Source 5]

Peanut oil vs Vegetable oil

Table 3. Vegetable oil (soybean oil) nutrition facts

NutrientUnitTbsp 14 g Value per 100 g
Approximates
Energykcal120857
Proteing00
Total lipid (fat)g14100
Carbohydrate, by differenceg00
Fiber, total dietaryg00
Sugars, totalg00
Minerals
Calcium, Camg00
Iron, Femg00
Sodium, Namg00
Vitamins
Vitamin C, total ascorbic acidmg00
Vitamin A, IUIU00
Lipids
Fatty acids, total saturatedg2.00114.29
Fatty acids, total monounsaturatedg321.43
Fatty acids, total polyunsaturatedg857.14
Fatty acids, total transg00
Cholesterolmg00
[Source 5]

Cooking with peanut oil

You can usually use peanut oil just like solid cooking fats. For example, use peanut oil to:

  • Make your own salad dressings, marinades, dips and sauces.
  • Grill, sauté, stir fry, bake or roast foods.
  • Coat pans to keep food from sticking.
  • Spread or drizzle on foods for flavor.
  • “Season” cast-iron cookware.
  • Substitute for butter, margarine or solid fats in recipes.
  1. Advisory: Replacing saturated fat with healthier fat could lower cardiovascular risks. http://www.heart.org/en/news/2018/07/17/advisory-replacing-saturated-fat-with-healthier-fat-could-lower-cardiovascular-risks[]
  2. Healthy Cooking Oils. http://www.heart.org/en/healthy-living/healthy-eating/eat-smart/fats/healthy-cooking-oils[]
  3. Randomised, double blind, crossover challenge study of allergenicity of peanut oils in subjects allergic to peanuts. BMJ 1997;314:1084[][]
  4. Peanut oil is not allergenic to peanut-sensitive individuals. J Allergy Clin Immunol. 1981 Nov;68(5):372-5. https://www.jacionline.org/article/0091-6749(81)90135-4/pdf[][][][]
  5. United States Department of Agriculture Agricultural Research Service. USDA Branded Food Products Database. https://ndb.nal.usda.gov/ndb/search/list[][][]
read more

Is kimchi good for you?

kimchi

What is kimchi

Kimchi is a traditional fermented vegetable, a staple in Korean cuisine and is an indispensable side dish of every meal in Korea 1. Moreover, the annual tradition Gimjang involves preparing and storing a large quantity of kimchi for the winter season 2. There are about 187 kinds of Kimchi according to the ingredients and processing methods 3. Kimchi is prepared by various ingredients, such as Chinese cabbage (Brassica pekinensis Rupr.), processed with seasoning mixture mainly consisting of red pepper (Capsicum annuum L.) powder, garlic, ginger, edible Allium varieties other than garlic, and radish in the presence of salt. These ingredients may be chopped, sliced and broken into pieces 4. Kimchi is then fermented in brine before or after being packaged into appropriate containers to ensure the proper ripening and preservation of the product by lactic acid production at low temperatures. The drained weight of the final product, as a percentage of the indicated weight, should be not less than 80% by weight, calculated on the basis of the weight of distilled water at 20 °C which the sealed container will hold when completely filled. The drained weight of the final product as a percentage by the indicated weight shall not be less than 80% by weight. Kimchi is currently recognized worldwide as a nutritious and healthy food 5.

Traditional kimchi that is fermented naturally at low temperatures without any starter is a complex system, with dynamic biological and biochemical changes during fermentation 6. Because kimchi fermentation is accomplished by a succession of naturally occurring different lactic acid bacteria, fermentative metabolic features of microbial communities during kimchi fermentation process are different every time, which makes it difficult to consistently produce standardized kimchi with high quality 6. Until now, rational and systematic approaches to control kimchi fermentation for the production of kimchi with uniform quality have not been developed because the understanding of kimchi microbial communities during fermentation has not yet been accomplished 6. Therefore, comprehensive investigation on the fermentative metabolic features of kimchi lactic acid bacteria during fermentation is indispensable to control kimchi fermentation 7. With metatranscriptomic analysis, it is relatively easy to investigate the metabolic features of microbial communities in fermented foods such as kimchi, because these communities are not so complex as those in other natural environments. Therefore, a transcriptomic analysis was performed to examine the metabolic features of Leuconostoc mesenteroides during kimchi fermentation. Relative abundances (%) of mRNA sequencing reads mapped to the genomes of Leuconostoc mesenteroides strains for total lactic acid bacteria mRNA sequencing reads during the kimchi fermentation were calculated. The relative abundances were high at the early kimchi fermentation period and decreased to the lowest value at 18 days as the fermentation progressed, suggesting that members of Leuconostoc mesenteroides are more responsible for kimchi fermentation during the early fermentation period. The metabolic properties of Leuconostoc mesenteroides during kimchi fermentation were investigated by metabolic mapping of the Leuconostoc mesenteroides mRNA sequencing. The transcriptomic analysis showed that genes associated with carbohydrate metabolisms, nucleotide metabolism, fatty acid biosynthesis, oxidative phosphorylation, riboflavin metabolism, and glutamine and glutamate metabolism were highly expressed during kimchi fermentation 6. Genes associated with fatty acid biosynthesis, nucleotide metabolism, and amino acid metabolism, probably more related to cell growth, were up-regulated in Leuconostoc mesenteroides during the early kimchi fermentation period, which may explain why Leuconostoc mesenteroides is more abundant at that stage. Conversely, genes associated with oxidative phosphorylation, biosynthesis of other secondary metabolisms, and glutamine and glutamate metabolism were up-regulated during the late kimchi fermentation period 6. Genes associated with the biosynthesis of riboflavin were highly expressed during the entire kimchi fermentation, suggesting that Leuconostoc mesenteroides may be an important producer of riboflavin during the kimchi fermentation 6.

Leuconostoc mesenteroides (Leu. mesenteroides) comprises Gram-positive, catalase-negative, facultatively anaerobic, non-spore-forming, and spherical heterofermentative and mostly dextran-producing lactic acid bacteria (LAB), with coccus shapes and relatively low G + C contents 8. Leuconostoc mesenteroides members are reported to be mainly responsible for the fermentation of various vegetables, such as kimchi and sauerkraut (pickled cabbage), under low temperature and moderate salinity conditions, although some Leuconostoc mesenteroides strains have been isolated from dairy products such as cheese 8. In particular, Leuconostoc mesenteroides strains were found to be the major lactic acid bacteria, along with Lactobacillus sakei and Weissella koreensis, present during kimchi fermentation, suggesting that they are well adapted to kimchi fermentation conditions 7. Moreover, because Leuconostoc mesenteroides strains produce mannitol, a compound with antidiabetic and anticarcinogenic properties known for imparting a refreshing taste, and bacteriocins during fermentation and have some health improving effects 9, they have been considered as starter cultures for kimchi fermentation or potential probiotics in industries 10.

Although Leuconostoc mesenteroides strains are generally considered to be non-infectious agents in humans, there have been some clinical reports that Leuconostoc mesenteroides might be associated with certain human diseases such as brain abscess, endocarditis, nosocomial outbreaks, and central nervous system tuberculosis 11. In addition, there is a report that Leuconostoc mesenteroides can cause spoilage in some types of food products 12. These reports suggest that further studies on the physiological and fermentative properties of Leuconostoc mesenteroides strains are needed to vouch for the safety and quality of kimchi and sauerkraut products fermented with Leuconostoc mesenteroides 6.

Figure 1. Kimchi

kimchi

Kimchi nutrition

Nutritionally, Kimchi is a low-calorie food (15 kcal/100 g) and an important source of vitamins, minerals, and fiber 13. It is also a good source of phytochemicals (e.g., β-sitosterol, glucosinolates, isothiocyanate, indoles, allyl compounds) and probiotic strains (e.g., Lactobacillus plantarum, Lactobacillus brevis, Leuconostoc mesenteroides) 14. In regard to these nutrition properties, many functional properties of Kimchi have been reported including anti-oxidative activity 15, anti-mutagenic and anti-tumor activities 16, anti-atherogenic activity 17 and weight-controlling activity 18.

Table 1. Kimchi nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg94.3
Energykcal15
EnergykJ65
Proteing1.1
Total lipid (fat)g0.5
Ashg1.7
Carbohydrate, by differenceg2.4
Fiber, total dietaryg1.6
Sugars, totalg1.06
Minerals
Calcium, Camg33
Iron, Femg2.5
Magnesium, Mgmg14
Phosphorus, Pmg24
Potassium, Kmg151
Sodium, Namg498
Zinc, Znmg0.22
Copper, Cumg0.024
Selenium, Seµg0.5
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.01
Riboflavinmg0.21
Niacinmg1.1
Vitamin B-6mg0.213
Folate, totalµg52
Folic acidµg0
Folate, foodµg52
Folate, DFEµg52
Choline, totalmg15.5
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg5
Retinolµg0
Carotene, betaµg55
Carotene, alphaµg1
Cryptoxanthin, betaµg0
Vitamin A, IUIU93
Lycopeneµg0
Lutein + zeaxanthinµg49
Vitamin E (alpha-tocopherol)mg0.11
Vitamin E, addedmg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg43.6
Lipids
Fatty acids, total saturatedg0.067
04:00:00g0
06:00:00g0
08:00:00g0
10:00:00g0
12:00:00g0.003
14:00:00g0.003
16:00:00g0.057
18:00:00g0.003
Fatty acids, total monounsaturatedg0.037
16:1 undifferentiatedg0
18:1 undifferentiatedg0.037
20:01:00g0
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg0.241
18:2 undifferentiatedg0.104
18:3 undifferentiatedg0.137
18:04:00g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Cholesterolmg0
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
[Source: United States Department of Agriculture Agricultural Research Service 19]

Kimchi health benefits

In Korea, where the aging of population is rapidly increasing and westernized lifestyle is becoming more prevalent, cardiovascular disease and metabolic syndrome–related diseases such as type two diabetes mellitus are becoming important public health issues. In fact, during the last two decades, crude mortality from ischemic heart disease dramatically increased for men (10.3-fold increase), and women (17.5-fold increase), and diabetes-related mortality was also increased four times for men and six times for women 20. These tendencies are shown throughout the world. Therefore, many trials to prevent or decrease the prevalence of these degenerative diseases have been performed with modification of environmental factors such as dietary patterns and screening for biologically effective compounds from foods.

Many studies have reported the beneficial effects of kimchi, including its anti-oxidative activity 21, 22, anti-obesity 23, anti-asthma 24, anti-aging effects 25, anti-cancer and antimutagenic activities 26, 27, anti-atherosclerotic 28 and cholesterol- lowering effects 29 and antimicrobial activity 30, immune stimulatory activity 31, weight reduction and lipid lowering effects 32 and anti-atherogenic activity 33.

Numerous studies have reported on the lipid-lowering mechanisms of kimchi or its ingredients such as Chinese cabbage, hot red pepper, garlic, green leek, and ginger 20. β-sitosterol in Chinese cabbage, S-methlycysteinsulfoxide and S-allylcysteinsulfoxide in garlic, capsaicin in red pepper are known bioactive compounds present in kimchi ingredients responsible for lowering blood lipids 34. β-Sitosterol, a phyto-cholesterol, competes with dietary cholesterol in the intestine for absorption 35. Sulfur compounds in onion and garlic stimulate lipolysis by elevating the hormone secretion such as adrenalin and glucagon, or suppressing enzyme activities responsible for cholesterol synthesis. Acetyl-CoA synthetase and/or 3-hydroxy-3-methyl-glutaryl CoA reductase activity was inhibited by allin or allicine 34. Capsaicin stimulates the secretion of plasma cholesterol to extra-circulation as bile via elevating 7α-hydroxylase activity 36. It also increases energy expenditure by regulating thyroid hormone secretion 37. Additionally, lactic acid bacteria produced during the fermentation of kimchi are believed to contribute to the cholesterol lowering activity. Lactobacillus acidophilus usually detected in kimchi can bind the cholesterol in their cell wall besides decomposing the cholesterol for assimilation and de-conjugates the bile acids 38. In previous study, kimchi effectively attenuated plasma cholesterol levels in rats and rabbits fed high cholesterol diets 39. In addition, hypercholesterolemic rabbits administered bioactive compound of kimchi, 3-(4′-hydroxyl-3′,5′-dimethoxyphenyl)propionic acid (HDMPPA) showed a drop in plasma cholesterol and LDL “bad” cholesterol within 4 days of treatment 40. These results supported the findings that kimchi supplementation to young adults for a short period could alleviate serum cholesterol concentration 41. In another study 41, kimchi consumption significantly lowered the fasting blood glucose concentration according to amount of kimchi intake. There are several considerations about the lowering effect of kimchi on fasting blood glucose. Compared with energy and carbohydrate intake between pre- and post-test, these two factors showed no difference in the two groups. Furthermore, in a previous questionnaire for physical activity, 36% and 27% subjects in the low and high group answered “no extra exercise”, respectively. These data suggested that a relatively greater reduction of fasting blood glucose or plasma lipids in the high group could be related with intake of kimchi 41.

Focusing on the effect of fermentation, this study 42 hypothesized that consumption of fermented kimchi would have more beneficial effects compared with that of fresh kimchi on metabolic parameters that are related to cardiovascular disease and metabolic syndrome risks in overweight and obese subjects. Twenty-two overweight and obese patients with body mass indexes greater than 25 kg/m² were randomly assigned to two 4-week diet phases separated by a 2-week washout period (crossover design). During each diet phase, the subjects consumed either fresh or fermented kimchi. Anthropometric data showed significant decreases in body weight, body mass index, and body fat in both groups, and the fermented kimchi group showed a significant decrease in the waist-hip ratio and fasting blood glucose. Net differences in the systolic blood pressure, diastolic blood pressure, percent body fat, fasting glucose, and total cholesterol in the fermented kimchi group were significantly greater than those in the fresh kimchi group. There was also a tendency for a decrease in fasting insulin after consumption of fermented kimchi. Therefore, the ingestion of fermented kimchi had positive effects on various factors associated with metabolic syndrome, including systolic and diastolic blood pressures, percent body fat, fasting glucose, and total cholesterol, compared with the fresh kimchi. These results suggest that the maturity of kimchi (fresh vs fermented) may affect obesity, lipid metabolism, and inflammatory processes 42.

Chinese cabbage, a main ingredient of Kimchi, is rich in minerals, vitamin C, dietary fibers, and especially phytochemicals 43. Also, cabbage contains several organic sulfur compounds, such as isothiocyanates and dithiolethiones. In a previous study 44, these organic sulfur compounds were shown to exert diverse biological effects including the inhibition of tumor cell proliferation, antimicrobial effects, and free radical scavenging. Another ingredient, garlic, contains various sulfur-contained compounds; S-allyl-l-cysteine, S-allyl-l-cysteine sulfoxides and alliin 45. It suppress the production of inflammatory cytokines, such as TNF-a, IL-1, IL-6, and interferon-γ 46. Red pepper contains high levels (25-80 mg%) of capsaicin. Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is involved in physiological functions related to immune response 47.

In a previous study, 3-(4′-hydroxyl-3′,5′-dimethoxyphenyl)propionic acid (HDMPPA), an active principle in cabbage kimchi 48, demonstrated anti-atherogenic activity in terms of preventing the fatty streak formation or atherosclerosis in rabbits 49. Among the possible mechanisms, it was suggested that HDMPPA suppressed transcription rate for the enzymes responsible for the production of reactive oxygen species and also inhibited adhesion molecule expression whereas endothelial nitric oxide synthase activity in the aorta was elevated 50. In a human study, kimchi consumption exerted favorable plasma lipid lowering effects and improved metabolic syndrome parameters in obese people 51.

Probiotics are living micro-organisms that have a health benefit for their host. Orally ingested probiotic bacteria are able to modulate the immune system; however, differences exist in the immunomodulatory effects of different probiotic strains 52. Especially, lactic acid bacteria produced during the fermentation process from Kimchi : Leuconostoc mesenteroides, Leuconostoc citreum, Leuconostoc gasicomitatum, Leuconostoc kimchii, Leuconostoc inhae, Weissella Koreensis, Weissella cibaria, Lactobacillus plantarum, Lactobacillus sakei, Lactobacillus delbrueckii, Lactobacillus buchneri, Lactobacillus brevis, Lactobacillus fermentum, Pediococcus acidilactici and Pediococcus Pentosaceus 53.

According to the Lee et al. 54, suppressor T lymphocyte cells and Natural killer cells are increased with Lactobacillus casei and Bifidobacterium longumi treatment. However, another study 55, T-helper cells and suppressor T cells were not affected by the consumption of Kimchi. T lymphocyte cells play central roles in the immune system, in which their major function assisting B lymphocyte cells in the production of antibodies. Serum Ig (immunoglobulin) levels are routinely measured in clinical practice to examine immune balance. Typical ranges are suggested (Ig A; 1.4-0.4 mg/mL, Ig G; 8-16 mg/mL, and Ig M; 0.5-2.0 ng/mL). Low levels of Ig were observed in humoral immunodeficiency, while high levels of Ig were observed in chronic inflammatory diseases. Until now, many studies showed that Kimchi inhibited Ig E levels in the NC/nga mice atopic animal model [24,25]. Also, lactobacillus plantarum isolated from Kimchi increased the production of Ig A in normal or S180-bearing BALB/C tumor-induced mouse 56. On the other hand, 4 weeks of Kimchi supplementation does not changes of Ig A, Ig G or Ig M 55.

Gut microbiota dysbiosis plays a key role in the pathogenesis of inflammatory bowel disease (IBD). Much research has focused on the use of gut microbiota for the treatment of inflammatory bowel disease (IBD). Probiotics, live microorganisms that benefit host health, are commonly used to control chronic gastrointestinal inflammation in inflammatory bowel disease (IBD) patients. Lactobacillus and Bifidobacterium species are widely used as probiotics 57. Administration of Lactobacillus plantarum ameliorates the severity of colitis in IL-10-knockout mice 58. Lactobacillus paracasei isolated from kimchi, reduces colitis disease by decreasing the number of Th1 (IFN-γ or Interferon gamma) cells and macrophages in the lamina propria 59. Treatment with Lactobacillus acidophilus reduces the STAT3 and phosphorylated STAT3 levels in colon tissue from mice with Dextran sulfate sodium (DSS)-induced colitis and increases the number of Treg cells among intestinal intraepithelial and lamina propria lymphocytes in a 2,4,6-trinitrobenzene sulfonic acid-induced colitis model 60. Treatment with Bifidobacterium longum ameliorates colorectal colitis in rats by altering the methylation level of the Foxp3 promoter, resulting in an increased number of Treg cells 61. Moreover, Streptococcus thermophilus suppresses bacterial translocation, which reduces gastrointestinal bleeding and weight loss 62. Treatment with lactobacilli and bifidobacteria promoted recovery of Dextran sulfate sodium (DSS)-induced intestinal injury and inflammation in a mouse model of colitis 63. Lactobacillus casei and Bifidobacterium lactis ameliorated injury to the intestinal mucosa and liver in a 2,4,6-trinitrobenzene sulfonic acid-induced colitis model 64. Also, treatment with a probiotic combination that included lactobacilli, bifidobacteria, and streptococci reduced the levels of proinflammatory cytokines in colitis 65.

Cytokines, protein mediators produced by immune cells, are involved in immune regulation. The levels of pro-inflammatory cytokines are increased in chronic inflammatory diseases while the levels of anti-inflammatory cytokines are decreased. Kim et al. 18 showed that the consumption of fermented Kimchi (300 g/day for 4 weeks) had no effects on the levels of Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) in overweight and obese patients (22 subjects, mean age of 38.6 ± 8.5 years). In another study 55, the levels of TNF-α and IL-6 were significantly decreased in the Kimchi and non-Kimchi groups. It is unclear why the levels of pro-inflammatory cytokines in the non-Kimchi group were decreased. The study author 55 postulated the decreased levels of TNF-α and IL-6 in placebo group may be due to the use of radish. Because of these conflicting results more research are needed before any opinion can be formed regarding the effects of kimchi on the immune system (e.g., immune stimulating activity).

  1. Chang JY, Chang HC. Growth inhibition of foodborne pathogens by Kimchi prepared with bacteriocin-producing starter culture. J Food Sci. 2011;76:M72–M78 https://www.ncbi.nlm.nih.gov/pubmed/21535696[]
  2. Hwang HS, Han BR, Han BJ, Chung L. Korean Traditional Local Food Written by Three Generation. Paju: Kyomun Publishing Co.; 2010. pp. 1–300.[]
  3. Cheigh HS, Park KY. Biochemical, microbiological, and nutritional aspects of Kimchi (Korean fermented vegetable products) Crit Rev Food Sci Nutr. 1994;34:175–203 https://www.ncbi.nlm.nih.gov/pubmed/8011144[]
  4. Lee GI, Lee HM, Lee CH. Food safety issues in industrialization of traditional Korean foods. Food Control. 2012;24:1–5.[]
  5. Lee H, Kim DY, Lee MA, Jang J-Y, Choue R. Immunomodulatory Effects of Kimchi in Chinese Healthy College Students: A Randomized Controlled Trial. Clinical Nutrition Research. 2014;3(2):98-105. doi:10.7762/cnr.2014.3.2.98. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135247/[]
  6. Pan-genomic and transcriptomic analyses of Leuconostoc mesenteroides provide insights into its genomic and metabolic features and roles in kimchi fermentation. Scientific Reports 2017, volume 7, Article number: 11504. https://www.nature.com/articles/s41598-017-12016-z[][][][][][][]
  7. Jung, J. Y., Lee, S. H. & Jeon, C. O. Kimchi microflora: history, current status, and perspectives for industrial kimchi production. Appl Microbiol Biotechnol 2014; 98, 2385–2393[][]
  8. Jeon, H. H. et al. A proposal of Leuconostoc mesenteroides subsp. jonggajibkimchii subsp. nov. and reclassification of Leuconostoc mesenteroides subsp. suionicum (Gu et al., 2012) as Leuconostoc suionicum sp. nov. based on complete genome sequences. Int J Syst Evol Microbiol in press doi: https://doi.org/10.1099/ijsem.0.001930[][]
  9. Beganović, J. et al. Improved sauerkraut production with probiotic strain Lactobacillus plantarum L4 and Leuconostoc mesenteroides LMG 7954. J Food Sci 2011; 76, M124–M129[]
  10. Yi, Y.-J. et al. Potential use of lactic acid bacteria Leuconostoc mesenteroides as a probiotic for the removal of Pb (II) toxicity. J Microbiol 2017; 55, 296–303[]
  11. Barletta, J. et al. Meningitis due to Leuconostoc mesenteroides associated with central nervous system tuberculosis: a case report. Ann Clin Case Rep 2017; 2, 1228[]
  12. de Paula, A. T., Jeronymo-Ceneviva, A. B., Todorov, S. D. & Penna, A. L. B. The two faces of Leuconostoc mesenteroides in food systems. Food Rev Int 2015; 31, 147–171[]
  13. Choi IH, Noh JS, Han JS, Kim HJ, Han ES, Song YO. Kimchi, a fermented vegetable, improves serum lipid profiles in healthy young adults: randomized clinical trial. J Med Food. 2013;16:223–229. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598433/[]
  14. Park KY, Kil JH, Jung KO, Kong CS, Lee LM. Functional properties of Kimchi (Korean fermented vegetables) Acta Hortic. 2006;706:167–172.[]
  15. Lee YM, Kwon MJ, Kim JK, Suh HS, Choi JS, Song YO. Isolation and identification of active principle in Chinese cabbage Kimchi responsible for antioxidant effect. Korean J Food Sci Technol. 2004;36:129–133.[]
  16. Cho EJ, Rhee SH, Lee SM, Park KY. In vitro antimutagenic and anticancer effects of Kimchi fractions. J Korean Assoc Cancer Prev. 1997;2:113–121.[]
  17. Kwon MJ, Chun JH, Song YS, Song YO. Daily Kimchi consumption and its hypolipidemic effect in middle-aged men. J Korean Soc Food Sci Nutr. 1999;28:1144–1150.[]
  18. Kim EK, An SY, Lee MS, Kim TH, Lee HK, Hwang WS, Choe SJ, Kim TY, Han SJ, Kim HJ, Kim DJ, Lee KW. Fermented kimchi reduces body weight and improves metabolic parameters in overweight and obese patients. Nutr Res. 2011;31:436–443. https://www.ncbi.nlm.nih.gov/pubmed/21745625[][]
  19. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[]
  20. Choi IH, Noh JS, Han J-S, Kim HJ, Han E-S, Song YO. Kimchi, a Fermented Vegetable, Improves Serum Lipid Profiles in Healthy Young Adults: Randomized Clinical Trial. Journal of Medicinal Food. 2013;16(3):223-229. doi:10.1089/jmf.2012.2563. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598433/[][]
  21. Lee YM, Kwon MJ, Kim JK, Suh HS, Choi JS, Song YO: Isolation and identification of active principle in Chinese cabbage kimchi responsible for antioxidant effect. Korean J Food Sci Technol 2004;36:129–133[]
  22. Kim JH, Ryu JD, Lee HG, et al. The effect of kimchi on production of free radicals and anti-oxidative enzyme activities in the brain of SAM. J Korean Soc Food Sci Nutr. 2002;31:117–123.[]
  23. Park JA, Tirupathi Pichiah PB, Yu JJ, Oh SH, Daily JW, 3rd, Cha YS. Anti-obesity effect of kimchi fermented with Weissella koreensis OK1-6 as starter in high-fat diet-induced obese C57BL/6J mice. J Appl Microbiol. 2012;113:1507–1516 https://www.ncbi.nlm.nih.gov/pubmed/22978326[]
  24. Kim H, Oh SY, Kang MH, Kim KN, Kim Y, Chang N. Association between kimchi intake and asthma in Korean adults: the fourth and fifth Korea National Health and Nutrition Examination Survey (2007-2011) J Med Food. 2014;17:172–178 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901325/[]
  25. Kim JH, Ryu JD, Lee HG, Park JH: The effect of kimchi on production of free radicals and anti-oxidative enzyme activities in the brain of SAM. J Korean Soc Food Sci Nutr 2002;31:117–123[]
  26. Park KY: The nutritional evaluation and anti-mutagenic and anticancer effects of kimchi. J Korean Soc Food Sci Nutr 1995;24:169–182[]
  27. Wang Y, Li F, Wang Z, Qiu T, Shen Y, Wang M. Fruit and vegetable consumption and risk of lung cancer: a dose-response meta-analysis of prospective cohort studies. Lung Cancer. 2015;88:124–130. https://www.ncbi.nlm.nih.gov/pubmed/25747805[]
  28. Park KY, Jeong JK, Lee YE, Daily JW., 3rd Health benefits of kimchi (Korean fermented vegetables) as a probiotic food. J Med Food. 2014;17:6–20. https://www.ncbi.nlm.nih.gov/pubmed/24456350[]
  29. Choi EA, Chang HC. Cholesterol-lowering effects of a putative probiotic strain Lactobacillus plantarum EM isolated from kimchi. LWT – Food Sci Technol (Campinas) 2015;62:210–217.[]
  30. Sheo HJ, Seo YS: The antibacterial action of Chinese cabbage kimchi juice on Staphylococcus aureus, Salmonella enteritidis, Vibrio parahaemolyticus and Enterobacter cloacae. J Korean Soc Food Sci Nutr 2003;32:1351–1356[]
  31. Kim MJ, Kwon MJ, Song YO, Lee EK, Youn HJ, Song YS: The effects of kimchi on hematological and immunological parameters in vivo and in vitro. J Korean Soc Food Sci Nutr 1997;26:1–7[]
  32. Kwon JY, Cheigh HS, Song YO: Weight reduction and lipid lowering effects of kimchi lactic acid powder in rats fed high fat diets. Korean J Food Sci Technol 2004;36:1014–1019[]
  33. Noh JS, Kim HJ, Kwon MJ, Song YO: Active principle of kimchi, 3-(40-hydroxyl-3050-dimethoxyphenyl)propionic acid, retards fatty streak formation at aortic sinus of apolipoprotein E knockout mice. J Med Food 2009;12:1206–1212 https://www.ncbi.nlm.nih.gov/pubmed/20041773[]
  34. Sheela CG. Augusti KT. Effects of S-allyl cysteine sulfoxide isolated from Allium sativm Linn and gugulipid on some enzymes and fecal excretions of bile and acids and sterols in cholesterol fed rats. Indian J Exp Biol. 1995;33:749–751 https://www.ncbi.nlm.nih.gov/pubmed/8575806[][]
  35. Miettinen TA. Vanhanen H. Dietary sitosterol related to absorption, synthesis and serum level of cholesterol in different apolipoprotein E phenotypes. Atherosclerosis. 1994;105:217–226 https://www.ncbi.nlm.nih.gov/pubmed/8003098[]
  36. Kawada T. Hagihara K. Iwai K. Effects of capsaicin on lipid metabolism in rats fed a high fat diet. J Nutr. 1986;116:1272–1278. https://www.ncbi.nlm.nih.gov/pubmed/2875141[]
  37. Yoshioka M. St-Pierre S. Suzuki M. Tremblay A. Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. Br J Nutr. 1998;80:503–510. https://www.ncbi.nlm.nih.gov/pubmed/10211048[]
  38. Gilliland SE. Health and nutritional benefits from lactic acid bacteria. FEMS Microbiol Rev. 1990;7:175–188. https://www.ncbi.nlm.nih.gov/pubmed/2271223[]
  39. Kwon MJ. Song YO. Song YS. Effects of kimchi on tissue and fecal lipid composition and apolipoprotein and thyroxine levels in rats. J Korean Soc Food Sci Nutr. 1997;26:507–513.[]
  40. Kim HJ. Kwon MJ. Seo JM, et al. The effect of 3-(4′-hydroxyl-3′5′-dimethoxyphenyl)propionic acid in Chinese cabbage kimchi on lowering hypercholesterolemia. J Korean Soc Food Sci Nutr. 2004;33:52–58.[]
  41. Choi IH, Noh JS, Han J-S, Kim HJ, Han E-S, Song YO. Kimchi, a Fermented Vegetable, Improves Serum Lipid Profiles in Healthy Young Adults: Randomized Clinical Trial. Journal of Medicinal Food. 2013;16(3):223-229. doi:10.1089/jmf.2012.2563.[][][]
  42. Fermented kimchi reduces body weight and improves metabolic parameters in overweight and obese patients. Nutrition Research Volume 31, Issue 6, June 2011, Pages 436-443. https://www.sciencedirect.com/science/article/pii/S027153171100114X[][]
  43. Chu YF, Sun J, Wu X, Liu RH. Antioxidant and antiproliferative activities of common vegetables. J Agric Food Chem. 2002;50:6910–6916 https://www.ncbi.nlm.nih.gov/pubmed/12405796[]
  44. Moriarty RM, Naithani R, Surve B. Organosulfur compounds in cancer chemoprevention. Mini Rev Med Chem. 2007;7:827–838. https://www.ncbi.nlm.nih.gov/pubmed/17692044[]
  45. Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr. 2001;131:955S–962S. https://www.ncbi.nlm.nih.gov/pubmed/11238796[]
  46. Salman H, Bergman M, Bessler H, Punsky I, Djaldetti M. Effect of a garlic derivative (alliin) on peripheral blood cell immune responses. Int J Immunopharmacol. 1999;21:589–597. https://www.ncbi.nlm.nih.gov/pubmed/10501628[]
  47. Singh S, Natarajan K, Aggarwal BB. Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is a potent inhibitor of nuclear transcription factor-kappa B activation by diverse agents. J Immunol. 1996;157:4412–4420. https://www.ncbi.nlm.nih.gov/pubmed/8906816[]
  48. Lee YM. Kwon MJ. Kim JK. Suh HS. Choi JS. Song YO. Isolation and identification of active principle in Chinese cabbage kimchi responsible for antioxidant effect. Korean J Food Sci Technol. 2004;36:129–133.[]
  49. 3-(4′-hydroxyl-3′,5′-dimethoxyphenyl)propionic acid, an active principle of kimchi, inhibits development of atherosclerosis in rabbits. Kim HJ, Lee JS, Chung HY, Song SH, Suh H, Noh JS, Song YO. J Agric Food Chem. 2007 Dec 12; 55(25):10486-92. https://www.ncbi.nlm.nih.gov/pubmed/18004805/[]
  50. Active principle of kimchi, 3-(4′-hydroxyl-3′,5′-dimethoxyphenyl)propionic acid, retards fatty streak formation at aortic sinus of apolipoprotein E knockout mice. Noh JS, Kim HJ, Kwon MJ, Song YO. J Med Food. 2009 Dec; 12(6):1206-12. https://www.ncbi.nlm.nih.gov/pubmed/20041773/[]
  51. Fermented kimchi reduces body weight and improves metabolic parameters in overweight and obese patients. Kim EK, An SY, Lee MS, Kim TH, Lee HK, Hwang WS, Choe SJ, Kim TY, Han SJ, Kim HJ, Kim DJ, Lee KW. Nutr Res. 2011 Jun; 31(6):436-43. https://www.ncbi.nlm.nih.gov/pubmed/21745625/[]
  52. Lee H, Lee IS, Choue R. Obesity, inflammation and diet. Pediatr Gastroenterol Hepatol Nutr. 2013;16:143–152. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819692/[]
  53. Krehbiel CR, Rust SR, Zhang G, Gilliland SE. Bacterial direct-fed microbials in ruminant diets: performance response and mode of action. J Anim Sci. 2003;81:E120–E132.[]
  54. Lee JW, Shin JG, Kim EH, Kang HE, Yim IB, Kim JY, Joo HG, Woo HJ. Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum. J Vet Sci. 2004;5:41–48. https://www.ncbi.nlm.nih.gov/pubmed/15028884[]
  55. Lee H, Kim DY, Lee MA, Jang J-Y, Choue R. Immunomodulatory Effects of Kimchi in Chinese Healthy College Students: A Randomized Controlled Trial. Clinical Nutrition Research. 2014;3(2):98-105. doi:10.7762/cnr.2014.3.2.98 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135247/[][][][]
  56. Won TJ, Kim B, Lim YT, Song DS, Park SY, Park ES, Lee DI, Hwang KW. Oral administration of Lactobacillus strains from Kimchi inhibits atopic dermatitis in NC/Nga mice. J Appl Microbiol. 2011;110:1195–1202 https://www.ncbi.nlm.nih.gov/pubmed/21338447[]
  57. Stanton C, Gardiner G, Meehan H, Collins K, Fitzgerald G, Lynch PB, Ross RP. Market potential for probiotics. Am J Clin Nutr. 2001;73:476S–483S. doi: 10.1093/ajcn/73.2.476s https://www.ncbi.nlm.nih.gov/pubmed/11157361[]
  58. Xia Y, Chen HQ, Zhang M, Jiang YQ, Hang XM, Qin HL. Effect of Lactobacillus plantarum LP-Onlly on gut flora and colitis in interleukin-10 knockout mice. J Gastroenterol Hepatol. 2011;26:405–411. doi: 10.1111/j.1440-1746.2010.06498.x https://www.ncbi.nlm.nih.gov/pubmed/21261733[]
  59. Park JS, Joe I, Rhee PD, Jeong CS, Jeong G. A lactic acid bacterium isolated from kimchi ameliorates intestinal inflammation in DSS-induced colitis. J Microbiol. 2017;55:304–310. doi: 10.1007/s12275-017-6447-y https://www.ncbi.nlm.nih.gov/pubmed/28124779[]
  60. Roselli M, Finamore A, Nuccitelli S, Carnevali P, Brigidi P, Vitali B, Nobili F, Rami R, Garaguso I, Mengheri E. Prevention of TNBS-induced colitis by different Lactobacillus and Bifidobacterium strains is associated with an expansion of gammadeltaT and regulatory T cells of intestinal intraepithelial lymphocytes. Inflamm Bowel Dis. 2009;15:1526–1536. doi: 10.1002/ibd.20961 https://www.ncbi.nlm.nih.gov/pubmed/19504616[]
  61. Zhang M, Zhou L, Zhang S, Yang Y, Xu L, Hua Z, Zou X. Bifidobacterium longum affects the methylation level of forkhead box P3 promoter in 2, 4, 6-trinitrobenzenesulphonic acid induced colitis in rats. Microb Pathog. 2017;110:426–430. doi: 10.1016/j.micpath.2017.07.029 https://www.ncbi.nlm.nih.gov/pubmed/28733028[]
  62. Bailey JR, Vince V, Williams NA, Cogan TA. Streptococcus thermophilus NCIMB 41856 ameliorates signs of colitis in an animal model of inflammatory bowel disease. Benef Microbes. 2017;8:605–614. doi: 10.3920/BM2016.0110 https://www.ncbi.nlm.nih.gov/pubmed/28618865[]
  63. Toumi R, Soufli I, Rafa H, Belkhelfa M, Biad A, Touil-Boukoffa C. Probiotic bacteria lactobacillus and bifidobacterium attenuate inflammation in dextran sulfate sodium-induced experimental colitis in mice. Int J Immunopathol Pharmacol. 2014;27:615–627. doi: 10.1177/039463201402700418 https://www.ncbi.nlm.nih.gov/pubmed/25572742[]
  64. Bellavia M, Rappa F, Lo Bello M, Brecchia G, Tomasello G, Leone A, Spatola G, Uzzo ML, Bonaventura G, David S, et al. Lactobacillus casei and bifidobacterium lactis supplementation reduces tissue damage of intestinal mucosa and liver after 2,4,6-trinitrobenzenesulfonic acid treatment in mice. J Biol Regul Homeost Agents. 2014;28:251–261 https://www.ncbi.nlm.nih.gov/pubmed/25001657[]
  65. Kim MS, Byun JS, Yoon YS, Yum DY, Chung MJ, Lee JC. A probiotic combination attenuates experimental colitis through inhibition of innate cytokine production. Benef Microbes. 2017;8:231–241. doi: 10.3920/BM2016.0031 https://www.ncbi.nlm.nih.gov/pubmed/28008786[]
read more

Cucumber

cucumber

What is a cucumber

Cucumber (Cucumis sativus L.) is a widely cultivated fruit and it’s a member of the Cucurbitaceae family, which includes species with therapeutic potential such as melon, squash, and pumpkin 1. Cucumber is a creeping vine that bears cucumiform fruits but are eaten as vegetables. Cucumber is widely consumed fresh in salads or fermented (pickles) or as a cooked vegetable. The cucumber is originally from South Asia, but now grows on most continents. Many different types of cucumber are traded on the global market. Cucumber is susceptible to fruit rot caused by the oomycete pathogen, Phytophthora capsici 2. Though Phytophthora capsici infects vegetative tissues in most crops, in cucumber, the fruits are the primary target of infection 3. Cucumber is primarily eaten immature, and they’re typically harvested at 8–12 days post-pollination, while fruit ripening and seed maturity is at ~30–35 days post-pollination 4.

Cucumber varieties

Cucumbers are classified into three main cultivar groups: “slicing”, “pickling”, and “burpless”.

Slicing cucumber

Cucumbers grown to eat fresh are called slicing cucumbers. The main varieties of slicers mature on vines with large leaves that provide shading. They are mainly eaten in the unripe green form, since the ripe yellow form normally becomes bitter and sour. Slicers grown commercially for the North American market are generally longer, smoother, more uniform in color, and have a much tougher skin. Slicers in other countries are smaller and have a thinner, more delicate skin, often having fewer seeds and being sold in a plastic skin for protection. Sometimes these are known as English cucumbers. This variety may also be called a “telegraph cucumber”, particularly in Australasia. Smaller slicing cucumbers can also be pickled.

Pickling cucumber

Pickling with brine, sugar, vinegar, and spices creates various, flavored products from cucumbers and other foods. Although any cucumber can be pickled, commercial pickles are made from cucumbers specially bred for uniformity of length-to-diameter ratio and lack of voids in the flesh. Those cucumbers intended for pickling, called picklers, grow to about 7 to 10 cm (3 to 4 in) long and 2.5 cm (1 in) wide. Compared to slicers, picklers tend to be shorter, thicker, less regularly shaped, and have bumpy skin with tiny white or black-dotted spines. Color can vary from creamy yellow to pale or dark green. The process of pickling led to the use of paraffin wax as a seal for jars used to preserve pickled and other preserved foods, and to the Mason jar made from thick glass able to tolerate high temperatures used in processing pickles and other foods for long-term shelf-life. The liquid made from pickling is called “pickle juice.”

Gherkin

Gherkins, also called cornichons, baby dills, or baby pickles, are small, whole, unsliced cucumbers, typically those 1 inch (2.5 cm) to 5 inches (13 cm) in length, often with bumpy skin, and pickled in variable combinations of brine, vinegar, spices, and sugar. In the United Kingdom, gherkins may be prepared predominantly in vinegar, imparting an acidic flavor “punch” as a side-dish for meals.

Although gherkins may be grown in greenhouses, they are commonly grown as a field crop, processed locally, and packaged in jars in Canada, the United States, and India. India, Turkey, Ukraine and Mexico compete as producers for the global gherkin market, with the European Union, United States, Canada, and Israel as major importers.

The word gherkin derived in the mid-17th century from early modern Dutch, gurken or augurken for “small pickled cucumber”. The term, West Indian gherkin, has been applied to Cucumis anguria L., a related species of Cucumis sativus, the most common cucumber plant.

Burpless cucumber

Burpless cucumbers are sweeter and have a thinner skin than other varieties of cucumber, and are reputed to be easy to digest and to have a pleasant taste. They can grow as long as 2 feet (0.61 m). They are nearly seedless, and have a delicate skin. Most commonly grown in greenhouses, these parthenocarpic cucumbers are often found in grocery markets, shrink-wrapped in plastic. They are sometimes marketed as seedless or burpless, because the seeds and skin of other varieties of cucumbers are said to give some people gas.

Other cultivars

  • Lebanese cucumbers are small, smooth-skinned and mild, yet with a distinct flavor and aroma. Like the English cucumber, Lebanese cucumbers are nearly seedless.
  • East Asian cucumbers are mild, slender, deep green, and have a bumpy, ridged skin. They can be used for slicing, salads, pickling, etc., and are available year-round. They are usually burpless as well.
  • Persian cucumber, which are mini, seedless, and slightly sweet, are available from Canada during the summer, and all year-round in the US. Easy to cut and peel, it is on average 4–7 in (10–18 cm) long. They are commonly eaten chopped up in plain yogurt with mint or sliced thin and long with salt and lemon juice. Vines are parthenocarpic, requiring no pollinators for fruit set.
  • Beit Alpha cucumbers are small, sweet parthenocarpic cucumbers adapted to the dry climate of the Middle East.
  • Apple cucumbers are short, round cucumbers grown in New Zealand and parts of Europe, known for their light yellow-green color and mildly sweet flavor. When mature, the fruit may grow tiny spines, and contains numerous edible green seeds. The fruit is usually eaten raw, with skin.
  • Schälgurken cucumbers are eaten in Germany. Their thick skins are peeled and then they braised or fried, often with minced meat or dill. They are often known by the term ‘Schmorgurken’.
  • Dosakai is a yellow cucumber available in parts of India. These fruits are generally spherical in shape. It is commonly cooked as curry, added in sambar or soup, daal and also in making dosa-aavakaaya (Indian pickle) and chutney; it is also grown and available through farms in Central California.
  • Kekiri is a smooth skinned cucumber, relatively hard, and not used for salads. It is cooked as spicy curry. It is found in dry zone of Sri Lanka. It becomes orange colored when the fruit is matured.
  • Armenian cucumbers (also known as yard long cucumbers) are fruits produced by the plant Cucumis melo var. flexuosus. This is not the same species as the common cucumber (Cucumis sativus) although it is closely related. Armenian cucumbers have very long, ribbed fruit with a thin skin that does not require peeling, but are actually an immature melon. This is the variety sold in Middle Eastern markets as “pickled wild cucumber”.

Cucumber nutrition

In a 100-gram serving, raw cucumber (with peel) is 95% water, provides 67 kilojoules (16 Calories) and supplies low content of essential nutrients, as it is notable only for vitamin K at 16% of the Daily Value.

Table 1. Cucumber (raw) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg95.23
Energykcal15
EnergykJ65
Proteing0.65
Total lipid (fat)g0.11
Ashg0.38
Carbohydrate, by differenceg3.63
Fiber, total dietaryg0.5
Sugars, totalg1.67
Sucroseg0.03
Glucose (dextrose)g0.76
Fructoseg0.87
Lactoseg0
Maltoseg0.01
Galactoseg0
Starchg0.83
Minerals
Calcium, Camg16
Iron, Femg0.28
Magnesium, Mgmg13
Phosphorus, Pmg24
Potassium, Kmg147
Sodium, Namg2
Zinc, Znmg0.2
Copper, Cumg0.041
Manganese, Mnmg0.079
Selenium, Seµg0.3
Fluoride, Fµg1.3
Vitamins
Vitamin C, total ascorbic acidmg2.8
Thiaminmg0.027
Riboflavinmg0.033
Niacinmg0.098
Pantothenic acidmg0.259
Vitamin B-6mg0.04
Folate, totalµg7
Folic acidµg0
Folate, foodµg7
Folate, DFEµg7
Choline, totalmg6
Betainemg0.1
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg5
Retinolµg0
Carotene, betaµg45
Carotene, alphaµg11
Cryptoxanthin, betaµg26
Vitamin A, IUIU105
Lycopeneµg0
Lutein + zeaxanthinµg23
Vitamin E (alpha-tocopherol)mg0.03
Vitamin E, addedmg0
Tocopherol, betamg0.01
Tocopherol, gammamg0.03
Tocopherol, deltamg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg16.4
Lipids
Fatty acids, total saturatedg0.037
04:00:00g0
06:00:00g0
8:0g0
10:0g0
12:0g0
14:0g0.005
15:0g0
16:0g0.028
17:0g0
18:0g0.005
20:0g0
22:0g0
24:0g0
Fatty acids, total monounsaturatedg0.005
14:1g0
15:1g0
16:1 undifferentiatedg0
17:1g0
18:1 undifferentiatedg0.005
20:1g0
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg0.032
18:2 undifferentiatedg0.028
18:3 undifferentiatedg0.005
18:4g0
20:2 n-6 c,cg0
20:3 undifferentiatedg0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Fatty acids, total transg0
Cholesterolmg0
Phytosterolsmg14
Amino Acids
Tryptophang0.005
Threonineg0.019
Isoleucineg0.021
Leucineg0.029
Lysineg0.029
Methionineg0.006
Cystineg0.004
Phenylalanineg0.019
Tyrosineg0.011
Valineg0.022
Arginineg0.044
Histidineg0.01
Alanineg0.024
Aspartic acidg0.041
Glutamic acidg0.196
Glycineg0.024
Prolineg0.015
Serineg0.02
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
Flavan-3-ols
(+)-Catechinmg0
(-)-Epigallocatechinmg0
(-)-Epicatechinmg0
(-)-Epicatechin 3-gallatemg0
(-)-Epigallocatechin 3-gallatemg0
(+)-Gallocatechinmg0
Flavones
Apigeninmg0
Luteolinmg0
Flavonols
Isorhamnetinmg0
Kaempferolmg0.1
Myricetinmg0
Quercetinmg0
Isoflavones
Daidzeinmg0
Genisteinmg0
Total isoflavonesmg0
Proanthocyanidin
Proanthocyanidin dimersmg0
Proanthocyanidin trimersmg0
Proanthocyanidin 4-6mersmg0
Proanthocyanidin 7-10mersmg0
Proanthocyanidin polymers (>10mers)mg0
[Source: United States Department of Agriculture Agricultural Research Service 5]

Table 2. Cucumber (raw and peeled) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg96.73
Energykcal10
EnergykJ44
Proteing0.59
Total lipid (fat)g0.16
Ashg0.36
Carbohydrate, by differenceg2.16
Fiber, total dietaryg0.7
Sugars, totalg1.38
Sucroseg0
Glucose (dextrose)g0.63
Fructoseg0.75
Lactoseg0
Maltoseg0
Galactoseg0
Starchg0.08
Minerals
Calcium, Camg14
Iron, Femg0.22
Magnesium, Mgmg12
Phosphorus, Pmg21
Potassium, Kmg136
Sodium, Namg2
Zinc, Znmg0.17
Copper, Cumg0.071
Manganese, Mnmg0.073
Selenium, Seµg0.1
Fluoride, Fµg1.3
Vitamins
Vitamin C, total ascorbic acidmg3.2
Thiaminmg0.031
Riboflavinmg0.025
Niacinmg0.037
Pantothenic acidmg0.24
Vitamin B-6mg0.051
Folate, totalµg14
Folic acidµg0
Folate, foodµg14
Folate, DFEµg14
Choline, totalmg5.7
Betainemg0.1
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg4
Retinolµg0
Carotene, betaµg31
Carotene, alphaµg8
Cryptoxanthin, betaµg18
Vitamin A, IUIU72
Lycopeneµg0
Lutein + zeaxanthinµg16
Vitamin E (alpha-tocopherol)mg0.03
Vitamin E, addedmg0
Tocopherol, betamg0
Tocopherol, gammamg0.02
Tocopherol, deltamg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg7.2
Lipids
Fatty acids, total saturatedg0.078
04:00:00g0
06:00:00g0
8:0g0
10:0g0
12:0g0
14:0g0.01
15:0g0
16:0g0.058
17:0g0
18:0g0.01
20:0g0
22:0g0
24:0g0
Fatty acids, total monounsaturatedg0.01
14:1g0
15:1g0
16:1 undifferentiatedg0
17:1g0
18:1 undifferentiatedg0.01
20:1g0
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg0.019
18:2 undifferentiatedg0.01
18:3 undifferentiatedg0.01
18:4g0
20:2 n-6 c,cg0
20:3 undifferentiatedg0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Fatty acids, total transg0
Cholesterolmg0
Amino Acids
Tryptophang0.007
Threonineg0.012
Isoleucineg0.012
Leucineg0.025
Lysineg0.025
Methionineg0.012
Cystineg0.007
Phenylalanineg0.031
Tyrosineg0.002
Valineg0.012
Arginineg0.031
Histidineg0.002
Alanineg0.031
Aspartic acidg0.037
Glutamic acidg0.204
Glycineg0.025
Prolineg0.012
Serineg0.025
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
Isoflavones
Daidzeinmg0
Genisteinmg0
Total isoflavonesmg0
Proanthocyanidin
Proanthocyanidin dimersmg0
Proanthocyanidin trimersmg0
Proanthocyanidin 4-6mersmg0
Proanthocyanidin 7-10mersmg0
Proanthocyanidin polymers (>10mers)mg0
[Source: United States Department of Agriculture Agricultural Research Service 5]

Health benefits of cucumber

Cucumber is a popular crop used in Indian traditional medicine since ancient times. Traditionally, cucumber plant has been used to treat headaches and hyperlipidemia, and to prevent constipation 1. Cucumber seeds and cucumber fruit have refreshing properties, soothing irritated skin and reducing swelling 6. Cucumber is very high in water content and very low in calories. Cucumber has potential anti-diabetic, anti-hyperglycemic, lipid lowering and antioxidant activity in animal studies 7, 8. Cucumber has a cleansing action within the body by removing accumulated pockets of old waste materials and chemical toxins 7. Fresh cucumber fruit juice is used for nourishing the skin 7. It gives a soothing effect against skin irritations and reduces swelling. Cucumber also has the power to relax and alleviate the sunburn’s pain 7. The cucumber fruit is refrigerant (cooling), hemostatic (an agent that causes bleeding to stop), tonic and useful in hyperdipsia (intense thirst), sunstroke (heat stroke) 7. The cucumber seeds also have a cooling effect on the body and they are used to prevent constipation 7. Several bioactive compounds have been isolated from cucumber including cucurbitacins, cucumegastigmanes I and II, cucumerin A and B, vitexin, orientin, isoscoparin 2″-O-(6‴-(E)-p-coumaroyl) glucoside, apigenin 7-O-(6″-O-p-coumaroylglucoside) 7. Despite huge exploration of cucumber in agricultural field, comparatively very few studies have been published about its chemical profile and its therapeutic potential.

Moreover, cucumber has been reported to have antiinflammatory and antioxidant properties 9.

Cucumber is known to be rich in cucurbitacins 10. Cucurbitacins are mostly found in the members of the family Cucurbitaceae and are responsible for the bitter taste of cucumber. Pharmacological activities such as anti-bacterial and anti-tumor effects have been attributed to these structurally diverse triterpens 10. Cucurbitacins have become interesting subjects in science due to their medicinal and toxic properties 11. Cucurbitacins are usually concentrated in fruits and roots at maturity and are responsible for bitter taste of cucumber. Cucumber seeds exhibit very low concentration of cucurbitacins 12. The diversity of cucurbitacins lies in side chain derivatives that contribute to pharmacological actions 13. They are known according to their structural composition and designated by the letters: A, B, C, D, E, F, G, H, I, J, K, L, O, P, Q, R and S. Cucurbitacins have also been identified outside the cucurbitaceae family including members of Scrophulariaceae, Begoniaceae, Primulaceae, Liliaceae, Tropaeolaceae and Rosaceae families 14. Various cucurbitacins are made from chemical modification of cucurbitane (19(10–9ß)-abeo-5α-lanostane) with numerous activities such as anti-inflammatory, antitumor promotion, chemopreventive, hepatoprotective, anti-microbial, anthelmintic, antifeedant and antioxidant 15. CuE is one of the cucurbitacins and is an active secondary methabolite with inhibition of cell adhesion actions 16 and modulatory activity effect on the peripheral human lymphocytes 17. The compound has also been found to be a strong antifeedant for the flea beetle, bilirubin–albumin binding in human plasma and with inhibitory activity on cancer cell proliferation, actin polymerization and permeability 16. The compound also acts as agent to protect against certain diseases in plants due to its toxicity property 18. Cu E displays superior cytotoxicity due to more hydrophobicity than the other cucurbitacins 19.

Various biological activities attributed to Cucurbitacins with probable mechanish of action (s) have been summarized in Table 3 below.

Figure 1. Cucurbitacin analogs chemical structures

Cucurbitacin analogs chemical structures

[Source 12]

Table 3. Reported biological activities of cucurbitacins with probable mechanism of action

cucurbitacins biological activities

[Source 12]

Anti-inflammatory activity

Cucurcitacin analogues viz. Cucurbitacin R and DHCB have been reported to possess anti-inflammatory potential and their action is reported to be mediated by inhibition of tumor necrosis factors (TNF)-α and other mediators of inflammation such as nitric-oxide synthase-2 and cyclo-oxygenase-2 20. Cucurbitacins B, D, E and I have been reported to inhibit cyclooxygenase (COX)-2 enzymes with no effect on COX-1 enzymes 21. The anti-inflammatory response of 23, 24-dihydrocucurbitacin D (DHCD) have been hypothesized to get mediated through blocking of NF-κ B activation thereby obstructing the release of nitrous oxide. DHCD can be taken up as probable lead and appraised for providing a promising anti-inflammatory agent 22.

Antitumor activity

Very less information is available on the role of Cucurbitacins at molecular level which has lead to slow advancement in the development of Cucurbitacins as anti-cancer agents. Cucurbitacin B (CuB) is a naturally occurring compound that is found abundantly in cucumbers and other vegetables, and it is known to exert anti-cancer activities (primarily via apoptosis-induction) in several human cancers 23. Cucurbitacin B, a bioactive compound from cucumber, inhibits prostate cancer growth 23. In relation to cancer, targets of Cucurbitacin actions involve growth inhibition, arrest of cell cycle at G2/M phase and induction of apoptosis in cancer cell. The mechanisms underlying anti-tumorigenic potentials of Cucurbitacins involve inhibition of Janus kinase/Signal Transducer Activator of Transcription 3 (JAK/STAT3) signaling pathway whose activation is required for the proliferation and sustainment of cells. The role of Cucurbitacin I in suppressing phosphotyrosine STAT3 in cancer cell lines and cancerous lung cells of humans has been reported 24. Although Cucurbitacin B, E, and I act by inhibiting the activation of both JAK2 and STAT3, Cucurbitacin A and I acts by inhibition of only JAK2 and STAT3 respectively 25. It has been reported that Cucurbitacin E inhibited tumor angiogenesis by inhibiting JAK-STAT3 and mitogen activated protein kinases (MAPK)- signaling pathways 26. The role of interference with actin cytoskeleton has been attributed to anti-proliferative effects of Cucurbitacin B and E. The anti-proliferative activities have been correlated directly with the disruption of the F-actin cytoskeleton 27. It has been proposed that the combination of Cucurbitacin B with docetaxel may augment the chemotherapeutic effects by suppression STAT3 in patients with laryngeal cancer 28. It is expected that cucumber fruits have anti-tumor effects since they have been reported to contain Cucurbitacin C 29. It has been reported that cucurbitacin B exerts an anticancer effect by inhibiting telomerase via down-regulating both the human telomerase reverse transcriptase and c-Myc expression in breast cancer cells 30.

Anti-artherosclerotic activity

There have been reports on Cucurbitacin B and E in glycosidic form to exhibit inhibitory effect on lipid oxidation products like- malonaldehyde and 4-hydroxynonenal 31. These reports bolster the therapeutic role of Cucurbitacins in artherosclerosis, which involves modification of lipoproteins by involvement of- malonaldehyde and 4-4-hydroxynonenal 32.

Antidiabetic activity

There have been a plethora of reports on the role of Cucurbitacins for their cytotoxic, hepatoprotective, cardiovascular, and antidiabetic effects 33. Cucurbitane triterpenoids present in momordica fruits (bitter melon) are noted for antidiabetic and anticancer activities, this may provide leads as a class of therapeutics for diabetes and obesity 34. The 5’-adenosine monophosphate-activated protein kinase (AMPK) pathway is suggested as a probable mechanism for the stimulation of GLUT4 translocation by triterpenoids from M. charantia. It is particularly interesting in relation to diabetes and obesity because activation of AMPK increases fatty acid oxidation, inhibits lipid synthesis, and can improve insulin action 35. An analogue of 23,24-dihydrocucurbitacin F from Hintonia latiflora has been reported to possess significant hypoglycemic and antihyperglycemic effects. The probable mechanism underlying– antihyperglycemic effect could be stimulation of insulin release and regulation of hepatic glycogen metabolism 36.

Free Radical Scavenging and Analgesic Activities

The aqueous fruit extract of cucumber (Cucumis sativus L.) was screened for free radical scavenging and analgesic activities. The cucumber extract was subjected to in vitro antioxidant studies at 250 and 500 μg/ml and analgesic study at the doses 250 and 500 mg/kg, respectively 37. The free radical scavenging was compared with ascorbic acid, BHA (Butylated hydroxyl anisole), whereas, the analgesic effect was compared with Diclofenac sodium (50 mg/kg). The cucumber fruit extract showed maximum antioxidant and analgesic effect at 500 μg/ml and 500 mg/kg, respectively 37. The presence of flavonoids and tannins in the extract as evidenced by preliminary phytochemical screening suggests that these compounds might be responsible for free radical scavenging and analgesic effects 37.

Anti-encephalitogenic effects

Cucumber leaf extract was characterized by the predominance of triterpenoids cucurbitacins and significant levels of phenolics. Effects of cucumber leaf extract on CD4+ T helper cells and macrophages, as the major encephalitogenic  (tending to cause encephalitis) cells in the autoimmunity of the central nervous system were investigated in this study 38. Cucumber leaf extract potently inhibited production of major pathogenic CD4+ T helper cells cytokines: interferon-gamma and interleukin-17, as well as of nitric oxide and reactive oxygen species in macrophages 38. Antigen-presenting activity of macrophages and dendritic cells was also affected by cucumber leaf extract 38. The effects of cucumber leaf extract were co-incident with modulation of NFκB and p38 mitogen associated protein kinase signaling. Concentrations of cucumber leaf extract used in vitro did not show toxic effects on zebrafish embryos. Moreover, cucumber leaf extract inhibited generation of encephalitogenic cells in animal study. These results demonstrate that cucumber leaf extract deserve further investigation on its anti-encephalitogenic therapeutic properties 38.

Ulcerative colitis in laboratory animals

In acetic acid induced ulcerative colitis in wistar rats study 39 showed pretreatment with cucumber aqueous extract for 7 days exhibited significant effect in lowering of ulcer area, ulcer index as well as neutrophil infiltration at a dose of 250 and 500 mg/kg in acetic acid induced colitis 39. That animal study demonstrated cucumber aqueous extract is of potent therapeutic value in the amelioration of experimental colitis in laboratory animals by inhibiting the inflammatory mediator. However more test tube and animal studies are needed to identify the bioactive compounds.

Miscellaneous activity

It has been reported that the concentration of Cucurbitacin C in the leaves is an important parameter in spider mite resistance in cucumber, perhaps by acting as an antagonist of a spider mite ecdysteroid receptor 40. The steroid like resemblance of Cucurbitacin D may possess therapeutic effects via inhibition of Na+/K+-ATPase 41. The role of Cucurbitacins as preventive and radical scavenging antioxidant has also been reported 42. Cucurbitacins have also been reported to possess adaptogenic activity. Cucurbitacins have been reported to increase the rat capillary permeability and to demonstrate antifertility effects in female mice 43. Cucurbitacin D has been reported to inhibit ovulation in mice. There has been protective role of Cucurbitacins acting as allomones in many plant species. Role of Cucurbitacins as anti-feedants for few insects, birds and as kairomones (Cucurbitacin B, E, D, I and L) for diabroticite beetles have been reported 44. It is reported that Cucurbitacins act via Cuc receptors located on the maxillary palpi. They arrest the searching behavior of diabroticite beetles and produce a compulsive feeding behavior 45. Role of Cucurbitacin B and D in controlling diabrotic beetles can be an interesting approach 46.

Cucurbitacins Toxicity Reports

Cucurbitacins have been reported as highly toxic compounds and instances of severe poisoning and death in sheep and cattle that consumed bitter fruits of Cucumis and Cucurbita are well documented 47. The range of toxicity of Cucurbitacins based on few in-vivo toxicity reports, has been found to be between 2 -12.5 mg/kg. Although a report on toxicity of Cucurbitacin R at level as high as 375 mg/Kg p.o and 67 mg/kg i.p is available.[65] The presence of a double bond at C-23 and acetyl group at C-25 have been found to augment the toxicity of Cucurbitacins.[66] Cucurbitacin’s strong biological activity was found to be very close to their toxic dose, which renders them unlikely to be biological agents.[48] The extreme bitterness of Cucurbitacins should deter humans from being exposed to substantial quantities of the compounds. Nevertheless, some poisonings have been reported after consumption of Cucurbitaceous food plants.[8] Cucurbitacins are found to be fatal when fruits of Luffa cylindrical (L.) were consumed.[67] Gastrointestinal symptoms have also been reported in a Japanese population consuming the bottle gourd, which contained Cucurbitacin D.[68] The toxicity of Cucurbitacins C, D, E, and I have been assessed and these compounds ascertained to be lethal. Plants with Cucurbitacins C, D, E and I must be avoided as their consumption can lead to illness or even death.[17] The appearance of toxic symptoms varies with the animal species used in the experiment, the route of administration of the compound, and the quantity that has been administered.[42]

Summary of Cucurbitacins

Although Cucurbitacins are highly toxic compounds and often their biological activities are close to their toxic dose level, these compounds possess immense pharmacological potential 48. Apart from their toxic nature cucurbitacins have been proved to possess pharmacological effectiveness against inflammation, cancer, artherosclerosis and diabetes 48. The reports on their toxicity must not overshadow the potential use of these compounds as potent medicinal agents. The chemical modification of various functional groups of these compounds to reduce toxic effects may provide important lead compounds for future research. Various Cucurbitacin analogues have been explored and are well established for toxic nature and their effectiveness against tumor cell lines. In modern drug discovery from medicinal plants, the importance of Cucurbitaceae species has been markedly recognized in empirical control of diabetes 48. The information on absorption, distribution, metabolism and excretion of these compounds is scarce and can be an area of exploration keeping in concern their toxic effects in mammals 48.

  1. Trejo-Moreno C, Méndez-Martínez M, Zamilpa A, et al. Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro. Nutrients. 2018;10(3):276. doi:10.3390/nu10030276 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872694/[][]
  2. Granke LL, Quesada-Ocampo L, Lamour K, Hausbeck MK. Advances in research on Phytophthora capsici on vegetable crops in the United States. Plant Dis 2012; 96: 1588–1600.[]
  3. Gevens AJ, Ando K, Lamour KH, Grumet R, Hausbeck MK. A detached cucumber fruit method to screen for resistance to Phytophthora capsici and effect of fruit age on susceptibility to infection. Plant Dis 2006; 90: 1276–1282.[]
  4. Transcriptome analyses of early cucumber fruit growth identifies distinct gene modules associated with phases of development. Ando K, Carr KM, Grumet R. BMC Genomics. 2012 Oct 2; 13():518. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477022/[]
  5. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][]
  6. Phytochemical and therapeutic potential of cucumber. Mukherjee PK, Nema NK, Maity N, Sarkar BK. Fitoterapia. 2013 Jan; 84():227-36. https://www.ncbi.nlm.nih.gov/pubmed/23098877/[]
  7. Phytochemical and therapeutic potential of cucumber. Mukherjee PK, Nema NK, Maity N, Sarkar BK. Fitoterapia. 2013 Jan; 84():227-36. https://www.sciencedirect.com/science/article/pii/S0367326X12002791[][][][][][][]
  8. Blood sugar lowering potentiality of selected Cucurbitaceae plants of Indian origin. Chandrasekar B, Mukherjee B, Mukherjee SK. Indian J Med Res. 1989 Aug; 90():300-5. https://www.ncbi.nlm.nih.gov/pubmed/2620957/[]
  9. Protective mechanisms of Cucumis sativus in diabetes-related modelsof oxidative stress and carbonyl stress. Heidari H, Kamalinejad M, Noubarani M, Rahmati M, Jafarian I, Adiban H, Eskandari MR. Bioimpacts. 2016; 6(1):33-9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916550/[]
  10. Ramezani M, Rahmani F, Dehestani A. Comparison between the effects of potassium phosphite and chitosan on changes in the concentration of Cucurbitacin E and on antibacterial property of Cucumis sativus. BMC Complementary and Alternative Medicine. 2017;17:295. doi:10.1186/s12906-017-1808-y https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460470/[][]
  11. Kupchan SM, Meshulam H, Sneden AT. New cucurbitacins from Phormium tenax and Marah oreganos. Phytochemistry. 1978;17:767–769. doi: 10.1016/S0031-9422(00)94223-7[]
  12. Kaushik U, Aeri V, Mir SR. Cucurbitacins – an insight into medicinal leads from nature. Pharmacogn Rev. 2015;9(17):12–8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441156/[][][]
  13. Dinan L, Whiting P, Girault JP, Lafont R, Dhadialla TS, Cress DE, et al. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor. Biochem J. 1997;327:643–50[]
  14. Stuppner H, Muller EP. Cucurbitacins with unusual side chains from Picrorhiza kurroa. Phytochem. 1993;37:1483–5[]
  15. Kee HC, Hongtao X. Methods of inducing apoptosis in Cancer treatment by using Cucurbitacins. US2008/0207578A1. 2008 Aug 28[]
  16. Frohne D. London: Wolf; 1983. A coloured Atlas of poisonous plants.[][]
  17. Dinan L, Harmatha J, Lafont R. Chromatographic procedure for the isolation of plant steroids. J Chromatogr A. 2001;935:105–23[]
  18. Jorn G, Inge S, Hans CA. Cucurbitacins in plant food. TemaNord. 2006:556[]
  19. Stuppner H, Muller EP, Wagner H. Cucurbitacins from Picrorhiza kurrooa. Phytochem. 1991;30:305[]
  20. Escandell JM, Kaler P, Recio MC, Sasazuki T, Shirasawa S, Augenlicht L, et al. Activated kRas protects colon cancer cells from Cucurbitacin-induced apoptosis: The role of p53 and p21. Biochem Pharmacol. 2008;76:198–207 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519804/[]
  21. Jayaprakasam B, Seeram NP, Nair MG. Anticancer and anti-inflammatory activities of Cucurbitacins from Cucurbita andreana. Cancer Lett. 2003;189:11–6.[]
  22. Yuan G, Mark LW, Guoqing H, Min Y, Li D. Natural products and anti-inflammatory activity. Asia Pac J Clin Nutr. 2006;15:143–52[]
  23. Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth. Cancer Letters Volume 349, Issue 1, 10 July 2014, Pages 15-25. https://doi.org/10.1016/j.canlet.2014.03.015[][]
  24. Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM. Discovery of JSI-124 (Cucurbitacin I), a selective Janus kinase/ signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Can Res. 2003;63:1270–9[]
  25. Sun J, Blaskovich MA, Jove R, Livingston SK, Coppola D, Sebti SM. Cucurbitacin Q: A selective STAT3 activation inhibitor with potent antitumor activity. Oncogene. 2005;24:3236–45.[]
  26. Dong Y, Lu B, Zhang X, Zhang J, Lai L, Li D, et al. Cucurbitacin E, a tetracyclic triterpenes compound from chinese medicine, inhibits tumor angiogenesis through VEGFR2 mediated JAK2/ STAT3 signaling pathway. Carcinogenesis. 2010;31:2097–104.[]
  27. Duncan KL, Duncan MD, Alley MC, Sausville EA. Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells. Biochem Pharmacol. 1996;52:1553–60[]
  28. Liu T, Zhang M, Zhang H, Sun C, Deng Y. Inhibitory effects of Cucurbitacin B on laryngeal squamous cell carcinoma. Eur Arch Otorhinolaryngol. 2000;265:1225–32[]
  29. Higashio H. Value adding technologies to commodities in vegetable production. Res J Food Agric. 2002;25:8–22.[]
  30. Duangmano S, Dakeng S, Jiratchariyakul W, Suksamra A, Smith DR, Patmasiriwat P. Antiproliferative effects of cucurbitacin B in breast cancer cells: Down-regulation of the c-myc/htert/ telomerase pathway and obstruction of the cell cycle. Int J Mol Sci. 2010;11:5323–38[]
  31. Tannin-Spitz T, Bergman M, Grossman S. Cucurbitacin glucosides: Antioxidant and free-radical scavenging activities. Biochem Biophys Res Commun. 2007;364:181–6[]
  32. Saba AB, Oridupa AO. Search for a novel antioxidant, anti-inflammatory/analgesic or anti-proliferative drug: Cucurbitacins hold the ace. J Med Plants Res. 2010;4:2821–6.[]
  33. Park CS, Lim H, Han KJ, Baek SH, Sohn HO, Lee DW, et al. Inhibition of nitric oxide generation by 23,24-dihydrocucurbitacin D in mouse peritoneal macrophages. J Pharmacol Exp Ther. 2004;309:705–10 http://jpet.aspetjournals.org/content/309/2/705.long[]
  34. Tan MJ, Ye JM, Turner N, Hohen Behrens C, Ke CQ, Tang CP, et al. Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK Pathway. Chem Biol. 2008;15:263–73 https://www.ncbi.nlm.nih.gov/pubmed/18355726[]
  35. Ye JM, Ruderman NB, Kraegen EW. AMP-activated protein kinase and malonyl-CoA: Targets for treating insulin resistance? Drug Disc Today Ther Strateg. 2005;2:157–63[]
  36. Jose´ GA, Omar MC, Fernando B, Robert B, Jose´ PC, Andre´s N, et al. Antidiabetic properties of selected Mexican copalchis of the Rubiaceae family. Phytochem. 2007;68:2087–95[]
  37. Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract. Journal of Young Pharmacists Volume 2, Issue 4, October–December 2010, Pages 365-368. https://doi.org/10.4103/0975-1483.71627[][][]
  38. Anti-encephalitogenic effects of cucumber leaf extract. Journal of Functional Foods. Volume 37, October 2017, Pages 249-262 https://doi.org/10.1016/j.jff.2017.07.060[][][][]
  39. Effect of aqueous extract of Cucumis sativus Linn. fruit in ulcerative colitis in laboratory animals. Asian Pacific Journal of Tropical Biomedicine Volume 2, Issue 2, Supplement, February 2012, Pages S962-S969 https://doi.org/10.1016/S2221-1691(12)60344-X[][]
  40. Balkema-Boomstra AG, Zijlstra S, Verstappen FW, Inggamer H, Mercke PE, Jongsma MA, et al. Role of Cucurbitacin c in resistance to spider mite (Tetranychus urticae) in Cucumber (Cucumis sativus L.) J Chem Ecol. 2003;29:225–35[]
  41. Chen RJ, Jin TR, Chen YC, Chung TY, Yang WH, Tzen JT. Active ingredients in many Chinese medicines promoting blood circulation are Na+/K+-ATPase inhibitors. Acta Pharmacol Sin. 2010;32:141–51[]
  42. Noguchi N, Komuro E, Niki E, Wilson RL. Action of cucurmin as an antioxidant against lipid peroxidation. J Jpn Oil Chem Soc. 1994;43:1045–51[]
  43. Behle RW. Consumption of residue containing Cucurbitacin feeding stimulant and reduced rates of carbaryl insecticide by western corn rootworm (Coleoptera: Chrysomelidae) J Econ Entomol. 2001;94:1428–33[]
  44. Subbiah Method of isolating Cucurbitacin. US1999/5,925,356 Jul. 2011. 1999[]
  45. Metcalf RL, Metcalft RA, Rhodes AM. Cucurbitacins as Kairomones for diabroticite beetles. Proc Natl Acad Sci U S A. 1980;77:3769–72[]
  46. Escandell JM, Recio MC, Manez S, Giner RM, Cerda-Nicolas M, Gil-Benso R, et al. Dihydrocucurbitacin B inhibits delayed type hypersensitivity reactions by suppressing lymphocyte proliferation. J Pharmacol Exp Ther. 2007;322:1261–8.[]
  47. Rıxos JL, Escandell JM, Recio MC. New insight on the bioactivity of Cucurbitacins. In: Atta-Ur-Rahman, editor. Studies in Natural Products Chemistry: Bioactive Natural Products. Vol. 32. Amsterdam: New Insight on the Bioactivity of Cucurbitacins; 2005. pp. 429–69[]
  48. Kaushik U, Aeri V, Mir SR. Cucurbitacins – An insight into medicinal leads from nature. Pharmacognosy Reviews. 2015;9(17):12-18. doi:10.4103/0973-7847.156314 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441156/[][][][]
read more

Is cottage cheese good for you?

cottage cheese

What is cottage cheese

Cottage cheese is believed to have originated because the simple cheese was usually made in cottages from any milk left over after making butter dating back to 1831. Cottage cheese is drained, but not pressed, so some whey remains and the individual curds remain loose. The curd is usually washed to remove acidity, giving sweet-curd cheese. Cottage cheese is not aged or colored. Different styles of cottage cheese are made from milk with different fat levels and in small-curd or large-curd preparations. Pressed cottage cheese becomes hoop cheese, farmer cheese, pot cheese, or queso blanco. The two major types of cottage cheese are small-curd, high-acid cheese made without rennet, and large-curd, low-acid cheese made with rennet. Rennet is a natural complex of enzymes that speeds curdling and keeps the curd that forms from breaking up. Adding rennet shortens the cheese-making process, resulting in a lower acid and larger curd cheese, and reduces the amount of curd poured off with leftover liquid (whey). Sometimes large-curd cottage cheese is called “chunk style.”

Cottage cheese is popular among dieters and some health food devotees. It is a favorite food among bodybuilders, runners, swimmers and weightlifters for its high content of casein protein (a longer-lasting protein) while being relatively low in fat.

Cheeses that are safe to eat in pregnancy

All hard cheeses are safe in pregnancy

You can eat hard cheeses, such as cheddar, parmesan and stilton, even if they’re made with unpasteurized milk. Hard cheeses don’t contain as much water as soft cheeses, so bacteria are less likely to grow in them 1. It’s possible for hard cheese to contain listeria, but the risk is considered to be low 2. Although it’s possible for hard cheeses to contain listeria bacteria, they’re in such low numbers (less than one bacterium per gram of cheese) that they’re not considered to be a health risk to you or your unborn baby. Listeria bacteria can cause an infection called listeriosis.

Hard cheeses are safe to eat during pregnancy, even if they’re made with unpasteurized milk. These include:

  • cheddar
  • edam
  • emmental
  • gouda
  • gruyère
  • jarlsberg
  • parmesan
  • stilton

Soft cheeses that are safe to eat in pregnancy

Other than mold-ripened soft cheeses, all other soft types of cheese are OK to eat, provided they’re made from pasteurized milk.

These include 1:

  • cottage cheese
  • mozzarella
  • feta
  • cream cheese
  • paneer
  • ricotta
  • halloumi
  • goats’ cheese
  • processed cheeses, such as cheese spreads

Cooked soft cheeses that are safe to eat in pregnancy

Thorough cooking should kill any bacteria in cheese, so it should be safe to eat cooked mould-ripened soft cheese, such as brie, camembert and chèvre, and cooked soft blue cheese, such as roquefort or gorgonzola, or dishes that contain them.

  • It’s important to make sure the cheese is thoroughly COOKED until it’s steaming hot all the way through!

Cheeses to avoid in pregnancy

Pregnant women should avoid eating mold-ripened soft cheeses and soft blue-veined cheeses as they can contain higher levels of listeria. Examples of these cheeses include:

  • brie and blue brie
  • camembert
  • chèvre (a type of goats’ cheese). Chèvre is mold-ripened and has a white rind, similar to brie and camembert – you should AVOID all these mold-ripened soft cheeses in pregnancy. This is because soft cheese like this can contain bacteria called Listeria monocytogenes, which can cause listeriosis.
  • Danish blue
  • gorgonzola
  • roquefort

Soft cheeses with white rinds

Don’t eat mold-ripened soft cheese (cheeses with a white rind) such as brie and camembert. This includes mold-ripened soft goats’ cheese, such as chèvre. These cheeses are only safe to eat in pregnancy if they’ve been cooked 2.

Soft blue cheeses

You should also avoid soft blue-veined cheeses such as danish blue, gorgonzola and roquefort. Soft blue cheeses are only safe to eat in pregnancy if they’ve been cooked 2.

It’s advised pregnant women avoid some soft cheeses because they’re less acidic than hard cheeses and contain more moisture, which means they can be an ideal environment for harmful bacteria, such as listeria, to grow in.

Although infection with listeria (listeriosis) is rare, it’s important to take special precautions in pregnancy – even a mild form of the illness in a pregnant woman can lead to miscarriage, stillbirth or severe illness in a newborn baby.

Find out about the symptoms of listeria by reading our article on listeria infection. Listeriosis usually causes flu-like symptoms but can lead to serious problems such as miscarriage or stillbirth, or severe illness in a newborn baby.  If you’re pregnant and showing signs of listeria infection, seek medical help straight away.

Cottage cheese nutrition

A 100g cottage cheese of 4% fat product has about 106 calories, 4.42 g fat (3 g saturated), 4.42 g carbohydrates, and 11.5 g protein. It also contains about 310 mg sodium, 88 mg calcium, and 22 mg cholesterol (see Table 1). 1 cup of cottage cheese (900 mg) each contain over 20% of the Dietary Guidelines for Americans’ recommendation for daily sodium intake 3.

  • Cottage cheese calories is 106 calories per 100 gram cottage cheese
  • Carbs in cottage cheese = 4.42 gram per 100 gram cottage cheese
  • Cottage cheese protein = 11.5 grams per 100 gram cottage cheese

Some manufacturers also produce low-fat (Table 2) and nonfat (Table 3) varieties. A fat-free kind of a similar serving size has 71 calories, 0 g fat (0 g saturated), 4.42 g carbohydrates, and 11.5 g protein.

Table 1. Cottage cheese nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal106
Proteing11.5
Total lipid (fat)g4.42
Carbohydrate, by differenceg4.42
Fiber, total dietaryg0
Sugars, totalg3.54
Minerals
Calcium, Camg88
Iron, Femg0
Potassium, Kmg133
Sodium, Namg310
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU177
Lipids
Fatty acids, total saturatedg3.1
Fatty acids, total monounsaturatedg1.33
Fatty acids, total polyunsaturatedg0
Fatty acids, total transg0
Cholesterolmg22

Ingredients: CULTURED NONFAT MILK, MILK, CREAM, LESS THAN 2% OF: SALT, NONFAT MILK, MALTODEXTRIN, CITRIC ACID, CARRAGEENAN, MONO AND DIGLYCERIDES, LOCUST BEAN GUM, GUAR GUM, NATURAL FLAVORS, CARBON DIOXIDE (TO PRESERVE FRESHNESS), ENZYME.

[Source: United States Department of Agriculture Agricultural Research Service 4]

Table 2. Cottage cheese (Low Fat) nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal76
Proteing8.47
Total lipid (fat)g2.12
Carbohydrate, by differenceg6.78
Fiber, total dietaryg0
Sugars, totalg4.24
Minerals
Calcium, Camg127
Iron, Femg0
Sodium, Namg331
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU339
Vitamin DIU34
Lipids
Fatty acids, total saturatedg1.27
Fatty acids, total transg0
Cholesterolmg13

Ingredients: CULTURED PASTEURIZED GRADE A SKIM MILK, MILK AND CRAM, WHEY, CONTAINS LESS THAN 2% OF MODIFIED FOOD STARCH, SALT, CALCIUM PHOSPHATE, XANTHAN GUM, GUAR GUM NATURAL FLAVOR, VITAMIN A PALMATE, VITAMIN D3.

[Source: United States Department of Agriculture Agricultural Research Service 4]

Table 3. Cottage cheese (Fat Free) nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal71
Proteing11.5
Total lipid (fat)g0
Carbohydrate, by differenceg4.42
Fiber, total dietaryg0
Sugars, totalg3.54
Minerals
Calcium, Camg88
Iron, Femg0
Sodium, Namg398
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU177
Lipids
Fatty acids, total saturatedg0
Fatty acids, total transg0
Cholesterolmg4

Ingredients: CULTURED SKIM MILK, SKIM MILK, WHEY PROTEIN CONCENTRATE, CONTAINS 2% OR LESS OF SALT, GUAR GUM, MONO AND DIGLYCERIDES*, LOCUST BEAN GUM, XANTHAN GUM, NATURAL FLAVORS, ARTIFICIAL COLOR, POTASSIUM SORBATE AND CARBON DIOXIDE (PRESERVATIVES), CARRAGEENAN, POLYSORBATE 80, VITAMIN A PALMITATE, ENZYMES.

[Source: United States Department of Agriculture Agricultural Research Service 4]

Is cottage cheese healthy

Based on the most recent published evidence, April 2018 meta-analyses of randomized controlled trials using 25 prospective studies on dairy products, investigating the relationship between fermented foods and non-transmissible chronic diseases 5 found eating cottage has no health benefit. That review 5 included a range of randomized controlled trials (RCTs) as well as the meta-analyses of randomized controlled trials published by Benatar et al. 6 and de Goede et al. 7, and the systematic reviews of Turner et al. 8 and Labonté et al. 9. These studies investigated LDL “bad” cholesterol, HDL “good” cholesterol, fasting triglycerides, postprandial triglycerides, LDL particle size, apoB, non-HDL cholesterol, cholesterol ratios, inflammatory markers, insulin resistance, blood pressure, and vascular function. The strongest evidence for a beneficial effect was for yogurt on risk factors of type 2 diabetes 5. Although mechanisms explaining this association have not been validated, an increased bioavailability of insulinotropic amino acids and peptides as well as the bacterial biosynthesis of vitamins, in particular vitamin K2, might contribute to this beneficial effect 5. However, the heterogeneity in the design of the studies and the investigated foods impedes a definitive assessment of these associations.

Studies on Cardio-Metabolic Diseases

Drouin-Chartier et al. 10 conducted a comprehensive review of the impact of dairy foods, in particular, of dairy fat, on cardio-metabolic risk. Drouin-Chartier et al. 10 focused their analysis on the potentially detrimental effect of dairy fat on cardio-metabolic risk factors by concluding that there is no apparent risk of potential harmful effects of dairy consumption on a large set of cardio-metabolic variables. Among the products investigated, total dairy, milk, cheese, and yoghurt were discussed, providing additional information on the impact of fermented dairy products on cardio-metabolic health. The authors highlighted that the cholesterol-raising effects of saturated fatty acids are attenuated when provided in complex foods, such as milk, cheese, or yoghurt. Dairy food consumption has neither an impact on low-grade systemic inflammation, nor on insulin resistance or glucose and insulin homeostasis in the short term but may be beneficial in the long term. Furthermore, data from randomized controlled trials that have evaluated the impact of dairy consumption on either blood pressure or vascular function are very consistent in showing mostly no effect.

In summary, an overview of the randomized controlled trials available on the impact of fermented dairy products on cardio-metabolic factors indicate that these products do not differentiate themselves from milk or total dairy in that their impact can be characterized as neutral.

Cardiovascular Diseases

Five meta-analyses have investigated the association between dairy product intake and cardiovascular disease risk in the last five years 11, 12, 13, 14, 15.

The meta-analysis by Qin et al. 14 indicated that total dairy, but not yogurt, may decrease the risk of cardiovascular disease. Alexander et al. 11 indicated that total dairy, milk, yogurt and cheese are not associated with reduced risk of cardiovascular disease. Moderate evidence that higher intake of cheese is associated with a weak reduction of risk of cardiovascular disease was reported by Chen et al. 16. Moderate evidence for a weak reduction of risk of cardiovascular disease for fermented dairy, but not for dairy, milk, cheese, or yogurt was reported by Guo et al. 12. The same authors also reported moderate evidence for a weak reduction of risk of mortality for fermented dairy, but not for dairy, milk, cheese, or yogurt 12. Finally, the meta-analysis by O’Sullivan et al. 13 indicated moderate evidence that total dairy, milk and cheese do not modify the risk of cardiovascular disease mortality.

In their systematic review, Drouin-Chartier et al. 17 concluded that the association between the consumption of fermented dairy and cardiovascular disease risk is based on very low-quality evidence and thus remains uncertain at this point.

Taken together, none of the meta-analyses reported a detrimental effect of dairy products, including all fermented dairy products investigated. A neutral effect of yogurt was demonstrated in all four meta-analyses in which this product was investigated, whereas one out of five meta-analyses reported a beneficial effect of cheese consumption. On the other hand, the data from two meta-analyses on fermented dairy provided evidence for a beneficial effect of this product category. In conclusion, these meta-analyses provide weak evidence that fermented foods may have a beneficial effect on cardiovascular disease, although the data remain weak and inconsistent.

Coronary Heart Disease (CHD)/Coronary Artery Disease (CAD)

Four meta-analyses have investigated the association between dairy products and Coronary Heart Disease/Coronary Artery Disease risk in the last five years 1611, 12, 14. Moderate evidence that higher intake of cheese is associated with a moderately reduced risk of Coronary Heart Disease was reported by Chen et al. 16. No evidence for a reduction of risk of Coronary Heart Disease was found for dairy, milk, fermented dairy, cheese, or yogurt 12. Moderate evidence suggesting that cheese consumption, in particular, at higher servings, but not total dairy, milk or yoghurt, may be associated with a moderate reduction of risk of Coronary Heart Disease was reported by Alexander et al. 11. Finally, moderate evidence, reported by Qin et al. 14, suggests that cheese, but not total dairy or yogurt, may moderately decrease the risk of Coronary Heart Disease.

In their systematic review, Drouin-Chartier et al. 17 concluded that there is moderate but consistent evidence for a neutral association between yogurt consumption and Coronary Artery Disease risk. The same authors also concluded that the association between the consumption of fermented dairy and the risk of Coronary Artery Disease remains uncertain because only evidence of insufficient quality is available.

Taken together, moderate evidence for a moderate reduction of risk of Coronary Heart Disease was associated with the consumption of cheese in three out of four meta-analyses, whereas the other analyses, including yogurt, milk and dairy, indicated a neutral effect.

Stroke

Four meta-analyses have investigated the association between dairy product consumption and stroke risk in the last five years 11, 18, 19, 20, 14. The analysis by Alexander et al. 11 suggested that there is moderate evidence that cheese consumption, but not milk, may be associated with a moderate reduction in the risk of stroke, whereas total dairy consumption may be associated with a reduction in the risk of stroke. The analysis by de Goede et al. 18 indicated moderate evidence for a weak reduction in the risk of stroke with consumption of milk and >25 g/day cheese. Qin et al. 14 indicated that total dairy may decrease the risk of stroke and showed moderate evidence that cheese, but not yoghurt, may weakly decrease the risk of stroke. Also, Hu et al. 20 showed moderate evidence that total dairy, including fermented milk, but not milk or non-fermented milk, may moderately decrease the risk of stroke. Finally, the study by Hu et al. 20 suggested that there is moderate evidence that cheese intake may weakly decrease the risk of stroke.

In their systematic review, Drouin-Chartier et al. 17 suggested that there is moderate-quality evidence that the consumption of fermented dairy is associated with a reduced risk of stroke (see Table 4). They further concluded that the available meta-analysis on yogurt has a relatively good quality score, further suggesting that yogurt consumption is not associated with the risk of stroke; this was based on moderate-quality evidence.

Taken together, none of the dairy products, including fermented dairy products, are associated with a detrimental effect on stroke. Moderate evidence for a weak to moderate effect of fermented dairy products, in particular, cheese, is indicated by these meta-analyses, although these effects are inconsistently associated with the fermentation process—yogurt was found to have a neutral effect when investigated in the product-specific study.

Hypertension

Two meta-analyses have investigated the association between dairy products and hypertension risk in the last five years 21, 22. In addition, one meta-analysis, integrating 15 randomized controlled trials evaluating the impact of fermented dairy products on hypertension, was published by Usinger et al. 23.

The study by Soedamah-Muthu et al. 22 suggested that total dairy and milk, but not yogurt, total fermented dairy or cheese may moderately contribute to the prevention of hypertension. Also, the report by Ralston et al. 21 provided moderate evidence for a moderate effect of fluid dairy foods (including milk and yoghurt), but not cheese, on blood pressure in subjects with elevated blood pressure.

In the Cochrane review of randomized controlled trials on the impact of fermented milk on hypertension, Usinger et al. 23 suggested a modest overall effect of fermented milk on blood pressure. However, the evidence was evaluated as weak, in light of the fact that an effect of fermented milk was found on systolic blood pressure (BP), but not on diastolic blood pressure.

The included studies were of variable quality as well as heterogeneous, and the findings do not support the use of fermented milk as an anti-hypertensive treatment or as a lifestyle intervention to reduce blood pressure.

In their systematic review, Drouin-Chartier et al. 17 concluded that there is no significant association between the consumption of fermented dairy and the risk of hypertension. Of note, Drouin-Chartier et al. 17 commented on an additional published study on this topic 24, which reported an inverse association between the consumption of fermented dairy and the risk of hypertension. This study has an important weighting (n = 2340) relative to data from the meta-analysis by Soedamah-Muthu et al. 22 (n = 7641) and is likely to modify pooled risk estimates. In this context, Drouin-Chartier et al. 17 suggested that moderate-quality evidence supports a neutral association between the consumption of fermented dairy and the risk of hypertension, with the need for further studies on the topic to yield better quality evidence. Regarding yogurt and the risk of hypertension, moderate-quality evidence was suggested by Drouin-Chartier et al. 17 that yogurt consumption is not associated with the risk of hypertension (Table 4).

Taken together, none of the dairy products, including fermented dairy products, are associated with an increased risk of hypertension. Half of the studies reported weakly beneficial effects but the results are inconsistent.

Myocardial Infarction (Heart Attack)

No meta-analysis is available that summarizes studies characterizing the association of fermented dairy products and myocardial infarction (heart attack) risk.

Type 2 Diabetes Mellitus

Five meta-analyses have investigated the associations between fermented dairy products and type 2 diabetes mellitus risk in the last five years 25, 26, 27, 28, 29.

The meta-analysis by Gijsbers et al. 30 provided moderate evidence that the intake of dairy foods, yogurt and fermented dairy, but not cheese or milk, moderately decreases type 2 diabetes mellitus risk. The study by Chen et al. 25 showed moderate evidence that higher intake of yogurt is associated with a moderately-reduced risk of type 2 diabetes mellitus, whereas total dairy is not appreciably associated with the incidence of type 2 diabetes mellitus. Aune et al. 27 indicated that dairy products, but not milk, may be associated with a decrease in the risk of type 2 diabetes mellitus. Also, moderate evidence suggested that yogurt at higher doses may moderately decrease the risk of type 2 diabetes mellitus. Finally, the same authors reported moderate evidence that cheese, but not cottage cheese, may weakly decrease the risk of type 2 diabetes mellitus, as well as weak evidence that fermented milk may moderately decrease the risk of type 2 diabetes mellitus 5. The fourth meta-analysis by Gao et al. 28 showed moderate evidence suggesting that the intake of dairy products, cheese and high doses of yogurt, but not milk or fermented dairy, moderately decrease type 2 diabetes mellitus risk. Finally, Tong et al. 29 indicated that total dairy may reduce the risk of type 2 diabetes mellitus, whereas moderate evidence suggests that yogurt, but not whole milk, may moderately reduce the risk of type 2 diabetes mellitus.

In their systematic review, Drouin-Chartier et al. 17 concluded that the consumption of fermented dairy does not appear to be associated with the risk of type 2 diabetes mellitus. This statement was based on moderate-quality evidence, because the three meta-analyses available relied on almost the same pools of prospective cohort studies (see Table 4). On the other hand, the same authors concluded that the five meta-analyses regarding the association between yogurt intake and the risk of type 2 diabetes mellitus reported consistent results, suggesting that there is high-quality evidence that supports an inverse association between the intake of yogurt and the risk of type 2 diabetes mellitus.

Taken together, these meta-analyses provide evidence for a positive impact of fermented dairy, in particular yogurt, on type 2 diabetes mellitus risk.

Table 4. Evaluation of the impact of dairy products on cardio-metabolic factors and diseases (intervention studies and prospective studies).

Total DairyMilkCheeseYogurt
Prospective studies 17
CVDNeutralUncertainNeutralNeutral
CAD/CHDNeutralNeutralNeutralNeutral
StrokeFavorableNeutralFavorableNeutral
HypertensionFavorableFavorableNeutralNeutral
MetSFavorableFavorableUncertainUncertain
T2DMFavorableNeutralFavorableFavorable
Interventional studies randomized controlled trials 10
LDL cholesterolNo effectNo effectNo effectNo effect
HDL cholesterolNo effectUncertainUncertainNo effect
Fasting TGsNo effectUncertainNo effectNo effect
Postprandial TGsUndeterminedNo effectNo effectUndetermined
LDL sizeUndeterminedNo effectUndeterminedUndetermined
apoBUndeterminedNo effectNo effectUndetermined
Non-HDL cholesterolUndeterminedUndeterminedUndeterminedUndetermined
Cholesterol ratiosUndeterminedNo effectNo effectReduced
InflammationNo effectNo effectUndeterminedNo effect
Insulin resistanceUncertainNo effectNo effectNo effect
Blood pressureNo effectNo effectUndeterminedNo effect
Vascular functionNo effectNo effectUndeterminedNo effect

Notes: apoB: apolipoprotein B; CAD: coronary artery disease; CHD: coronary heart disease; CVD: cardiovascular disease; HDL: high-density lipoprotein  “good” cholesterol; LDL: low-density lipoprotein “bad” cholesterol; MetS: Metabolic Syndrome; T2DM: Type 2 Diabetes Mellitus; TG: triglyceride.

[Source 5]

Metabolic Syndrome (Metabolic Syndrome X)

One meta-analysis has investigated the association between dairy products and metabolic syndrome risk in the last five years 31.

This meta-analysis indicated that dairy intake may be inversely associated with the incidence and prevalence of metabolic syndrome. Also, weak evidence from cross-sectional studies suggests that dairy, milk and cheese, but not yogurt, may moderately decrease the incidence of diabetes.

In their systematic review, Drouin-Chartier et al. 17 judged the quality of the evidence relating yogurt intake to the incidence of metabolic syndrome to be very low, and thus, the association remains uncertain.

Taken together, none of the dairy products, including fermented dairy products, are associated with an increased or a decreased risk of metabolic syndrome.

Obesity

One meta-analysis has investigated the association between dairy products and metabolic obesity risk in the last five years 32.

This meta-analysis 32 indicated, with weak to moderate evidence, that yogurt consumption weakly decreases weight gain, waist circumference, risk of being overweight, and risk of abdominal obesity. The study also provided moderate evidence that cheese consumption weakly increases weight gain. In addition, dairy was negatively associated with weight gain, waist circumference, risk of being overweight and risk of abdominal obesity. Finally, milk consumption was negatively associated with waist circumference.

Taken together, yogurt might be beneficial preventing obesity 32. However, no significant association for yogurt consumption was observed for most of the endpoints related to obesity when comparing the highest versus the lowest categories of consumption. Further, the overall interpretation of the results is limited by heterogeneous risk estimates. The level of evidence for impacts of fermented dairy products on obesity risk is limited, and further studies are needed.

Summary of Studies Involving Cardio-metabolic Diseases

Dairy food consumption has neither an impact on low-grade systemic inflammation, nor on insulin resistance or glucose and insulin homeostasis in the short term but may be beneficial in the long term. Furthermore, data from randomized controlled trials that have evaluated the impact of dairy consumption on either blood pressure or vascular function are very consistent in showing mostly no effect. The consumption of fermented foods in the context of particular indications, such as yogurt intake and diabetes or cheese intake and stroke, can only be recommended on the basis of weak and inconsistent evidence 5.

In summary, an overview of the randomized controlled trials available on the impact of fermented dairy products on cardio-metabolic factors indicate that these products do not differentiate themselves from milk or total dairy in that their impact can be characterized as neutral 5.

Studies on Cancer

Two meta-analyses from the last five years investigated the association between dairy products and colorectal cancer risk 33, 34. The first meta-analysis showed that milk and total dairy products are associated with a significant reduction in colon cancer risk, whereas cheese, yoghurt, fermented milk and fermented dairy have neutral effects 33. Ralston et al. 34 later confirmed these findings by reporting a significant inverse association between the consumption of non-fermented dairy products and the risk of colorectal cancer, but no association between the consumption of fermented milk and cheese and colorectal cancer risk.

There is no evidence for a beneficial or detrimental effect of fermented dairy products on colorectal cancer. The potential beneficial effects of dairy products regarding colorectal cancer are thus unlikely to be attributed to the fermentation process.

One meta-analysis investigated the association between dairy products and pancreatic cancer risk that was published in the last five years 35. Intakes of cheese, cottage cheese, yogurt, as well as milk, were not associated with pancreatic cancer risk. There is no evidence for a beneficial or detrimental effect of fermented dairy products on pancreatic cancer.

Two meta-analyses investigated the association between dairy products and gastric cancer risk 36, 37. None of these analyses demonstrated a significant association between the intake of cheese and yoghurt, and gastric cancer risk. Of note, the results of cohort studies, but not case-control studies, suggested that total dairy intake might be related to the reduction of gastric cancer risk 38, whereas the results of case-control studies, but not cohort studies, provided weak evidence for an increased risk 36.

There is no evidence for a beneficial or detrimental effect of fermented dairy products on gastric cancer. The potential effects of dairy products on gastric cancer are thus unlikely to be attributed to the fermentation process.

One meta-analysis from the last five years, summarizing 19 cohort and case-control studies, investigated the associations between fermented dairy products and ovarian cancer risk 39. This study concluded that milk and yoghurt intake has no association with an increased risk of ovarian cancer. There is no evidence for a beneficial or detrimental effect of fermented dairy products on ovarian cancer.

One meta-analysis from the last five years has summarized cohort and case-control studies in order to investigate the associations between fermented dairy products and lung cancer risk 40. Weak evidence from two cohort studies was available for a protective effect of cheese, but this effect was not found in the overall analysis of all studies that included eight case-control studies. In addition, no effects were observed for dairy, milk and yogurt. Taken together, there is no evidence for a beneficial or detrimental effect of fermented dairy products on lung cancer.

No meta-analysis is available that summarizes the impact of dairy products or fermented dairy products on other types of cancer. Also, to our knowledge, no individual study has been published focusing on the effects of fermented dairy product intake on additional types of cancer whose results would justify a critical appraisal in this report.

Summary of Studies Involving Cancer

In their review, Thorning et al. 41 concluded that, according to the World Cancer Research Fund reports and the latest meta-analyses, (i) consumption of milk and dairy products probably protects against colorectal, bladder, gastric and breast cancers, (ii) dairy intake does not seem to be associated with risk of pancreatic, ovarian or lung cancer; and (iii) the evidence for prostate cancer risk is inconsistent.

  1. Are hard cheeses safe to eat during pregnancy? https://www.nhs.uk/chq/Pages/are-hard-cheeses-safe-to-eat-during-pregnancy.aspx[][]
  2. Foods to avoid in pregnancy. https://www.nhs.uk/conditions/pregnancy-and-baby/foods-to-avoid-pregnant/[][][]
  3. ChooseHealthLA. Salt. http://www.choosehealthla.com/eat/salt/[]
  4. United States Department of Agriculture Agricultural Research Service. USDA Branded Food Products Database. https://ndb.nal.usda.gov/ndb/search/list[][][]
  5. Fermented Food and Non-Communicable Chronic Diseases: A Review. Nutrients. 2018 Apr; 10(4): 448. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946233/[][][][][][][][]
  6. Benatar J.R., Sidhu K., Stewart R.A. Effects of high and low fat dairy food on cardio-metabolic risk factors: A meta-analysis of randomized studies. PLoS ONE. 2013;8:e76480 doi: 10.1371/journal.pone.0076480 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795726/[]
  7. De Goede J., Geleijnse J.M., Ding E.L., Soedamah-Muthu S.S. Effect of cheese consumption on blood lipids: A systematic review and meta-analysis of randomized controlled trials. Nutr. Rev. 2015;73:259–275. doi: 10.1093/nutrit/nuu060 https://www.ncbi.nlm.nih.gov/pubmed/26011901[]
  8. Turner K.M., Keogh J.B., Clifton P.M. Dairy consumption and insulin sensitivity: A systematic review of short- and long-term intervention studies. Nutr. Metab. Cardiovasc. Dis. 2015;25:3–8. doi: 10.1016/j.numecd.2014.07.013 https://www.ncbi.nlm.nih.gov/pubmed/25156891[]
  9. Labonté M.E., Couture P., Richard C., Desroches S., Lamarche B. Impact of dairy products on biomarkers of inflammation: A systematic review of randomized controlled nutritional intervention studies in overweight and obese adults. Am. J. Clin. Nutr. 2013;97:706–717. doi: 10.3945/ajcn.112.052217 https://www.ncbi.nlm.nih.gov/pubmed/23446894[]
  10. Drouin-Chartier J.-P., Côté J.A., Labonté M.-È., Brassard D., Tessier-Grenier M., Desroches S., Couture P., Lamarche B. Comprehensive Review of the Impact of Dairy Foods and Dairy Fat on Cardiometabolic Risk. Adv. Nutr. Int. Rev. J. 2016;7:1041–1051. doi: 10.3945/an.115.011619 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105034/[][][]
  11. Alexander D.D., Bylsma L.C., Vargas A.J., Cohen S.S., Doucette A., Mohamed M., Irvin S.R., Miller P.E., Watson H., Fryzek J.P. Dairy consumption and CVD: A systematic review and meta-analysis. Br. J. Nutr. 2016;115:737–750. doi: 10.1017/S0007114515005000[][][][][][]
  12. Guo J., Astrup A., Lovegrove J.A., Gijsbers L., Givens D.I., Soedamah-Muthu S.S. Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: Dose-response meta-analysis of prospective cohort studies. Eur. J. Epidemiol. 2017;32:269–287. doi: 10.1007/s10654-017-0243-1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437143/[][][][][]
  13. O’Sullivan T.A., Hafekost K., Mitrou F., Lawrence D. Food sources of saturated fat and the association with mortality: A meta-analysis. Am. J. Public Health. 2013;103:e31–e42. doi: 10.2105/AJPH.2013.301492 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966685/[][]
  14. Qin L.Q., Xu J.Y., Han S.F., Zhang Z.L., Zhao Y.Y., Szeto I.M. Dairy consumption and risk of cardiovascular disease: An updated meta-analysis of prospective cohort studies. Asia Pac. J. Clin. Nutr. 2015;24:90–100[][][][][][]
  15. Chen M., Li Y., Sun Q., Pan A., Manson J.E., Rexrode K.M., Willett W.C., Rimm E.B., Hu F.B. Dairy fat and risk of cardiovascular disease in 3 cohorts of US adults. Am. J. Clin. Nutr. 2016;104:1209–1217. doi: 10.3945/ajcn.116.134460 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081717/[]
  16. Chen G.-C., Wang Y., Tong X., Szeto I.M.Y., Smit G., Li Z.-N., Qin L.-Q. Cheese consumption and risk of cardiovascular disease: A meta-analysis of prospective studies. Eur. J. Nutr. 2017;56:2565–2575. doi: 10.1007/s00394-016-1292-z[][][]
  17. Drouin-Chartier J.-P., Brassard D., Tessier-Grenier M., Côté J.A., Labonté M.-È., Desroches S., Couture P., Lamarche B. Systematic Review of the Association between Dairy Product Consumption and Risk of Cardiovascular-Related Clinical Outcomes. Adv. Nutr. Int. Rev. J. 2016;7:1026–1040. doi: 10.3945/an.115.011403 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105032/[][][][][][][][][][]
  18. De Goede J., Soedamah-Muthu S.S., Pan A., Gijsbers L., Geleijnse J.M. Dairy Consumption and Risk of Stroke: A Systematic Review and Updated Dose-Response Meta-Analysis of Prospective Cohort Studies. J. Am. Heart Assoc. 2016;5:e002787. doi: 10.1161/JAHA.115.002787 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889169/[][]
  19. Gholami F., Khoramdad M., Esmailnasab N., Moradi G., Nouri B., Safiri S., Alimohamadi Y. The effect of dairy consumption on the prevention of cardiovascular diseases: A meta-analysis of prospective studies. J. Cardiovasc. Thorac. Res. 2017;9:1–11. doi: 10.15171/jcvtr.2017.01 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402021/[]
  20. Hu D., Huang J., Wang Y., Zhang D., Qu Y. Dairy foods and risk of stroke: A meta-analysis of prospective cohort studies. Nutr. Metab. Cardiovasc. Dis. 2014;24:460–469. doi: 10.1016/j.numecd.2013.12.006 https://www.ncbi.nlm.nih.gov/pubmed/24472634[][][]
  21. Ralston R.A., Lee J.H., Truby H., Palermo C.E., Walker K.Z. A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods. J. Hum. Hypertens. 2012;26:3–13. doi: 10.1038/jhh.2011.3 https://www.ncbi.nlm.nih.gov/pubmed/21307883[][]
  22. Soedamah-Muthu S.S., Verberne L.D., Ding E.L., Engberink M.F., Geleijnse J.M. Dairy consumption and incidence of hypertension: A dose-response meta-analysis of prospective cohort studies. Hypertension. 2012;60:1131–1137. doi: 10.1161/HYPERTENSIONAHA.112.195206 http://hyper.ahajournals.org/content/60/5/1131.long[][][]
  23. Usinger L., Reimer C., Ibsen H. Fermented milk for hypertension. Cochrane Database Syst. Rev. 2012 doi: 10.1002/14651858.CD008118.pub2 http://cochranelibrary-wiley.com/doi/10.1002/14651858.CD008118.pub2/full[][]
  24. Wang H., Fox C.S., Troy L.M., Mckeown N.M., Jacques P.F. Longitudinal association of dairy consumption with the changes in blood pressure and the risk of incident hypertension: The Framingham Heart Study. Br. J. Nutr. 2015;114:1887–1899. doi: 10.1017/S0007114515003578 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635606/[]
  25. Chen M., Sun Q., Giovannucci E., Mozaffarian D., Manson J.E., Willett W.C., Hu F.B. Dairy consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis. BMC Med. 2014;12:215 doi: 10.1186/s12916-014-0215-1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243376/[][]
  26. Gijsbers L., Ding E.L., Malik V.S., de Goede J., Geleijnse J.M., Soedamah-Muthu S.S. Consumption of dairy foods and diabetes incidence: A dose-response meta-analysis of observational studies. Am. J. Clin. Nutr. 2016;103:1111–1124. doi: 10.3945/ajcn.115.123216 https://www.ncbi.nlm.nih.gov/pubmed/26912494[]
  27. Aune D., Norat T., Romundstad P., Vatten L.J. Dairy products and the risk of type 2 diabetes: A systematic review and dose-response meta-analysis of cohort studies. Am. J. Clin. Nutr. 2013;98:1066–1083. doi: 10.3945/ajcn.113.059030 https://www.ncbi.nlm.nih.gov/pubmed/23945722[][]
  28. Gao D., Ning N., Wang C., Wang Y., Li Q., Meng Z., Liu Y., Li Q. Dairy products consumption and risk of type 2 diabetes: Systematic review and dose-response meta-analysis. PLoS ONE. 2013;8:e73965 doi: 10.1371/journal.pone.0073965 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785489/[][]
  29. Tong X., Dong J.Y., Wu Z.W., Li W., Qin L.Q. Dairy consumption and risk of type 2 diabetes mellitus: A meta-analysis of cohort studies. Eur. J. Clin. Nutr. 2011;65:1027–1031. doi: 10.1038/ejcn.2011.62 https://www.ncbi.nlm.nih.gov/pubmed/21559046[][]
  30. Gijsbers L., Ding E.L., Malik V.S., de Goede J., Geleijnse J.M., Soedamah-Muthu S.S. Consumption of dairy foods and diabetes incidence: A dose-response meta-analysis of observational studies. Am. J. Clin. Nutr. 2016;103:1111–1124. doi: 10.3945/ajcn.115.123216[]
  31. Kim Y., Je Y. Dairy consumption and risk of metabolic syndrome: A meta-analysis. Diabet. Med. 2016;33:428–440. doi: 10.1111/dme.12970 https://www.ncbi.nlm.nih.gov/pubmed/26433009[]
  32. Schwingshackl L., Hoffmann G., Schwedhelm C., Kalle-Uhlmann T., Missbach B., Knüppel S., Boeing H. Consumption of Dairy Products in Relation to Changes in Anthropometric Variables in Adult Populations: A Systematic Review and Meta-Analysis of Cohort Studies. PLoS ONE. 2016;11:e0157461 doi: 10.1371/journal.pone.0157461 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911011/[][][]
  33. Aune D., Lau R., Chan D.S., Vieira R., Greenwood D.C., Kampman E., Norat T. Dairy products and colorectal cancer risk: A systematic review and meta-analysis of cohort studies. Ann. Oncol. 2012;23:37–45. doi: 10.1093/annonc/mdr269 https://www.ncbi.nlm.nih.gov/pubmed/21617020[][]
  34. Ralston R.A., Truby H., Palermo C.E., Walker K.Z. Colorectal cancer and nonfermented milk, solid cheese, and fermented milk consumption: A systematic review and meta-analysis of prospective studies. Crit. Rev. Food Sci. Nutr. 2014;54:1167–1179. doi: 10.1080/10408398.2011.629353 https://www.ncbi.nlm.nih.gov/pubmed/24499149[][]
  35. Genkinger J.M., Wang M., Li R., Albanes D., Anderson K.E., Bernstein L., van den Brandt P.A., English D.R., Freudenheim J.L., Fuchs C.S., et al. Dairy products and pancreatic cancer risk: A pooled analysis of 14 cohort studies. Ann. Oncol. 2014;25:1106–1115. doi: 10.1093/annonc/mdu019 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037857/[]
  36. Sun Y., Lin L.J., Sang L.X., Dai C., Jiang M., Zheng C.Q. Dairy product consumption and gastric cancer risk: A meta-analysis. World J. Gastroenterol. 2014;20:15879–15898. doi: 10.3748/wjg.v20.i42.15879 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229556/[][]
  37. Tian S.B., Yu J.C., Kang W.M., Ma Z.Q., Ye X., Cao Z.J. Association between dairy intake and gastric cancer: A meta-analysis of observational studies. PLoS ONE. 2014;9:e101728 doi: 10.1371/journal.pone.0101728 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090187/[]
  38. Guo Y., Shan Z., Ren H., Chen W. Dairy consumption and gastric cancer risk: A meta-analysis of epidemiological studies. Nutr. Cancer. 2015;67:555–568. doi: 10.1080/01635581.2015.1019634 https://www.ncbi.nlm.nih.gov/pubmed/25923921[]
  39. Liu J., Tang W., Sang L.X., Dai X., Wei D., Luo Y., Zhang J. Milk, Yogurt, and Lactose Intake and Ovarian Cancer Risk: A Meta-Analysis. Nutr. Cancer. 2015;67:68–72. doi: 10.1080/01635581.2014.956247 https://www.ncbi.nlm.nih.gov/pubmed/25298278[]
  40. Yang Y., Wang X., Yao Q., Qin L., Xu C. Dairy Product, Calcium Intake and Lung Cancer Risk: A Systematic Review with Meta-Analysis. Sci. Rep. 2016;6:20624. doi: 10.1038/srep20624 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753428/[]
  41. Thorning T.K., Raben A., Tholstrup T., Soedamah-Muthu S.S., Givens I., Astrup A. Milk and dairy products: Good or bad for human health? An assessment of the totality of scientific evidence. Food Nutr. Res. 2016;60:32527. doi: 10.3402/fnr.v60.32527 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122229/[]
read more

Is almond butter healthy?

almond butter

What is almond butter

Almond butter is a food paste made from almonds. Almond butter may be crunchy or smooth, and is generally “stir” (susceptible to oil separation) or “no-stir” (emulsified). Almond butter may be either raw or roasted, describing the almonds themselves prior to grinding. It is recommended that almond butter be refrigerated once opened to prevent spoilage and oil separation. Generally, nut/seed butters contain generous amounts of phytochemicals that may be protective against colon, prostate, and breast cancer 1. According to Jiang et al. 2, the relative risk of developing diabetes was reduced 27% in those who ate nuts five or more times per week compared with those who rarely or never ate nuts. Nutritional property of some of the nut/seed butter is presented in Table 6. Raw nuts have primarily 1 of the 2 unsaturated types (except coconut and palm kernels), thus leads healthful source of fatty acids for the production of lower cholesterol level foods. At present different plant based butters/spreads are available in the market. For example peanut butter, almond butter, cashew butter, pumpkin seed butter, pistachio butter, soy butter, sunflower and sesame butter. The term plant based (Nut/Seed) butter refers to a product that contains at least 90 % nut/seed ingredients whereas, the spread refers to a spreadable product having at least 40 % nut ingredients which can be added in various forms, e.g. as nuts, a paste and/or a slurry 3.

The dairy butter is a water-in-oil emulsion, i.e. >80 % fat with tiny water droplets, perhaps some solids-not-fat and with/without salt 4 (see Table 5 below). However, animal foods such as butter are rich in saturated fat. Butter with and without salt contains 55 ± 2 g/100 g of saturated fat and 222 ± 2 mg/100 g cholesterol 5.

Due to the mounting health concerns regarding the consumption of dairy butter because of its high saturated fat content has raised the need to search for an alternative plant based butters viz., nut butters and seed butters. Nuts and seeds are nutrient dense foods and have been a regular constituent of mankind’s diet since pre-agricultural times 6. Nuts and seeds are generally consumed as snack food in roasted form as they are of good taste, handy and easy to eat. But, recently with the advent of new technologies, myriad varieties of nut and seed based snacks and processed products have arrived in the market out of which the form of butter gained more popularity.

Evidence suggests that nut consumption, including peanuts, protects against not only coronary heart disease (coronary artery disease) but also against diabetes and the coronary heart disease (coronary artery disease) associated with diabetes, and other metabolic syndrome diseases, notably gallstone disease 7. In one of the largest studies to date about the health benefits of nuts, researchers analyzed data from more than 210,000 health professionals over as many as 32 years. They found that, compared with those who never or almost never ate nuts, people who ate one ounce of nuts five or more times per week had a 14% lower risk of cardiovascular disease and a 20% lower risk of coronary heart disease during the study period. Both walnuts and peanuts were linked with lower disease risk, the study found. No heart benefits were associated with eating peanut butter—which could be because people tend to pair peanut butter with unhealthy foods or because peanut butter is often mixed with salt and sweeteners, possibly canceling out the positive health benefits of the peanuts, according to an editorial accompanying the study.

The form of butter is one of the healthy way of integrating nuts and seeds into your regular diet. Nut and seed butters are generally prepared by roasting, grinding and refrigerated to consume it when it is still fresh. During this process it is imperative to retain the nutritional properties of these nuts and seeds in order to reap the benefits of the fresh nuts and seeds in the form of butter as well. Proper care is needed to minimize the conversion of healthful components in to unhealthy components during processing and further storage. Roasting temperature, temperatures during grinding and storage are the vital factors to be considered in order to have healthy and nutritious plant based butters.

The type of nuts you choose to eat probably doesn’t matter much. Most nuts appear to be generally healthy, though some may have more heart-healthy nutrients than others. For example, walnuts contain high amounts of omega-3 fatty acids.

Almonds, macadamia nuts, hazelnuts and pecans are other nuts that appear to be quite heart healthy. And peanuts — which are technically not a nut, but a legume, like beans — seem to be relatively healthy.

Keep in mind, you could end up canceling out the heart-healthy benefits of nuts if they’re covered with chocolate, sugar or salt.

What’s in nuts that might make them heart healthy?

Besides being packed with protein, most nuts contain at least some of these heart-healthy substances:

  • Unsaturated fats. It’s not entirely clear why, but it’s thought that the “good” fats in nuts — both monounsaturated and polyunsaturated fats — lower bad cholesterol levels.
  • Omega-3 fatty acids. Omega-3 fatty acids are found in many kinds of fish, but many nuts are also rich in omega-3 fatty acids. Omega-3s are a healthy form of fatty acids that seem to help your heart by, among other things, preventing dangerous heart rhythms that can lead to heart attacks.
  • Fiber. All nuts contain fiber, which helps lower your cholesterol. Fiber makes you feel full, so you eat less. Fiber is also thought to play a role in preventing type 2 diabetes.
  • Vitamin E. Vitamin E may help stop the development of plaques in your arteries, which can narrow them. Plaque development in your arteries can lead to chest pain, coronary artery disease or a heart attack.
  • Plant sterols. Some nuts contain plant sterols, a substance that can help lower your cholesterol. Plant sterols are often added to products like margarine and orange juice for additional health benefits, but sterols occur naturally in nuts.
  • L-arginine. Nuts are also a source of l-arginine, which is a substance that may help improve the health of your artery walls by making them more flexible and less prone to blood clots that can block blood flow.

Figure 1. Almond butter

almond butter

What is almond

The almond (Prunus dulcis, syn. Prunus amygdalus) is a species of tree native to the Middle East, the Indian subcontinent and North Africa 8. The almond fruit measures 3.5–6 cm (1–2 in) long. In botanical terms, almond fruit is not a nut but a drupe. The almond fruit drupe, consisting of an outer hull and a hard shell with the seed, which is not a true nut, inside. In botany, a drupe (stone fruits) is an indehiscent fruit in which an outer fleshy part (exocarp or skin; and mesocarp or flesh) surrounds a single shell (the pit or stone) of hardened endocarp with a seed (kernel) inside 9. The definitive characteristic of a drupe is that the hard, “lignified” stone (or pit) is derived from the ovary wall of the flower—in an aggregate fruit composed of small, individual drupes (such as a raspberry) (see Figure 1). Some flowering plants that produce drupes are coffee, jujube, mango, olive, most palms (including date, sabal, coconut and oil palms), pistachio, white sapote, cashew and all members of the genus Prunus, including the almond (in which the mesocarp is somewhat leathery), apricot, cherry, damson, nectarine, peach, and plum.

Shelling almonds refers to removing the shell to reveal the seed. Almonds are sold shelled or unshelled. Blanched almonds are shelled almonds that have been treated with hot water to soften the seedcoat, which is then removed to reveal the white embryo.

  • Almond is naturally gluten free.

Figure 2. Drupe fruit diagram

Drupe_fruit_diagram

Figure 3. Almond fruit (raw) green

almond fruit - green

Figure 4. Almonds in tough outer shell

almonds in shell

Figure 5. Almonds raw and shelled

Almond-Nuts-Shelled-Raw

Figure 6. Almonds blanched

almonds blanched

Almond butter nutrition

Almond butter is high in monounsaturated fats, calcium, potassium, iron and manganese. Almond butter is considered a good source of riboflavin, phosphorus, and copper and an excellent source of vitamin E, magnesium, and fiber. Almond butter also provides dietary protein.

Almond butter is an alternative to peanut butter for those with peanut allergies or who dislike the taste of peanuts. Almond butter contains significantly more fiber, calcium, potassium, iron, and manganese than peanut butter and about half the saturated fat, although a slightly higher total fat content. Almonds are not legumes whereas peanuts are, so almond butter can be consumed by those looking to avoid legumes.

Plain raw almond butter calories without added salt is about 614 calories per 100 gram.

Carbs in almond butter is 18.82 gram per 100 gram.

Table 1. Almond butter (plain without added salt) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg1.64
Energykcal614
EnergykJ2568
Proteing20.96
Total lipid (fat)g55.5
Ashg3.09
Carbohydrate, by differenceg18.82
Fiber, total dietaryg10.3
Sugars, totalg4.43
Sucroseg4.34
Glucose (dextrose)g0.02
Fructoseg0
Lactoseg0
Maltoseg0.07
Starchg0.08
Minerals
Calcium, Camg347
Iron, Femg3.49
Magnesium, Mgmg279
Phosphorus, Pmg508
Potassium, Kmg748
Sodium, Namg7
Zinc, Znmg3.29
Copper, Cumg0.934
Manganese, Mnmg2.131
Selenium, Seµg2.4
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.041
Riboflavinmg0.939
Niacinmg3.155
Pantothenic acidmg0.318
Vitamin B-6mg0.103
Folate, totalµg53
Folic acidµg0
Folate, foodµg53
Folate, DFEµg53
Choline, totalmg52.1
Vitamin B-12µg0
Vitamin A, RAEµg0
Retinolµg0
Carotene, betaµg1
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU1
Lycopeneµg0
Lutein + zeaxanthinµg1
Vitamin E (alpha-tocopherol)mg24.21
Tocopherol, betamg0.53
Tocopherol, gammamg1.01
Tocopherol, deltamg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg0
Lipids
Fatty acids, total saturatedg4.152
8:0g0
10:0g0
12:0g0
14:0g0.007
15:0g0
16:0g3.192
17:0g0.007
18:0g0.938
20:0g0.007
22:0g0
Fatty acids, total monounsaturatedg32.445
14:1g0
15:1g0
16:1 undifferentiatedg0.248
17:1g0.035
18:1 undifferentiatedg32.143
20:1g0.019
Fatty acids, total polyunsaturatedg13.613
18:2 undifferentiatedg13.605
18:3 undifferentiatedg0.007
20:2 n-6 c,cg0
20:3 undifferentiatedg0
20:4 undifferentiatedg0
Cholesterolmg0
Phytosterolsmg139
Stigmasterolmg3
Campesterolmg6
Beta-sitosterolmg131
Amino Acids
Tryptophang0.159
Threonineg0.555
Isoleucineg0.813
Leucineg1.483
Lysineg0.612
Methionineg0.122
Cystineg0.242
Phenylalanineg1.149
Tyrosineg0.595
Valineg0.937
Arginineg2.382
Histidineg0.55
Alanineg0.99
Aspartic acidg2.397
Glutamic acidg5.912
Glycineg1.472
Prolineg0.915
Serineg0.926
Other
Alcohol, ethylg0
[Source: United States Department of Agriculture Agricultural Research Service 10 ]

Table 2. Organic almond butter (raw) nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal562
Proteing21.88
Total lipid (fat)g50
Carbohydrate, by differenceg18.75
Fiber, total dietaryg12.5
Sugars, totalg6.25
Minerals
Calcium, Camg250
Iron, Femg4.5
Sodium, Namg0
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU0
Lipids
Fatty acids, total saturatedg3.12
Fatty acids, total transg0
Cholesterolmg0
[Source: United States Department of Agriculture Agricultural Research Service 10 ]

Table 3. Organic almond butter (raw and crunchy) nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal562
Proteing21.88
Total lipid (fat)g50
Carbohydrate, by differenceg18.75
Fiber, total dietaryg12.5
Sugars, totalg6.25
Minerals
Calcium, Camg250
Iron, Femg4.5
Sodium, Namg0
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU0
Lipids
Fatty acids, total saturatedg3.12
Fatty acids, total transg0
Cholesterolmg0
[Source: United States Department of Agriculture Agricultural Research Service 10 ]

Table 4. Organic almond butter (dry roasted unblanched) nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal633
Proteing16.67
Total lipid (fat)g60
Carbohydrate, by differenceg20
Fiber, total dietaryg3.3
Sugars, totalg6.67
Minerals
Calcium, Camg267
Iron, Femg3.6
Potassium, Kmg767
Sodium, Namg0
Vitamins
Vitamin C, total ascorbic acidmg0
Folate, totalµg53
Vitamin A, IUIU0
Lipids
Fatty acids, total saturatedg5
Fatty acids, total monounsaturatedg33.33
Fatty acids, total polyunsaturatedg13.33
Fatty acids, total transg0
Cholesterolmg0
[Source: United States Department of Agriculture Agricultural Research Service 10]

Table 5. Butter (plain without added salt) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg16.17
Energykcal717
EnergykJ2999
Proteing0.85
Total lipid (fat)g81.11
Ashg0.09
Carbohydrate, by differenceg0.06
Fiber, total dietaryg0
Sugars, totalg0.06
Minerals
Calcium, Camg24
Iron, Femg0.02
Magnesium, Mgmg2
Phosphorus, Pmg24
Potassium, Kmg24
Sodium, Namg11
Zinc, Znmg0.09
Copper, Cumg0.016
Manganese, Mnmg0.004
Selenium, Seµg1
Fluoride, Fµg2.8
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.005
Riboflavinmg0.034
Niacinmg0.042
Pantothenic acidmg0.11
Vitamin B-6mg0.003
Folate, totalµg3
Folic acidµg0
Folate, foodµg3
Folate, DFEµg3
Choline, totalmg18.8
Vitamin B-12µg0.17
Vitamin B-12, addedµg0
Vitamin A, RAEµg684
Retinolµg671
Carotene, betaµg158
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU2499
Lycopeneµg0
Lutein + zeaxanthinµg0
Vitamin E (alpha-tocopherol)mg2.32
Vitamin E, addedmg0
Tocopherol, betamg0
Tocopherol, gammamg0
Tocopherol, deltamg0
Vitamin D (D2 + D3)µg0
Vitamin D2 (ergocalciferol)µg0
Vitamin D3 (cholecalciferol)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg7
Lipids
Fatty acids, total saturatedg50.489
4:0g3.226
6:0g2.007
8:0g1.19
10:0g2.529
12:0g2.587
14:0g7.436
16:0g21.697
17:0g0.56
18:0g9.999
20:0g0.138
Fatty acids, total monounsaturatedg23.43
16:1 undifferentiatedg1.82
16:1 cg0.961
18:1 undifferentiatedg20.4
18:1 cg16.978
18:1 tg2.982
20:1g0.1
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg3.01
18:2 undifferentiatedg1.83
18:2 n-6 c,cg2.166
18:2 CLAsg0.267
18:2 ig0.296
18:3 undifferentiatedg1.18
18:3 n-3 c,c,c (ALA)g0.315
18:4g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Cholesterolmg215
Stigmasterolmg0
Campesterolmg0
Beta-sitosterolmg4
Amino Acids
Tryptophang0.012
Threonineg0.038
Isoleucineg0.051
Leucineg0.083
Lysineg0.067
Methionineg0.021
Cystineg0.008
Phenylalanineg0.041
Tyrosineg0.041
Valineg0.057
Arginineg0.031
Histidineg0.023
Alanineg0.029
Aspartic acidg0.064
Glutamic acidg0.178
Glycineg0.018
Prolineg0.082
Serineg0.046
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
[Source: United States Department of Agriculture Agricultural Research Service 10 ]

Table 6. Nutritional property of nut and seed butter (1 Tbsp)

ProductCalorieProteinFatCalciumZinc
(g)(g)(mg)(mg)
Almond butter1012.49.5430.5
Cashew butter932.88.070.8
Hazelnut butter942.09.5
Sunflower butter803.07.0
Sesame butter892.68.0640.7
Peanut butter
 natural943.88.070.4
 reduced fat954.06.00.4
Soy butter
 sweetened854.05.550
 unsweetened804.06.530
Soy-peanut butter502.01.240
 sweetened

Footnote: 1 Tablespoon (Tbsp) = 14.19 g

[Source 11 ]

Almond butter vs peanut butter

Almond butter has significantly more fiber, calcium, and potassium than sunflower seed or peanut butter 12. Spiller et al. 13 compared the lipid-altering effect of roasted salted almonds and roasted almond butter with that of raw almonds, as part of a plant-based diet (Table 10). High-density lipoprotein “good” cholesterol (HDL) did not significantly change with raw or roasted almonds but slightly increased with almond butter. HDL cholesterol is the good cholesterol that cruises the bloodstream and high levels HDL reduces the risk for heart disease.

The findings of this study 14found that consumption of nuts and peanut butter was inversely associated with risk of type 2 diabetes, independent of known risk factors for type 2 diabetes, including age, obesity, family history of diabetes, physical activity, smoking, and dietary factors. Peanut butter (Arachis hypogaea) is creamy, composed of peanut paste and stabilizer. It may also contain sweetener, salt, emulsifier and other ingredients. Peanut butter is prepared by roasting, blanching, grinding and tempering. The formulation of a typical peanut butter is shown in Table 7. Good quality nuts and seed pods are sorted out and destoned before shelling. Shelled nuts are graded to ensure the sound or bold or even size nuts. Roasting is a dry heat treatment, carried out not so much for dehydration but for flavor, color and texture development 15. Roasting involves a number of physico-chemical changes including dehydration and chemical reactions. However, the development of flavor and aroma depends upon the temperature and time of roasting beside the type of nuts and techniques applied 16. Generally, for peanut butter, roasting is done at around 160 °C for 40–60 min depending upon the seed size and moisture contents 17. Roasting reduces water contents to around 1 % followed by the release of oil from the cytoplasm of the cells which increases the shelf life of peanuts and helps in developing flavor for peanut butter. Ogunsanwo et al. 18 reported that the peanut butter prepared by roasting at 160 °C for 30 min was found comparable with the commercial samples. Blanching of peanuts is done to remove the skin of the peanut. There are several blanching methods including dry, water, spin, and air impact. Dry blanching is used primarily in peanut butter production, as it removes the kernel hearts which affect peanut butter flavor. After removing the outer skin during blanching, nuts are ground into paste. Peanut butter is usually made by two stage grinding operations. First grinding reduces the nuts to a medium size and the second milling uses a very high-speed grinder cum mixer that has a combination of cutting-shearing and attrition action and reduces to a fine (less than 0.025 cm) smooth texture. Due to this several passes the paste is subjected to excessively high temperature, an elaborative cooling methods need to be utilized to retain desired flavors in the nut butter. Connick 19 states that accomplishing the grinding steps in the presence of solid carbon dioxide inhibits the dissolving, occlusion, and adsorption of free oxygen into the peanut butter and there by increases the shelf life as well as improves the flavor. Woodroof 20 classified peanut butters into three types based on the texture viz., Smooth (even texture with no perceptible grainy peanut particles), Regular (definitely grainy texture with with perceptible peanut particles not more than 1/16 in. in diameter and Chunky (partially fine and partially grainy particles with substantial amounts larger than 1/16 in. in diameter). Crippen et al. 21 reported that increased grind size (fine, medium and course), decreased the sensory smoothness, spreadability, adhesiveness and preference ratings. According to Dzurik et al. 22 the high pressure homogenization after initial grinding produces a paste of smooth, glossy, melts more rapidly in the mouth than conventional peanut butter. During grinding, the ingredients like salt, sugar, stabilizers and emulsifiers are added. Addition of salt (< 1.2 %) increased the ease of swallowing, as well as consumer preference of texture. Before grinding of nut/seeds, carbohydrates, protein and other non-fat components will be in a continuous phase. Fat cells entrapped in non-fat components will be in a discontinuous phase. After grinding into paste, fat cells ruptured and become continuous and non-fat constituents form a discontinuous phase. Once the paste is formed, continuous phase (fat/ oil) will separate from the nonfat particles. Without stabilizers, paste settles at the bottom and forms a hard layer while the oil remains on top 23. Thus, stabilizers in plant based butter prevent gravitational separation of less dense oil from solid particles during storage at ambient temperatures 24. Galvez et al. 25 reported that the peanut butter without stabilizer exhibited > 2 % oil separation after 12 weeks of storage. During conditioning to prevent oil separation, mixture is immediately chilled and the hydrogenated oil forms finely divided and sufficient amount of hard fat crystals. The amount and nature of the crystals determines the stability of the product. The rate of cooling determines the size of the crystals 26. Woodroof 27 has discussed the important considerations on type and amount of stabilizer with respect to the desired consistency and mouth feel of peanut butter, oil content and particle size. The temperature of paste during the addition of stabilizer should be more than the melting point of stabilizer to produce a more homogenized product. Thus, the recommended temperature for blending of stabilizers is 60–74 °C. Totlani and Chinnan 28 reported that the addition of 1–2 % stabilizer was found to be adequate for peanut butter stored for 3 months at 35 °C. Aryana et al. 29 and Gills and Resurreccion 30 reported that the use of blended hydrogenated rapeseed and cottonseed oils as stabilizer in peanut butter was superior to palm oil. Addition of emulsifier in the peanut butter negates stickiness so that it will not stick to the roof of the mouth. Suitable emulsifiers include lecithin and fatty mono- and diglycerides, for example, soybean mono- and diglycerides 31. Different emulsifiers affirmed as GRAS are shown in Table 8. Furthermore, for improved stability, the peanut butter should be packed at the proper temperature and it should be tempered for a minimum of 24 h before shipping. This tempering allows time for additional crystal growth and formation of a good crystalline network 26.

Table 7. Formulation of a typical peanut butter

ComponentPercentage
Peanut paste (~1 % moisture)90
Hydrogenated vegetable oil1–5
Sweetener1–6
Salt1–1.5
Emulsifier0.5–1.5
[Source 32 ]

Table 8. Some food emulsifiers affirmed as GRAS

EmulsifierUS FDA (21CFR)EEC (E No.)
Diacetyl tartaric esters of monoglycerides (DATEM)184.1101E472e
Lecithin184.1400E322
Mono-and diglycerides184.1505E471
Monosodium phosphate derivatives of mono and diglycerides184.1521
[Source 33 ]

Table 9. Peanut butter (raw) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg6.5
Energykcal567
EnergykJ2374
Proteing25.8
Total lipid (fat)g49.24
Ashg2.33
Carbohydrate, by differenceg16.13
Fiber, total dietaryg8.5
Sugars, totalg4.72
Minerals
Calcium, Camg92
Iron, Femg4.58
Magnesium, Mgmg168
Phosphorus, Pmg376
Potassium, Kmg705
Sodium, Namg18
Zinc, Znmg3.27
Copper, Cumg1.144
Manganese, Mnmg1.934
Selenium, Seµg7.2
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.64
Riboflavinmg0.135
Niacinmg12.066
Pantothenic acidmg1.767
Vitamin B-6mg0.348
Folate, totalµg240
Folic acidµg0
Folate, foodµg240
Folate, DFEµg240
Choline, totalmg52.5
Betainemg0.6
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg0
Retinolµg0
Carotene, betaµg0
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU0
Lycopeneµg0
Lutein + zeaxanthinµg0
Vitamin E (alpha-tocopherol)mg8.33
Vitamin E, addedmg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg0
Lipids
Fatty acids, total saturatedg6.279
04:00:00g0
06:00:00g0
08:00:00g0
10:00:00g0
12:00:00g0
14:00:00g0.025
16:00:00g5.154
18:00:00g1.1
Fatty acids, total monounsaturatedg24.426
16:1 undifferentiatedg0.009
18:1 undifferentiatedg23.756
20:01:00g0.661
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg15.558
18:2 undifferentiatedg15.555
18:3 undifferentiatedg0.003
18:04:00g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Fatty acids, total transg0
Cholesterolmg0
Amino Acids
Tryptophang0.25
Threonineg0.883
Isoleucineg0.907
Leucineg1.672
Lysineg0.926
Methionineg0.317
Cystineg0.331
Phenylalanineg1.377
Tyrosineg1.049
Valineg1.082
Arginineg3.085
Histidineg0.652
Alanineg1.025
Aspartic acidg3.146
Glutamic acidg5.39
Glycineg1.554
Prolineg1.138
Serineg1.271
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
Isoflavones
Daidzeinmg0.02
Genisteinmg0.24
Total isoflavonesmg0.26
Biochanin Amg0.01
Formononetinmg0
Coumestrolmg0
Proanthocyanidin
Proanthocyanidin dimersmg33.2
Proanthocyanidin trimersmg48.8
Proanthocyanidin 4-6mersmg48.1
Proanthocyanidin 7-10mersmg0
Proanthocyanidin polymers (>10mers)mg0
[Source: United States Department of Agriculture Agricultural Research Service 10]

Is almond butter good for you?

The answer to that question is yes. Almond consumption has been shown to reduce LDL “bad” cholesterol (LDL-C) concentrations and increase HDL “good” cholesterol (HDL-C) concentrations in hyperlipidaemic individuals 34. Although almonds contain a variety of constituents that may exert cardioprotective effects through various mechanisms 35, their ability to improve blood lipid profiles and reduce coronary heart disease risk may primarily be related to their healthy fatty acid profile, which is low in saturated fats and high in monounsaturated fats (MUFA) 36, particularly oleic acid 37. Epidemiological studies suggest that diets with a high proportion of monounsaturated fatty acid (MUFA) in the form of oleic acid, such as the Mediterranean diet, reduce coronary heart disease risk 38. However, the effect of almond consumption on the serum fatty acid profile and its association with coronary heart disease risk have not been investigated.

Almond butter benefits

The results of this study 39 indicate that almond consumption favourably alters the serum fatty acid profile by increasing the proportions of oleic acid and total monounsaturated fatty acid (MUFA) and decreasing those of saturated fatty acid. These changes in the fatty acid profile are correlated with improvements in blood lipoproteins and with a decreased 10-year coronary heart disease risk. The mechanism by which almonds modify coronary heart disease risk is unclear, it has been proposed that almonds may exert an effect exogenously and endogenously. It has been proposed that dietary incorporation of almonds exogenously reduces serum cholesterol concentrations by replacing saturated fats with monounsaturated fats in the diet. In a randomized, controlled, parallel study, the saturated fats concentrations of thirty-eight hypercholesterolemic adults who consumed 100 g of raw almonds daily over a 4-week period were found to be lower 40. Furthermore, increasing monounsaturated fatty acid (MUFA) intake has been reported to be associated with an increase in HDL “good” cholesterol concentrations, as demonstrated by a randomized, controlled trial of twenty-four hypercholesterolaemic adults 41. The improvement in blood lipid profiles has generally been associated with a reduced risk of coronary heart disease. It has also been proposed that almonds may act endogenously to exert a cardioprotective effect. Dietary fatty acid are rapidly incorporated into lipoprotein lipids. Enrichment of lipoprotein particles with monounsaturated fatty acid (MUFA) at the expense of polyunsaturated fatty acid (PUFA) may enhance their resistance to oxidative stress as there are few double bonds to react with, thus potentiating the anti-atherogenic effect 42. Moreover, there may be other bioactive components in almonds that further reduce coronary heart disease risk. In addition to unsaturated fatty acids, almonds are a good source of vitamin E, fiber and phytochemicals (phenols, flavonoids, proanthocyanidins and phytosterols), arginine, Cu and Mg, which may beneficially influence coronary artery disease risk 43. Many of these nutrients may act synergistically to produce the observed favourable outcomes, although further studies are required to prove this postulation 44. Further analysis of LDL particle size may provide a better understanding of potential mechanisms by which almonds and other foods rich in monounsaturated fatty acid (MUFA) influence triglyceride concentrations.

Almonds have potential health benefits and reduce risk factors associated with type 2 diabetes, cardiovascular disease, cancer and obesity 45. Previous studies have established that almond cell walls play a crucial role in regulating nutrient bioaccessibility in the gastrointestinal tract (GIT) 46. The term ‘bioaccessibility’ is defined as the proportion of a nutrient or phytochemical compound ‘released’ from a complex food matrix during digestion and, therefore, potentially available for absorption in the gastrointestinal tract (GIT). Using a in test tube and an animal study, scientists have recently demonstrated that test meals containing almonds of different particle sizes behaved differently: the degree of lipid encapsulation affected the rate and extent of bioaccessibility in the upper GIT 47. Scientists have also demonstrated that mastication of natural raw almonds released only a small proportion (7.9%) of the total lipid and was only slightly higher for roasted almonds (11.1%) 48. The lipid release from masticated almonds was in close agreement with that predicted by a theoretical model for almond lipid bioaccessibility 49. Using a test tube model of duodenal digestion 50, it was observed that a decrease in almond particle size resulted in an increased rate and extent of lipolysis.

Novotny et al. 51 conducted a feeding study in healthy adults to determine the energy value of almonds as a representative food from a group for which the Atwater factors may overestimate the energy value. They showed that only 76% of the energy contained within almonds (based on the Atwater factors) was actually metabolised 51. Furthermore, when calculating the metabolisable energy  of whole natural almonds, whole roasted almonds, chopped almonds and almond butter, it was demonstrated that the number of calories absorbed was dependent on the form in which almonds were consumed.

It is known that processing of nuts, such as roasting, chopping and grinding, impacts mastication, particle size and lipid bioaccessibility 48. The decrease in size of almond particles, with consequent reduction of intact cell walls, determines the rate and extent of lipid bioaccessibility during digestion. It is interesting to note that there was limited lipid digestibility for natural raw almonds and roasted almonds during mastication. In almond butter from roasted almonds, all the intracellular lipids made available by cell-wall rupture, as well as the lipid molecules present at the interface and within the continuous lipid phase are readily available for absorption. The exposure of the remaining intact almond particles to mastication resulted in a further small release of lipid. Cassady et al. 52 reported important differences in appetitive and hormone responses after mastication of almonds. Gebauer et al. 53 have recently reported that the number of calories absorbed from almonds in the gastrointestinal tract is strictly dependent on the form in which they are consumed. As a result of incomplete macronutrient loss in the upper gastrointestinal tract, it is believed that a large proportion of nutrients from almonds reaches the large bowel, where it is fermented by the microbiota 46. Incomplete rupturing of the cell walls during mastication results in macronutrient encapsulation, which remain inaccessible to digestive enzymes and, if not fermented in the colon, are excreted in feces.

Table 10. Composition of raw and processed almonds per 100g edible portion

Raw AlmondsRoasted AlmondsAlmond Butter
Water (g)4.21.32.1
Protein (g)25.325.424.6
Total lipid (g)49.552.555.7
MUFA (g)30.732.132.7
PUFA (g)10.611.413.8
SFA (g)3.53.73.9
Carbohydrate (g)17.918.514.5
Dietary fiber (g)13.911.810.5
Vitamin E (mg ATE)25.325.523.6
Phytosterols (mg)113.6125.8145.1
Sodium (mg)<10209<10
[Source 13 ]

Unsaturated fats

Unsaturated fats, which are liquid at room temperature, are considered beneficial fats because they can improve blood cholesterol levels, ease inflammation, stabilize heart rhythms, and play a number of other beneficial roles. Unsaturated fats are predominantly found in foods from plants, such as vegetable oils, nuts, and seeds.

There are two types of “good” unsaturated fats:

1. Monounsaturated fats are found in high concentrations in:

  • Nuts such as almonds, hazelnuts, and pecans
  • Seeds such as pumpkin and sesame seeds
  • Olive, peanut, and canola oils
  • Avocados

2. Polyunsaturated fats are found in high concentrations in:

  • Sunflower, corn, soybean, and flaxseed oils
  • Walnuts
  • Flax seeds
  • Fish
  • Canola oil – though higher in monounsaturated fat, it’s also a good source of polyunsaturated fat.

Omega-3 fats are an important type of polyunsaturated fat. The body can’t make these, so they must come from food.

An excellent way to get omega-3 fats is by eating fish 2-3 times a week.

Good plant sources of omega-3 fats include flax seeds, walnuts, and canola or soybean oil.

Higher blood omega-3 fats are associated with lower risk of premature death among older adults, according to a study 54.

Most people don’t eat enough healthful unsaturated fats. The American Heart Association suggests that 8-10 percent of daily calories should come from polyunsaturated fats, and there is evidence that eating more polyunsaturated fat—up to 15 percent of daily calories—in place of saturated fat can lower heart disease risk 54.

Dutch researchers conducted an analysis of 60 trials that examined the effects of carbohydrates and various fats on blood lipid levels. In trials in which polyunsaturated and monounsaturated fats were eaten in place of carbohydrates, these good fats decreased levels of harmful LDL and increased protective HDL 55.

More recently, a randomized trial known as the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart) showed that replacing a carbohydrate-rich diet with one rich in unsaturated fat, predominantly monounsaturated fats, lowers blood pressure, improves lipid levels, and reduces the estimated cardiovascular risk 56.

foods with healthy fats

Saturated Fats

All foods containing fat have a mix of specific types of fats. Even healthy foods like chicken and nuts have small amounts of saturated fat, though much less than the amounts found in butter, ghee, coconut oil, beef, cheese and ice cream. Saturated fat is mainly found in animal foods, but a few plant foods are also high in saturated fats, such as coconut, coconut oil, palm oil, and palm kernel oil.

  • The Dietary Guidelines for Americans recommends getting less than 10 percent of calories each day from saturated fat 57.
  • The American Heart Association goes even further, recommending limiting saturated fat to no more than 7 percent of calories 58.
  • Cutting back on saturated fat will likely have no benefit, however, if people replace saturated fat with refined carbohydrates. Eating refined carbohydrates in place of saturated fat does lower “bad” LDL cholesterol, but it also lowers the “good” HDL cholesterol and increases triglycerides. The net effect is as bad for the heart as eating too much saturated fat.

In the United States, the biggest sources of saturated fat 59 in the diet are:

  • Pizza and cheese
  • Whole and reduced fat milk, butter and dairy desserts
  • Meat products (sausage, bacon, beef, hamburgers)
  • Cookies and other grain-based desserts
  • A variety of mixed fast food dishes

Though decades of dietary advice 60 suggested saturated fat was harmful, in recent years that idea has begun to evolve. Several studies suggest that eating diets high in saturated fat do not raise the risk of heart disease, with one report analyzing the findings of 21 studies that followed 350,000 people for up to 23 years.

Investigators looked at the relationship between saturated fat intake and coronary heart disease (coronary artery disease), stroke, and cardiovascular disease. Their controversial conclusion: “There is insufficient evidence from prospective epidemiologic studies to conclude that dietary saturated fat is associated with an increased risk of coronary heart disease, stroke, or cardiovascular disease” 60.

A well-publicized 2014 study questioned the link between saturated fat and heart disease, but nutrition experts determined the paper to be seriously misleading. In order to set the record straight, Harvard School of Public Health convened a panel of nutrition experts and held a teach-in, “Saturated or not: Does type of fat matter?“

The overarching message is that cutting back on saturated fat can be good for health if people replace saturated fat with good fats, especially, polyunsaturated fats 61, 62. Eating good fats in place of saturated fat lowers the “bad” LDL cholesterol, and it improves the ratio of total cholesterol to “good” HDL cholesterol, lowering the risk of heart disease.

Eating good fats in place of saturated fat can also help prevent insulin resistance, a precursor to diabetes 63. So while saturated fat may not be as harmful as once thought, evidence clearly shows that unsaturated fat remains the healthiest type of fat.

Trans Fats

Trans fatty acids, more commonly called trans fats, are made by heating liquid vegetable oils in the presence of hydrogen gas and a catalyst, a process called hydrogenation.

Partially hydrogenating vegetable oils makes them more stable and less likely to become rancid. This process also converts the oil into a solid, which makes them function as margarine or shortening.

Partially hydrogenated oils can withstand repeated heating without breaking down, making them ideal for frying fast foods.

For these reasons, partially hydrogenated oils became a mainstay in restaurants and the food industry – for frying, baked goods, and processed snack foods and margarine.

Partially hydrogenated oil is not the only source of trans fats in our diets. Trans fats are also naturally found in beef fat and dairy fat in small amounts.

Eliminating industrial-produced trans fats from the U.S. food supply could prevent between 6 and 19 percent of heart attacks and related deaths, or as much as 200,000 each year 64.

Trans fats are worse for cholesterol levels than saturated fats because they:

  • Raise bad LDL “bad” cholesterol and lower good HDL “good” cholesterol
  • Create inflammation 65 – a reaction related to immunity – which has been implicated in heart disease, stroke, diabetes, and other chronic conditions
  • Contribute to insulin resistance 66
  • Can have harmful health effects even in small amounts – for each additional 2 percent of calories from trans fat consumed daily, the risk of coronary heart disease increases by 23 percent.

Eliminating trans fats from food

In the 1990s, the average American was eating about 6 grams of trans fats a day; ideally that should be under 1 gram a day, and zero from partially hydrogenated oils is best 67.

A 2006 labeling law required food companies to list trans fats on food labels. This caused many food makers to switch to using trans-fat-free oils and fats in their products, resulting in a reduction of trans fat levels in the U.S. food supply.

A study from the Centers for Disease Control and Prevention 68 found that Americans’ blood-levels of trans fats dropped 58 percent from 2000 to 2009—evidence that the labeling law has had its desired effect.

A survey of 83 major-brand grocery store products and restaurant dishes offers encouraging news: When most of these food makers reformulated their products, they cut back on trans fat without increasing saturated fat 69.

If a product contains less than half a gram of trans fat and a half gram of saturated fat per serving, it can still be labeled as “trans fat-free.” So while many products in the United States are labeled “trans fat-free,” those products may still contain a small amount of trans fat.

In June 2015 the FDA announced its decision to ban artificial trans fat in the food supply. Food manufacturers in the U.S. will have three years to remove partially hydrogenated oils — the primary source of artificial trans fat — from products.

While we’re making progress in the United States, trans-fat intake is widely used in some developing nations. Inexpensive partially hydrogenated soybean oil and palm oil have become staples not only for the food industry but also for home use. This shift away from traditional cooking oils and toward trans-rich partially hydrogenated oils is contributing to the growing epidemic of cardiovascular disease in developing nations around the world.

  1. Mangels R (2001). Guide to nut and nut butters. Vegetarian J XXI:20–23[]
  2. Jiang R, Manson JE, Stampfer MJ, Liu S, Willett WC, Hu FB. Nut and peanut butter consumption and risk of type 2 diabetes in women. J Am Med Assoc. 2002;288:2554–2560. doi: 10.1001/jama.288.20.2554 https://jamanetwork.com/journals/jama/fullarticle/195554[]
  3. Wilkes RS (2012) Nut butter and related products enriched with omega-3. US patent. Publication number: US 2012/0164307 A1[]
  4. https://www.uoguelph.ca/foodscience/[]
  5. Fat content of dairy products, eggs, margarines and oils: implications for atherosclerosis. Scherr C, Ribeiro JP. Arq Bras Cardiol. 2010 Jul; 95(1):55-60. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2010005000074[]
  6. Paleolithic nutrition. A consideration of its nature and current implications. Eaton SB, Konner M. N Engl J Med. 1985 Jan 31; 312(5):283-9. https://www.nejm.org/doi/full/10.1056/NEJM198501313120505[]
  7. Jenkins DJA, Hu FB, Tapsell LC, Josse AR, Kendall CWC. Possible benefit of nuts in type 2 diabetes. J Nutr. 2008;138(9):1752S–1756S. https://www.ncbi.nlm.nih.gov/pubmed/18716181[]
  8. Almond. Wikipedia. https://en.wikipedia.org/wiki/Almond[]
  9. Stern, Kingsley R. (1997). Introductory Plant Biology (Seventh ed.). Dubuque: Wm. C. Brown. ISBN 0-07-114448-X.[]
  10. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][][][][][]
  11. Gorrepati K, Balasubramanian S, Chandra P. Plant based butters. Journal of Food Science and Technology. 2015;52(7):3965-3976. doi:10.1007/s13197-014-1572-7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486598/[]
  12. Thomas R and Gebhardt S (2010) Sunflower and almond butter as nutrient-rich alternatives to peanut butter. American dietetic association, Food & Nutrition Conference & Expo. Boston, MA.[]
  13. Spiller GA, Miller A, Olivera K, Reynolds J, Miller B, Morse SJ, Dewell A, Farquhar JW. Effects of plant-based diets high in raw or roasted almonds, or roasted almond butter on serum lipoproteins in humans. J Am Coll Nutr. 2003;22(3):195–200. doi: 10.1080/07315724.2003.10719293 https://www.ncbi.nlm.nih.gov/pubmed/12805245[][]
  14. Nut and Peanut Butter Consumption and Risk of Type 2 Diabetes in Women. JAMA. 2002;288(20):2554-2560. doi:10.1001/jama.288.20.2554 https://jamanetwork.com/journals/jama/fullarticle/195554[]
  15. Alamprese C, Ratti S, Rossi M. Effects of roasting conditions on hazelnut characteristics in a two-step process. J Food Eng. 2009;95(2):272–279. doi: 10.1016/j.jfoodeng.2009.05.001[]
  16. Shakerardekani A, Karim R, Ghazali HM, Chin NL. Effect of roasting conditions on hardness, moisture content and colour of pistachio kernels. Food Res Int. 2011;18:723–729[]
  17. Pattee HE, Pearson JL, Young CT, Giesbrecht FG. Changes in roasted peanut flavor and other quality factors with seed size and storage time. J Food Sci. 1982;47(2):455–456. doi: 10.1111/j.1365-2621.1982.tb10102.x[]
  18. Ogunsanwo BM, Faboya OOP, Idowu OR, Adewuyi GO. Short communication, using rating to evaluate quality of peanut products. Afr J Biotechnol. 2005;4(12):1469–1471[]
  19. Connick FC (1997) Peanut butter manufacture. US Patent. Patent number: US 4,004,037A.[]
  20. Woodroof JG. Chapter 9, peanut butter. In: Woodroof JG, editor. Peanuts: Production, Processg, Products. 3. Westport: AVI Publishing Co., Inc.; 1983. pp. 181–227[]
  21. Crippen KL, Hamann DD, Young CT. Effects of grind size, sucrose concentration and salt concentration on peanut butter texture. J Texture Stud. 1989;20(1):29–41. doi: 10.1111/j.1745-4603.1989.tb00418.x[]
  22. Dzurik J W, Hair ER, Hardy ME, Purves ER (1971) Peanut butter containing homogenized peanut paste. US patent. Publication number: US 3 619 207A[]
  23. Aryana KJ, Resurreccion AVA, Chinnan MS, Beuchat LR. Microstructure of peanut butter stabilized with palm oil. J Food Process Preserv. 2000;24:229–241. doi: 10.1111/j.1745-4549.2000.tb00415.x[]
  24. Hinds MJ, Chinnan MS and Beuchat LR (1994) Unhydrogenated palm oil as a stabilizer for peanut butter. J Food Sci 59: 816–820 & 832[]
  25. Galvez FCF, Francisco ML, Lustre AO and Resurreccion AVA (2006) Chapter 1, Quality improvement for local unstabilized peanut butter. In: Lustre AO, Francisco ML, Palomar LS & Resurreccion AVA (Eds), Monograph series No.6: Peanut butter and spreads, USA, Philippines, pp 20–47[]
  26. Francisco ML, Galvez FCF, Lustre AO and Resurreccion AVA (2006) Chapter 2, Screening of local stabilizers for Philippine peanut butter. In: Lustre AO, Francisco ML, Palomar LS & Resurreccion AVA (Eds), Monograph series No.6: Peanut butter and spreads, USA, Philippines, pp 48–64[][]
  27. Woodroof JG. Chapter 9, peanut butter. In: Woodroof JG, editor. Peanuts: Production, Processg, Products. 3. Westport: AVI Publishing Co., Inc.; 1983. pp. 181–227.[]
  28. Totlani VM, Chinnan MS. Effect of stabilizer levels and storage conditions on texture and viscosity of peanut butter. Peanut Sci. 2007;34(1):1–9. doi: 10.3146/0095-3679(2007)34[1:EOSLAS]2.0.CO;2[]
  29. Aryana KJ, Resurreccion AVA, Chinnan MS, Beuchat LR. Functionality of palm oil as a stabilizer in peanut butter. J Food Sci. 2003;68:1301–1307. doi: 10.1111/j.1365-2621.2003.tb09643.x[]
  30. Gills LA, Resurreccion AVA. Sensory and physical properties of peanut butter treated with palm oil and hydrogenated vegetable oil to prevent oil separation. J Food Sci. 2000;65:173–180. doi: 10.1111/j.1365-2621.2000.tb15975.x[]
  31. Hunter JE and Eck JR (1989) Reduced calorie peanut butter. US patent. Publication number: US 4863753 A[]
  32. Akhtar S, Khalid N, Ahmed I, Shahzad A, Suleria HAR. Physicochemical charecteristics, functional properties, and nutritional benefits of peanut oil: a review. Crit Rev Food Sci Nutr. 2014;54(12):1562–1575. doi: 10.1080/10408398.2011.644353. https://www.ncbi.nlm.nih.gov/pubmed/24580558[]
  33. Hasenhuett GL. Overview of food emulsifiers. In: Hasenhuettl GL, Hartel RW, editors. Food emulsifiers and their applications. 2. New York: Springer; 2008. pp. 1–9.[]
  34. Jenkins DJ, Kendall CW, Marchie A, et al. (2002) Dose response of almonds on coronary heart disease risk factors: blood lipids, oxidized low-density lipoproteins, lipoprotein(a), homocysteine, and pulmonary nitric oxide: a randomized, controlled, crossover trial. Circulation 106, 1327–1332 http://circ.ahajournals.org/content/106/11/1327.long[]
  35. Kris-Etherton PM, Hu FB, Ros E, et al. (2008) The role of tree nuts and peanuts in the prevention of coronary heart disease: multiple potential mechanisms. J Nutr 138, 1746S–1751S https://www.ncbi.nlm.nih.gov/pubmed/18716180[]
  36. Robbins KS, Shin EC, Shewfelt RL, et al. (2011) Update on the healthful lipid constituents of commercially important tree nuts. J Agric Food Chem 59, 12083–12092 https://www.ncbi.nlm.nih.gov/pubmed/21985331[]
  37. Sathe SK, Seeram NP, Kshirsagar HH, et al. (2008) Fatty acid composition of California grown almonds. J Food Sci 73, C607–C614 https://www.ncbi.nlm.nih.gov/pubmed/19021789[]
  38. Sanders TA (2001) Olive oil and the Mediterranean diet. Int J Vitam Nutr Res 71, 179–184 https://www.ncbi.nlm.nih.gov/pubmed/11582840[]
  39. Nishi S, Kendall CWC, Gascoyne A-M, et al. Effect of almond consumption on the serum fatty acid profile: a dose–response study. The British Journal of Nutrition. 2014;112(7):1137-1146. doi:10.1017/S0007114514001640. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189119/[]
  40. Spiller GA, Miller A, Olivera K, et al. (2003) Effects of plant-based diets high in raw or roasted almonds, or roasted almond butter on serum lipoproteins in humans. J Am Coll Nutr 22, 195–200 https://www.ncbi.nlm.nih.gov/pubmed/12805245[]
  41. Jenkins DJA, Chiavaroli L, Wong JMW, et al. (2010) Adding monounsaturated fatty acids to a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia. CMAJ 182, 1961–1967 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001502/[]
  42. Ros E & Mataix J (2006) Fatty acid composition of nuts – implications for cardiovascular health. Br J Nutr 96, Suppl. 2, S29–S35 https://www.ncbi.nlm.nih.gov/pubmed/17125530[]
  43. Bolling BW, Dolnikowski G, Blumberg JB, et al. (2010) Polyphenol content and antioxidant activity of California almonds depend on cultivar and harvest year. Food Chem 122, 819–825 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276397/[]
  44. Kris-Etherton PM, Zhao G, Binkoski AE, et al. (2001) The effects of nuts on coronary heart disease risk. Nutr Rev 59, 103–111 https://www.ncbi.nlm.nih.gov/pubmed/11368503[]
  45. Del Gobbo L.C., Falk M.C., Feldman R., Lewis K., Mozaffarian D. Effects of tree nuts on blood lipids, apolipoproteins, and blood pressure: Systematic review, meta-analysis, and dose-response of 61 controlled intervention trials. Am. J. Clin. Nutr. 2015;102:1347–1356. doi: 10.3945/ajcn.115.110965 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658458/[]
  46. Mandalari G., Faulks R.M., Rich G.T., Lo Turco V., Picout D.R., Lo Curto R.B., Bisignano G., Dugo P., Dugo G., Waldron K.W., et al. Release of protein, lipid, and vitamin E from almond seeds during digestion. J. Agric. Food Chem. 2008;56:3409–3416. doi: 10.1021/jf073393v https://www.ncbi.nlm.nih.gov/pubmed/18416553[][]
  47. Grassby T., Mandalari G., Grundy M.M., Edwards C.H., Bisignano C., Trombetta D., Smeriglio A., Chessa S., Ray S., Sanderson J., et al. In vitro and in vivo modeling of lipid bioaccessibility and digestion from almond muffins: The importance of the cell-wall barrier mechanism. J. Funct. Foods. 2017;37:263–271. doi: 10.1016/j.jff.2017.07.046 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628021/[]
  48. Grundy M.M., Grassby T., Mandalari G., Waldron K.W., Butterworth P.J., Berry S.E., Ellis P.R. Effect of mastication on lipid bioaccessibility of almonds in a randomized human study and its implications for digestion kinetics, metabolizable energy, and postprandial lipemia. Am. J. Clin. Nutr. 2015;101:25–33. doi: 10.3945/ajcn.114.088328 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266890/[][]
  49. Grassby T., Picout D.R., Mandalari G., Faulks R.M., Kendall C.W., Rich G.T., Wickham M.S., Lapsley K., Ellis P.R. Modelling of nutrient bioaccessibility in almond seeds based on the fracture properties of their cell walls. Food Funct. 2014;5:3096–3106. doi: 10.1039/C4FO00659C https://www.ncbi.nlm.nih.gov/pubmed/25310222[]
  50. Grundy M.M., Wilde P.J., Butterworth P.J., Gray R., Ellis P.R. Impact of cell wall encapsulation of almonds on in vitro duodenal lipolysis. Food Chem. 2015;185:405–412. doi: 10.1016/j.foodchem.2015.04.013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430076/[]
  51. Novotny J.A., Gebauer S.K., Baer D.J. Discrepancy between the Atwater factor predicted and empirically measured energy values of almonds in human diets. Am. J. Clin. Nutr. 2012;96:296–301. doi: 10.3945/ajcn.112.035782 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396444/[][]
  52. Cassady B.A., Hollis J.H., Fulford A.D., Considine R.V., Mattes R.D. Mastication of almonds: Effects of lipid bioaccessibility, appetite, and hormone response. Am. J. Clin. Nutr. 2009;89:794–800. doi: 10.3945/ajcn.2008.26669 https://www.ncbi.nlm.nih.gov/pubmed/19144727[]
  53. Gebauer S.K., Novotny J.A., Bornhorst G.M., Baer D.J. Food processing and structure impact the metabolizable energy of almonds. Food Funct. 2016;7:4231–4238. doi: 10.1039/C6FO01076H https://www.ncbi.nlm.nih.gov/pubmed/27713968[]
  54. Mozaffarian, D., R. Micha, and S. Wallace, Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med, 2010. 7(3): p. e1000252.[][]
  55. Mensink, R.P., et al., Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr, 2003. 77(5): p. 1146-55.[]
  56. Appel, L.J., et al., Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial. JAMA, 2005. 294(19): p. 2455-64.[]
  57. Dietary Guidelines for Americans. https://health.gov/dietaryguidelines/[]
  58. Lichtenstein, A.H., et al., Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation, 2006. 114(1): p. 82-96.[]
  59. Institute, N.C., Risk Factor Monitoring and Methods: Table 1. Top Food Sources of Saturated Fat among U.S. Population, 2005–2006. NHANES.[]
  60. Siri-Tarino, P.W., et al., Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr, 2010. 91(3): p. 535-46[][]
  61. Astrup, A., et al., The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010? Am J Clin Nutr, 2011. 93(4): p. 684-8.[]
  62. Farvid MS, Ding M, Pan A, Sun Q, Chiuve SE, Steffen LM, Willett WC, Hu FB. Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. Circulation, 2014.[]
  63. Riserus, U., W.C. Willett, and F.B. Hu, Dietary fats and prevention of type 2 diabetes. Prog Lipid Res, 2009. 48(1): p. 44-51.[]
  64. Mozaffarian, D., et al., Trans fatty acids and cardiovascular disease. N Engl J Med, 2006. 354(15): p. 1601-13.[]
  65. Mozaffarian, D., et al., Dietary intake of trans fatty acids and systemic inflammation in women. Am J Clin Nutr, 2004. 79(4): p. 606-12.[]
  66. Riserus, U., W.C. Willett, and F.B. Hu, Dietary fats and prevention of type 2 diabetes. Prog Lipid Res, 2009. 48(1): p. 44-51[]
  67. Allison, D.B., et al., Estimated intakes of trans fatty and other fatty acids in the US population. J Am Diet Assoc, 1999. 99(2): p. 166-74; quiz 175-6.[]
  68. Vesper, H.W., et al., Levels of plasma trans-fatty acids in non-Hispanic white adults in the United States in 2000 and 2009. JAMA, 2012. 307(6): p. 562-3.[]
  69. Mozaffarian, D., M.F. Jacobson, and J.S. Greenstein, Food reformulations to reduce trans fatty acids. N Engl J Med, 2010. 362(21): p. 2037-9.[]
read more

Adzuki beans

adzuki beans

What are adzuki beans

Adzuki bean (Vigna angularis L.), sometimes called small red beans (approximately 5 mm) or English red mung bean, is a dietary legume crop in East Asian countries like China, Japan, and Korea as an ingredient for traditional dessert cuisines due to its sweet taste, as well as its nutritious protein and starch contents 1. Consumption of legumes potentially reduces the risk of chronic diseases 2 such as stroke, type II diabetes 3, cardiovascular 4, and gastrointestinal cancer 5. In addition to fiber, legume grains also contain many substances to improve health such as vitamins, minerals, and other substances, including phenolic compounds 3. The annual cultivation area for adzuki bean in China, Japan, Korean peninsula, and Taiwan is estimated to be 670,000, 120,000, 30,000, and 20,000 hectares, respectively 6. The wild species of adzuki bean such as Vigna angularis var. nipponensis, Vigna nakashimae, and Vigna nepalensis, are widely distributed across East Asia and Himalayan countries 7. However, archaeological evidences suggested multiple domestication origins in northeast Asia 8. The Adzuki bean cultivars most familiar in Northeast Asia have a uniform red color, however, white, black, gray, and variously mottled varieties also are known.

The predominant use of adzuki beans in traditional Japanese confections is a paste or wagashi such as youkan, manju and amanatto 9. Adzuki beans are a rich source of carbohydrates, protein, vitamins, minerals and fiber 10; however, adzuki beans also contain antinutritional factors 11. Antinutritional factors are substances that when present in human foods or water reduce the availability of one or more nutrients. Phytates, α-galactosides and trypsin inhibitors are among these antinutritional factors, and their concentrations differ widely among the different cultivars of adzuki beans. Therefore, when adzuki beans are used for confectionaries, they are boiled in a cooker and yield a hot water extract as a by-product, which is known to contain active ingredients, but is discarded. It has been reported that the 40% (w/v) ethanol fraction of the hot-water extract from adzuki beans suppresses not only proliferation of human stomach cancer cells in culture but also benzo(α)pyrene-induced tumorigenesis in the mouse fore-stomach 12. Thus, the hot-water extract of adzuki beans has a number of effects according to studies in animals (e.g., rats) 13. Thompson et al. 14 have reported that polyphenols and phytic acid have potential hypoglycemic activity. A study in rats with with streptozotocin induced diabetes show that adzuki bean paste produced by boiling adzuki beans has inhibitory activity against alpha-glucosidase, alpha-amylase, maltase, sucrase, and isomaltase 15. The adzuki bean paste showed potential hypoglycemic activity in both normal mice and streptozotocin (STZ)-induced diabetic rats after an oral administration of sucrose, but did not show any effect on the blood glucose concentration after glucose administration, suggesting that the active fraction suppressed the postprandial blood glucose level by inhibiting alpha-glucosidase and alpha-amylase, irrespective of the endogenous blood insulin level. Wu et al. 16 have shown recently that a water-soluble extract of the adzuki beans could inhibit acetaminophen-induced liver damage. Han et al. 17 have reported the protective action of an adzuki extract against acetaminophen-induced hepatotoxicity via a hepatic γ-glutamylcysteinylglycine-mediated antioxidation/detoxification system in rat liver after four weeks of feeding.

Figure 1. Adzuki beans

adzuki beansFigure 2. Black adzuki beans

Black adzuki beans

Adzuki beans nutrition

Cooked adzuki beans are 66% water, 25% carbohydrates, including 7.3% dietary fiber, 8% protein, and contain negligible fat. In a 100 gram amount, cooked beans provide 128 Calories. Adzuki beans contain a moderate to high content (10% or more of the Daily Value, DV) of the B vitamin folate (30% DV) and several dietary minerals (11% to 27% DV).

The fatty acids compositions of total lipids and phospholipids in the adzuki beans were compared among the five cultivars (data not shown). The low total lipid contents of adzuki beans is similar to other foods – cereals as rice and rye, and legumes as bean, chick-pea and beans, that have less than 2% of fat, but with the advantage that the fat of the adzuki bean possesses a healthy Polyunsaturated fatty acids (PUFAs) omega-6/omega-3 which are essential fatty acids for human nutrition. Adzuki beans has good amounts of total unsaturated fatty acids which consisted mainly of linoleic (18:2n-6) acid, followed by α-linolenic (18:3n-3) and oleic (18:1n-9) acids, representing 70.6-73.8 wt-% and 69.9-72.6 wt-% for total lipids and phospholipids, respectively.

Table 1. Adzuki beans (mature seeds raw) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg13.44
Energykcal329
EnergykJ1377
Proteing19.87
Total lipid (fat)g0.53
Ashg3.26
Carbohydrate, by differenceg62.9
Fiber, total dietaryg12.7
Minerals
Calcium, Camg66
Iron, Femg4.98
Magnesium, Mgmg127
Phosphorus, Pmg381
Potassium, Kmg1254
Sodium, Namg5
Zinc, Znmg5.04
Copper, Cumg1.094
Manganese, Mnmg1.73
Selenium, Seµg3.1
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.455
Riboflavinmg0.22
Niacinmg2.63
Pantothenic acidmg1.471
Vitamin B-6mg0.351
Folate, totalµg622
Folic acidµg0
Folate, foodµg622
Folate, DFEµg622
Vitamin B-12µg0
Vitamin A, RAEµg1
Retinolµg0
Vitamin A, IUIU17
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Lipids
Fatty acids, total saturatedg0.191
Fatty acids, total monounsaturatedg0.05
18:1 undifferentiatedg0.05
Fatty acids, total polyunsaturatedg0.113
18:2 undifferentiatedg0.113
Fatty acids, total transg0
Cholesterolmg0
Phytosterolsmg76
Amino Acids
Tryptophang0.191
Threonineg0.674
Isoleucineg0.791
Leucineg1.668
Lysineg1.497
Methionineg0.21
Cystineg0.184
Phenylalanineg1.052
Tyrosineg0.591
Valineg1.023
Arginineg1.284
Histidineg0.524
Alanineg1.16
Aspartic acidg2.355
Glutamic acidg3.099
Glycineg0.756
Prolineg0.874
Serineg0.976
Isoflavones
Daidzeinmg0.35
Genisteinmg0.23
Glyciteinmg0
Total isoflavonesmg0.58
Biochanin Amg0
Formononetinmg0
Coumestrolmg0
Proanthocyanidin
Proanthocyanidin dimersmg19.4
Proanthocyanidin trimersmg18.1
Proanthocyanidin 4-6mersmg80
Proanthocyanidin 7-10mersmg75.7
Proanthocyanidin polymers (>10mers)mg252.9
[Source: United States Department of Agriculture Agricultural Research Service 18]

Table 2. Adzuki beans (mature seeds cooked or boiled without added salt) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg66.29
Energykcal128
EnergykJ536
Proteing7.52
Total lipid (fat)g0.1
Ashg1.33
Carbohydrate, by differenceg24.77
Fiber, total dietaryg7.3
Minerals
Calcium, Camg28
Iron, Femg2
Magnesium, Mgmg52
Phosphorus, Pmg168
Potassium, Kmg532
Sodium, Namg8
Zinc, Znmg1.77
Copper, Cumg0.298
Manganese, Mnmg0.573
Selenium, Seµg1.2
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.115
Riboflavinmg0.064
Niacinmg0.717
Pantothenic acidmg0.43
Vitamin B-6mg0.096
Folate, totalµg121
Folic acidµg0
Folate, foodµg121
Folate, DFEµg121
Vitamin B-12µg0
Vitamin A, RAEµg0
Retinolµg0
Vitamin A, IUIU6
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Lipids
Fatty acids, total saturatedg0.036
Fatty acids, total monounsaturatedg0.009
18:1 undifferentiatedg0.009
Fatty acids, total polyunsaturatedg0.021
18:2 undifferentiatedg0.021
Fatty acids, total transg0
Cholesterolmg0
Amino Acids
Tryptophang0.072
Threonineg0.255
Isoleucineg0.3
Leucineg0.632
Lysineg0.567
Methionineg0.079
Cystineg0.07
Phenylalanineg0.398
Tyrosineg0.224
Valineg0.387
Arginineg0.486
Histidineg0.198
Alanineg0.439
Aspartic acidg0.891
Glutamic acidg1.173
Glycineg0.286
Prolineg0.331
Serineg0.369
[Source: United States Department of Agriculture Agricultural Research Service 18]

Adzuki beans health benefits

Adzuki bean is a very important bean in the East Asia. Adzuki bean is used as a diuretic, antidote, and remedy for edema and beriberi in traditional Chinese medicine 19 and being prescribed for infection and inflammation of the appendix, kidney and bladder 20. Water and methanolic or ethanolic extracts of azuki bean have been demonstrated to up-regulate inducible nitric oxide synthase (iNOS) and to reduce blood pressure 21, decrease serum cholesterol levels 22 and ameliorate diabetes progression 23. Azuki bean seed coats, which are rich in polyphenols, were recently reported to attenuate vascular oxidative stress in spontaneously hypertensive rats 24. However, little is known about the molecular mechanisms of the beneficial effects of azuki bean. To date, only one study has reported the immunomodulatory mechanism of azuki bean extract: an ethanol extract inhibited nuclear factor (NF)-κB, activator protein (AP)-1, and cAMP response element-binding protein (CREB) activation in lipopolysaccharide (LPS)-, poly(I:C)- and pam3CSK-activated macrophages and blocked the activation of the upstream signalling molecules, including p38 and TAK1 25. Blockade of IL-6 activities with tocilizumab (anti-IL-6 receptor antibody) has been reported to significantly reduce disease activity in rheumatoid arthritis, indicating that IL-6 is strongly involved in the pathogenesis of rheumatoid arthritis 26. This study 27 showed that the inhibitory activity of adzuki beans on IL-6 signalling was associated with an anti-rheumatic effect by using a collagen-induced arthritis mice model. Oral administration of adzuki beans extract suppressed tissue damage occurring in collagen-induced arthritis. The adzuki beans extract triterpenoids — oleanolic acid and oleanolic acid acetate— have the potential to be an effective treatment for rheumatoid arthritis, but requires furhter investigation and studies in order to be considered for rheumatoid arthritis treatment.

Polyphenols are plant secondary metabolites and have attracted interest with health benefits 28. Genistein, a polyphenol compound, belongs to the category of isoflavones, and has been found almost every leguminous plants including adzuki beans (Figure 3). Early studies indicated that genistein protects age-associated degenerative disorders such as myocardial infarction (heart attack) 29, hepatic failure 30, diabetes, obesity 31 and brain damage 32. In addition, genistein proved to be effective in neuroprotection and bone loss in animal models via estrogen-mimicking activity 33.

Figure 3. Adzuki beans genistein

Adzuki beans genistein

[Source 34]

Phenolic compounds are resistant to oxidation and protect cell damage to prevent the risk of degenerative diseases thanks to antioxidative, anti-inflammatory, antiallergic and anticarcinogenic activities 35. There were 11 phenolic constituents identified in adzuki beans 36. Total phenolics are naturally produced during the growth and development of plants to protect themselves from biotic stresses such as diseases, insects and environmental stresses 35. Antioxidant activity is closely related to phenolic content 37. The change in total phenolic content in legumes during germination is illustrated in Table 3. The phenolic concentration dramatically increased in all legumes after five days of germination. In ungerminated grains, the content of total phenolics ranged from 5.80 (mung beans) to 18.21 (peanuts) mg GAE/g dry sample. After 5 days of sprouting, the phenolic content in mung beans, white cowpeas, soybeans and peanuts increased 2-fold, while that in black beans and adzuki beans showed about a 50% and 25% increase, respectively. In particular, peanuts had the highest concentration, which was 37.59 mg GAE/g, followed by soybeans (28.27 mg GAE/g), white cowpeas (19.46 mg GAE/g), adzuki beans (16.96 mg GAE/g), black beans (16.47 mg GAE/g), and mung beans (14.97 mg GAE/g). Adzuki beans and black beans are dark skin seeds that contain anthocyanidin pigments consisting of delphinidin, cyanidin, pelargonidin, malvidin, and petunidin 38.

Table 3. Total phenolic content (mg GAE/g dry weight) of ungerminated and germinated legumes

Black BeansMung BeansPeanutsAdzuki BeansSoybeansWhite Cowpeas
0 h11.74 ± 0.075.80 ± 0.0518.21 ± 0.1512.21 ± 0.0612.12 ± 0.097.79 ± 0.02
24 h13.17 ± 0.10 r11.47 ± 0.09 tu26.89 ± 0.11 f13.64 ± 0.17 q21.46 ± 0.05 i11.33 ± 0.09 u
48 h13.62 ± 0.07 q12.32 ± 0.36 s28.71 ± 0.16 d15.59 ± 0.05 n21.61 ± 0.11 i14.06 ± 0.08 p
72 h14.20 ± 0.18 p12.28 ± 0.13 s29.39 ± 0.04 c15.89 ± 0.05 n23.92 ± 0.08 h14.71 ± 0.07 °
96 h13.47 ± 1.17 qr12.47 ± 0.09 s30.34 ± 0.09 b16.57 ± 0.05 m24.75 ± 0.15 g16.29 ± 0.11 m
120 h16.47 ± 0.14 m14.97 ± 0.09 °37.59 ± 0.18 a16.96 ± 0.06 l28.27 ± 0.11 e19.46 ± 0.09 j

Note: Means ± SD (standard deviation) that do not share a superscript letter are significantly different at 95% confidential level.

[Source 36]

Table 4. Phenolic components and concentrations (µg/g dry weight) of legumes after 5-day germination

Phenolic componentsBlack BeansMung BeansPeanutsAdzuki BeansSoybeansWhite Cowpeas
Gallic acidndndndnd21.3 ± 2.9nd
Protocatechuic acidndnd15.1 ± 2.5 b2.2 ± 0.1 c41.5 ± 6.6 and
p-hydroxybenzoic acid24.1 ± 1.0 b15.9 ± 0.3 b16.8 ± 0.1 b19.5 ± 0.6 b66.6 ± 0.8 and
Vanillic acid43.8 ± 0.8 c5.2 ± 0.7e67.6 ± 0.8 b25.2 ± 0.9 d189.2 ± 10.1 and
Caffeic acidndndndndnd70.8 ± 6.6
Syringic acid79.8 ± 1.7 b16.7 ± 1.8 cnd23.8 ± 0.8 c327.5 ± 14.9 a30.4 ± 5.3 c
Vanillin12.4 ± 0.8 b14.2 ± 0.5 bnd15.9 ± 2.9 bnd28.9 ± 3.3 a
Ferulic acidnd26.6 ± 2.8 c330.3 ± 16.0 a15.7 ± 1.6 c72.9 ± 5.6 b18.2 ± 0.8 c
Sinapic acid109.1 ± 0.5 c163.5 ± 3.8 b247.9 ± 21.1 a150.7 ± 4.6 b218.1 ± 7.5 a99.65 ± 7.4 c
p-coumaric acid72.1 ± 3.1 b288.7 ± 3.6 and14.4 ± 2.8 c18.1 ± 4.5 c81.95 ± 0.65 b
Benzoic acid253.5 ± 26.7 b636.0 ± 2.4 and124.8 ± 51.9 cnd199.5 ± 36.4 bc
Ellagic acid54.4 ± 3.9 nsnd126.2 ± 89.3 ns30.3 ± 4.0 ns59.6 ± 2.4 ns48.3 ± 6.5 ns
Cinnamic acid14.85 ± 2.9 ab4.0±0.1 b62.9 ± 35.6 a3.1 ± 0.2 b36.2 ± 1.5 ab12.5 ± 3.2 ab

Note: Means ± SD (standard deviation) that do not share a letter in the same row are significantly different at 95% confidential level. ns: not significantly different; nd: not detected.

[Source 36]

Table 5. Antioxidant activities of 5-day germinated legume extracts

SampleDPPH• Scavenging (%)Reducing Power (%)
Black beans7.44 ± 0.39 f64.92 ± 0.57 c
Mung beans17.46 ± 0.60 d26.45 ± 0.95 f
Peanuts32.51 ± 0.54 a84.48 ± 1.24 a
Adzuki beans20.80 ± 0.39 c42.51 ± 1.24 e
Soybeans26.94 ± 0.71 b75.08 ± 1.18 b
White cowpeas11.17 ± 0.63 e61.53 ± 0.68 d

Note: Means ± SD that do not share a superscript letter are significantly different at 95% confidential level.

The antioxidant activities of germinated legumes were evaluated by the DPPH method and the reducing power assay, as shown in Table 5. It was found that the six legume extracts had different antioxidant activity levels at a 0.1 mg/mL dose. In particular, peanuts had the highest antioxidant activity at 32.51%, which was significantly different from the others, while black beans showed the lowest antioxidant activity (7.44%). The reducing power of germinated peanuts obtained maximum activity (84.48%) compared to other studied legumes (Table 5), whereas the lowest antioxidant activity was mung beans (26.45%). Although adzuki beans had higher DPPH- scavenging activity than black beans and white cowpeas, the reducing power capacity of adzuki beans was, in contrast, significantly lower than that of black beans and white cowpeas (Table 5).

In this study, peanuts contained a maximum concentration of phenolics, which may result in the strongest antioxidant activity of the legume. Furthermore, according to Corral-Aguayo et al. 39, when compared to the antioxidant activity, resveratrol had stronger activity than flavonoids. In addition, the main substances in soybean phenolics were flavonoids, whereas, in other legumes (chickpeas and black, red, and white cowpeas), the major components were phenolic acids 40. This may explain why soybeans had greater antioxidant activities than the other four legumes in the DPPH assay.

[Source 36]

Although no evidence is available for the mechanism of action of common beans on other kinds of cancer, the antiproliferative effect of legumes, including Adzuki beans, has been explored 41. Adzuki bean exhibited the strongest antiproliferative properties in a dose-dependent manner against all digestive system cancer cell lines (CAL27, AGS, HepG2, SW480 and Caco-2), ovary cancer cell SK-OV-3 and breast cancer cell MCF-7 among all legumes tested 42. Nakaya et al. 43 suggested that adzuki bean and its heat-stable extract is immunopotentiating foods that can be used as dietary supplements for cancer prevention and immunotherapy. Adzuki bean stimulates differentiation of bone marrow cells into immature dendritic cells with the greatest efficacy compared to 30 types of edible beans with biological activity. The level of IL-6 produced by sequential treatment of dendritic cells with Adzuki extract and lipopolysaccharide was the highest among the examined beans. Adzuki beans extract also inhibited the growth of human leukemia U937 cells, leading to induction of apoptosis. Further research is warranted regarding the implications and the molecular mechanisms in which adzuki beans and their bioactive compounds modulate the development of different types of cancer.

Hot-water adzuki beans extract contains such chemical compounds as catechins and saponins which are well-known bioactive ingredients 44. Ito and colleagues have previously reported that the 40% ethanol-eluted fraction of hot-water adzuki beans extract and HP-20 resin possessed antitumor 45, antioxidative 46 anti-metastatic 46 and anti-diabetic activities, 47, lowered the serum cholesterol levels 48 and enhanced melanogenesis 49. The color of hot-water adzuki beans extract originates from (+)-catechin 50. Choi et al. 51 and Nakamura et al. 52 have reported that (+)-catechin and green tea catechin regulated osteoblast and osteoclast differentiation.

Obesity increases the risk of metabolic disorders such as hyperglycemia, hyperlipidemia, hypercholesterolemia, and diabetes 53. Both an increased number of adipocytes (fat cells), due to enhanced differentiation of preadipocytes into adipocytes, and increased adipocyte size due to lipid accumulation are shown to participate in the expansion of adipose tissue 54. Numerous studies have suggested that oxidative stress may be the linking mechanism in the pathway leading from obesity to obesity-related chronic diseases 55. Black adzuki bean exhibited the greatest antioxidant activity compared to 20 other kinds of adzuki beans 56. Adzuki beans have been evaluated as potential remedies for hypercholesterolemia, hyperglycemia, and inflammation in mice and rats 57, 58 and preliminary data have shown that black adzuki beans inhibit proliferation and mitotic clonal expansion and subsequently inhibit the adipogenesis of 3T3-L1 cells 59. Although recent studies have reported evidence that the adzuki beans affect the regulation of lipid metabolism, it remains to be determined whether they may be effective in overcoming obesity by regulating appetite and satiety. Chau et al. 60 observed no changes in serum total cholesterol, LDL “bad” cholesterol and HDL “good” cholesterol levels in hamsters fed a hypercholesterolemic diet by using a adzuki bean protein concentrate.

In a study on mouse, a hot-water extract of adzuki beans was found to stimulate tyrosinase activity in cultured mouse B16 melanoma cells and hair color pigmentation in C3H mice 61. At concentrations of 1–3 mg/ml, adzuki beans hot-water extract stimulated melanogenesis without inhibiting cell growth. During this effect, WEx activated tyrosinase-inducing activity in the cells, but did not activate tyrosinase, which exists at an intracellular level. In this study, adzuki beans hot-water extract increased cyclic adenosine-3′,5′-monophospate (cAMP) content in the cells and protein kinase A (PKA) activity, and stimulated translocation of cytosolic protein kinase C to the membrane-bound protein kinase C 61. These results suggest that the addition of adzuki beans hot-water extract activates the adenylcyclase and protein kinase pathways and, as a result, stimulates melanogenesis. Adzuki beans hot-water extract was found to have pigmentation activity on hair color in C3H mice. This effect might be useful in anti-graying, protecting human skin from irradiation 61.

Azuki beans contain polyphenols such as proanthocyanidins that exhibit potential radical scavenging activities 62. Spontaneously hypertensive rats with approximately 200 mm Hg systolic blood pressure were randomly divided into 2 groups fed either 0% or 0.9% azuki bean extract-containing diet. Azuki bean extract reduced the elevated blood pressure and increased nitric oxide (NO) production in long-term treatment 63.

Osteoporosis is a global public health problem thought to be caused by an imbalance in bone metabolism. Bone metabolic balance (bone resorption and bone formation) is maintained by osteoclasts and osteoblasts 64. Aging is accompanied by disruption in bone metabolism leading to osteoporosis; the risk is particularly high in women who tend to lose bone after menopause. Aging-associated degeneration of the osteoblast function also reduces bone mass, as does malnutrition or under-nutrition (a deficiency of micronutrients and macronutrients). This study 65 the 40% ethanol fraction in combination with a hot-water adzuki beans extract was examined for its effect on osteoblast and osteoclast differentiation. Adzuki beans extract -treated mice preosteoblast MC3T3-E1 cells exhibited significantly elevated alkaline phosphatase activity and mineralization. Adzuki beans extract facilitated osteoblast differentiation by up-regulating such osteoblast differentiation-related molecules as runt-related transcription factor 2, distal-less homeobox 5, and osterix via p38 mitogen-activated protein kinase. In summary this study 65 suggest that 40% ethanol-eluted fraction of hot-water adzuki beans extract could be used to treat senile osteoporosis and postmenopausal osteoporosis. Lee et al. have reported that the consumption of such a legume as adzuki improved the levels of bone markers in ovariectomized rats 66. However what the active compound is in the hot-water adzuki beans extract have yet to be elucidated. Further studies are needed to verify the effect of 40% ethanol-eluted fraction of hot-water adzuki beans extract on osteoporosis in animal models.

  1. Kang YJ, Satyawan D, Shim S, et al. Draft genome sequence of adzuki bean, Vigna angularis. Scientific Reports. 2015;5:8069. doi:10.1038/srep08069. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389050/[]
  2. Cereals, legumes, and chronic disease risk reduction: evidence from epidemiologic studies. Kushi LH, Meyer KA, Jacobs DR Jr. Am J Clin Nutr. 1999 Sep; 70(3 Suppl):451S-458S. https://www.ncbi.nlm.nih.gov/pubmed/10479217/[]
  3. Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis. Afshin A, Micha R, Khatibzadeh S, Mozaffarian D. Am J Clin Nutr. 2014 Jul; 100(1):278-88. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144102/[][]
  4. Cereal fiber and whole-grain intake are associated with reduced progression of coronary-artery atherosclerosis in postmenopausal women with coronary artery disease. Erkkilä AT, Herrington DM, Mozaffarian D, Lichtenstein AH. Am Heart J. 2005 Jul; 150(1):94-101. https://www.ncbi.nlm.nih.gov/pubmed/16084154/[]
  5. Impact of soy isoflavones on the epigenome in cancer prevention. Pudenz M, Roth K, Gerhauser C. Nutrients. 2014 Oct 15; 6(10):4218-72. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210915/[]
  6. Rubatzky V. E., Yamaguchi M., Rubatzky V. & Yamaguchi M. World vegetables: principles, production, and nutritive values. Chapman & Hall New York, 1997.[]
  7. Tomooka N., Vaughan D. & Moss H. The Asian Vigna: genus Vigna subgenus Ceratotropis genetic resources. Kluwer, Dordrecht, 2002.[]
  8. Lee G.-A. Archaeological perspectives on the origins of azuki (Vigna angularis). Holocene 23, 453–459, 2013.[]
  9. McClary, N., Raney, T. L., and Lumpkin, T. A., ‘‘Japanese Food Marketing Channels: A Case Study of Azuki Beans and Azuki products’’, Washington State University, Impact Center, Pullman, pp. 41, 1989[]
  10. Tjahjadi C., Lin S., Breene W.N. Isolation and Characterization of Adzuki Beans (Vigna angularis cv. Takara) Protein. J. Food Sci. 1988;53:1438–1443. doi: 10.1111/j.1365-2621.1988.tb09294.x[]
  11. Yoshida H, Tomiyama Y, Yoshida N, Shibata K, Mizushina Y. Regiospecific Profiles of Fatty Acids in Triacylglycerols and Phospholipids from Adzuki Beans (Vigna angularis). Nutrients. 2010;2(1):49-59. doi:10.3390/nu20100049. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257609/[]
  12. Itoh T., Itoh Y., Mizutani M., Fujishiro K., Furuichi Y., Komiya T., Hibasam H. A Hot-Water Extract of Adzuki (Vigna angularis) Induces Apotosis in Cultured Human Stomach Cancer Cells. Nippon Shokuhin Kagaku Kogaku Kaishi. 2002;49:339–344[]
  13. Hot-water extracts from adzuki beans (Vigna angularis) suppress not only the proliferation of KATO III cells in culture but also benzo(a)pyrene-induced tumorigenesis in mouse forestomatch. Itoh T, Itoh Y, Mizutani M, Fujishiro K, Furuichi Y, Komiya T, Hibasami H. J Nutr Sci Vitaminol (Tokyo). 2004 Aug; 50(4):295-9. https://www.ncbi.nlm.nih.gov/pubmed/15527074/[]
  14. Tompson, L. U., Yoon, J. H., and Jenkins, D. J. A., Relationship between polyphenol intake and blood glucose response of normal and diabetic individuals. Am. J. Clin. Nutr.,39, 745–751, 1984[]
  15. Suppressive effect of a hot water extract of adzuki beans (Vigna angularis) on hyperglycemia after sucrose loading in mice and diabetic rats. Biosci Biotechnol Biochem. 2004 Dec;68(12):2421-6. https://www.tandfonline.com/doi/pdf/10.1271/bbb.68.2421[]
  16. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. J Agric Food Chem. 2004 Jun 16; 52(12):4026-37. https://www.ncbi.nlm.nih.gov/pubmed/15186133/[]
  17. Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver. Han KH, Fukushima M, Ohba K, Shimada K, Sekikawa M, Chiji H, Lee CH, Nakano M. J Nutr Sci Vitaminol (Tokyo). 2004 Oct; 50(5):380-3. https://www.ncbi.nlm.nih.gov/pubmed/15754502/[]
  18. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][]
  19. ‘Dictionary of Chinese Crude Drugs’’ (in Chinese), Chiang Su New Medical College, Shanghai Scientific Technologic Publisher, Shanghai, pp. 1090 ;1977[]
  20. Antibacterial activity of plant extracts from azuki beans (Vigna angularis) in vitro. Phytother Res. 2006 Feb;20(2):162-4. https://www.ncbi.nlm.nih.gov/pubmed/16444673[]
  21. Polyphenol-containing azuki bean (Vigna angularis) extract attenuates blood pressure elevation and modulates nitric oxide synthase and caveolin-1 expressions in rats with hypertension. Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):491-7. doi: 10.1016/j.numecd.2008.09.007. Epub 2009 Jan 20. https://www.ncbi.nlm.nih.gov/pubmed/19157815[]
  22. Lowering serum cholesterol level by feeding a 40% ethanol-eluted fraction from HP-20 resin treated with hot water extract of adzuki beans (Vigna angularis) to rats fed a high-fat cholesterol diet. Nutrition. 2009 Mar;25(3):318-21. doi: 10.1016/j.nut.2008.08.011. Epub 2008 Nov 26. https://www.ncbi.nlm.nih.gov/pubmed/19036561[]
  23. Hypoglycemic effect of hot-water extract of adzuki (Vigna angularis) in spontaneously diabetic KK-A(y) mice. Hypoglycemic effect of hot-water extract of adzuki (Vigna angularis) in spontaneously diabetic KK-A(y) mice. https://www.ncbi.nlm.nih.gov/pubmed/18929464[]
  24. Polyphenol-containing azuki bean (Vigna angularis) seed coats attenuate vascular oxidative stress and inflammation in spontaneously hypertensive rats. J Nutr Biochem. 2011 Jan;22(1):16-21. doi: 10.1016/j.jnutbio.2009.11.004. Epub 2010 Feb 25. https://www.ncbi.nlm.nih.gov/pubmed/20185287[]
  25. Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. https://www.ncbi.nlm.nih.gov/pubmed/21821108[]
  26. Anti-interleukin-6 receptor antibody therapy in rheumatic diseases. Endocr Metab Immune Disord Drug Targets. 2006 Dec;6(4):373-81. https://www.ncbi.nlm.nih.gov/pubmed/17214583[]
  27. Vigna angularis inhibits IL-6-induced cellular signalling and ameliorates collagen-induced arthritis, Rheumatology, Volume 53, Issue 1, 1 January 2014, Pages 56–64, https://doi.org/10.1093/rheumatology/ket302[]
  28. Dietary phenolics: chemistry, bioavailability and effects on health. Crozier A, Jaganath IB, Clifford MN. Nat Prod Rep. 2009 Aug; 26(8):1001-43. https://www.ncbi.nlm.nih.gov/pubmed/19636448/[]
  29. Genistein promotes endothelial colony-forming cell (ECFC) bioactivities and cardiac regeneration in myocardial infarction. Lee SH, Lee JH, Asahara T, Kim YS, Jeong HC, Ahn Y, Jung JS, Kwon SM. PLoS One. 2014; 9(5):e96155. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022670/[]
  30. Protective effect of genistein on lipopolysaccharide/D-galactosamine- induced hepatic failure in mice. Lin X, Zhang S, Huang R, Wei L, Liang C, Chen Y, Lv S, Liang S, Wu X, Huang Q. Biol Pharm Bull. 2014; 37(4):625-32. https://www.ncbi.nlm.nih.gov/pubmed/24818258/[]
  31. Genistein: a promising therapeutic agent for obesity and diabetes treatment. Behloul N, Wu G. Eur J Pharmacol. 2013 Jan 5; 698(1-3):31-8. https://www.sciencedirect.com/science/article/pii/S0014299912009442[]
  32. Genistein attenuates brain damage induced by transient cerebral ischemia through up-regulation of ERK activity in ovariectomized mice. Wang S, Wei H, Cai M, Lu Y, Hou W, Yang Q, Dong H, Xiong L. Int J Biol Sci. 2014; 10(4):457-65. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979998/[]
  33. Effects of estradiol and genistein on the insulin signaling pathway in the cerebral cortex of aged female rats. Morán J, Garrido P, Cabello E, Alonso A, González C. Exp Gerontol. 2014 Oct; 58():104-12. https://www.ncbi.nlm.nih.gov/pubmed/25086228/[]
  34. Lee EB, Ahn D, Kim BJ, et al. Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans. Biomolecules & Therapeutics. 2015;23(1):77-83. doi:10.4062/biomolther.2014.075. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286753/[]
  35. Phenolic composition and inhibitory effect against oxidative DNA damage of cooked cowpeas as affected by simulated in vitro gastrointestinal digestion. Nderitu AM, Dykes L, Awika JM, Minnaar A, Duodu KG. Food Chem. 2013 Dec 1; 141(3):1763-71. https://www.ncbi.nlm.nih.gov/pubmed/23870889/[][]
  36. Khang DT, Dung TN, Elzaawely AA, Xuan TD. Phenolic Profiles and Antioxidant Activity of Germinated Legumes. Vinson J, Smith CJ, eds. Foods. 2016;5(2):27. doi:10.3390/foods5020027. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302343/[][][][]
  37. Dynamic changes in phenolic compounds and antioxidant activity in oats (Avena nuda L.) during steeping and germination. Xu JG, Tian CR, Hu QP, Luo JY, Wang XD, Tian XD. J Agric Food Chem. 2009 Nov 11; 57(21):10392-8. https://www.ncbi.nlm.nih.gov/pubmed/19827789/[]
  38. Böhm H.G. In: Anthocyanins in Fruits, Vegetables and Grains. Miniati M.E., editor. CRC Press; Boca Raton, FL, USA; Ann Arbor, MI, USA; London, UK; Tokyo, Japan: 1993[]
  39. Correlation between some nutritional components and the total antioxidant capacity measured with six different assays in eight horticultural crops. Corral-Aguayo RD, Yahia EM, Carrillo-Lopez A, González-Aguilar G. J Agric Food Chem. 2008 Nov 26; 56(22):10498-504. https://www.ncbi.nlm.nih.gov/pubmed/18956873/[]
  40. Sosulski F., Krygier K., Hogge L. Free, esterified, and insoluble-bound phenolic acids. 3. Composition of phenolic acids in cereal and potato flours. J. Agric. Food. Chem. 1982;30:337–340. doi: 10.1021/jf00110a030[]
  41. Comparative study on antiproliferation properties and cellular antioxidant activities of commonly consumed food legumes against nine human cancer cell lines. Xu B, Chang SK. Food Chem. 2012 Oct 1; 134(3):1287-96. https://www.ncbi.nlm.nih.gov/pubmed/25005945/[]
  42. Campos-Vega R, Oomah BD, Loarca-Piña G, Vergara-Castañeda HA. Common Beans and Their Non-Digestible Fraction: Cancer Inhibitory Activity—An Overview. Foods. 2013;2(3):374-392. doi:10.3390/foods2030374. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302293/[]
  43. Stimulation of dendritic cell maturation and induction of apoptosis in leukemia cells by a heat-stable extract from azuki bean (Vigna angularis), a promising immunopotentiating food and dietary supplement for cancer prevention. Nakaya K, Nabata Y, Ichiyanagi T, An WW. Asian Pac J Cancer Prev. 2012; 13(2):607-11. https://www.ncbi.nlm.nih.gov/pubmed/22524832/[]
  44. Hirao K, Yumoto H, Nakanishi T, Mukai K, Takahashi K, Takegawa D, Matsuo T. Life Sci. 2010;86:654–660.[]
  45. Itoh T, Itoh Y, Mizutani M, Fujishiro K, Furuichi Y, Komiya T, Hibasami H. Nippon Shokuhin Kagaku Kougaku Kaishi. 2002;49:339–344. Japanese[]
  46. Itoh T, Umekawa H, Furuichi Y. Biosci. Biotechnol. Biochem. 2005;69:448–454.[][]
  47. Itoh T, Kita N, Kurokawa Y, Kobayashi M, Horio F, Furuichi Y. Biosci. Biotechnol. Biochem. 2004;68:2421–2426[]
  48. Itoh T, Furuich Y. Nutrition. 2009;25:873–882.[]
  49. Itoh T, Furuichi Y. Biosci. Biotechnol. Biochem. 2005;69:873–882.).) 40% ethanol-eluted fraction of hot-water adzuki beans has also suppressed antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells ((Itoh T, Hori Y, Atsumi T, Toriizuka K, Nakamura M, Maeyama T, Ando M, Tsukamasa Y, Ida Y, Furuichi Y. Phytother. Res. 2013;26:1003–1011.[]
  50. Itoh T, Hori Y, Atsumi T, Toriizuka K, Nakamura M, Maeyama T, Ando M, Tsukamasa Y, Ida Y, Furuichi Y. Phytother. Res. 2013;26:1003–1011[]
  51. Choi EM, Hwang JK. Biol. Pharm. Bull. 2003;26:523–526.[]
  52. Nakamura H, Ukai T, Yoshimura A, Kozuka Y, Yoshioka H, Yoshinaga Y, Abe Y, Hara Y. J. Periodontal Res. 2010;45:23–30.[]
  53. Rayalam S., Della-Fera M.A., Baile C.A. Phytochemicals and regulation of the adipocyte life cycle. J. Nutr. Biochem. 2008;19:717–726. doi: 10.1016/j.jnutbio.2007.12.007. https://www.ncbi.nlm.nih.gov/pubmed/18495457[]
  54. Kim C.Y., Le T.T., Chen C., Cheng J.X., Kim K.H. Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion. J. Nutr. Biochem. 2011;22:910–920. doi: 10.1016/j.jnutbio.2010.08.003 https://www.ncbi.nlm.nih.gov/pubmed/21189228[]
  55. Shelly H., Corene C., Shi S., Xiuxiu S., Kequan Z. Effects of grape pomace antioxidant extract on oxidative stress and inflammation in diet induced obese mice. J. Agric. Food Chem. 2010;25:11250–11256. https://www.ncbi.nlm.nih.gov/pubmed/20929236[]
  56. Kim M, Park J-E, Song S-B, Cha Y-S. Effects of Black Adzuki Bean (Vigna angularis) Extract on Proliferation and Differentiation of 3T3-L1 Preadipocytesinto Mature Adipocytes. Nutrients. 2015;7(1):277-292. doi:10.3390/nu7010277. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303839/[]
  57. Shigenori N, Yusuke S, Chihiro S, Jun K, Hiroshi K, Kazunori H, et al. Suppression of serum cholesterol levels in mice by adzuki bean polyphenols. Food Sci Technol Res. 2008;14:217–20.[]
  58. Carai M. Potential efficacy of preparations derived from Phaseolus vulgaris in the control of appetite, energy intake, and carbohydrate metabolism. Diabetes Metab Syndr Obes. 2009;2:145–53.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048011/[]
  59. Kim M, Park JE, Song SB, Cha YS. Effects of black adzuki bean (Vigna angularis) extract on proliferation and differentiation of 3T3-L1 preadipocytes into mature adipocytes. Nutrients. 2015;7:277–92 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303839/[]
  60. Chau C-F, Cheung PCK & Wong Y-S (1998) Hypocholesterolemic effects of protein concentrate from three Chinese indigenous legume seeds. J Agric Food Chem 46, 3698–3701[]
  61. Hot-Water Extracts from Adzuki Beans (Vigna angularis) Stimulate Not Only Melanogenesis in Cultured Mouse B16 Melanoma Cells but Also Pigmentation of Hair Color in C3H Mice. Biosci. Biotechnol. Biochem.,69(5), 873–882, 2005https://www.jstage.jst.go.jp/article/bbb/69/5/69_5_873/_pdf/-char/en[][][]
  62. Polyphenol-containing azuki bean (Vigna angularis) extract attenuates blood pressure elevation and modulates nitric oxide synthase and caveolin-1 expressions in rats with hypertension. Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):491-7. doi: 10.1016/j.numecd.2008.09.007. Epub 2009 Jan 20. https://www.nmcd-journal.com/article/S0939-4753(08)00191-9/fulltext[]
  63. Polyphenol-containing azuki bean (Vigna angularis) extract reduces blood pressure elevation and modulates nitric oxide synthase and caveolin-1 expressions in rats with hypertension. Nutr Metab Cardiovasc Dis. 2009 Sep;19(7):491-7. doi: 10.1016/j.numecd.2008.09.007. Epub 2009 Jan 20. https://www.nmcd-journal.com/article/S0939-4753(08)00191-9/fulltext[]
  64. Manolagas SC. Endocr. Rev. 2000;21:115–137.[]
  65. Regulation of the differentiation of osteoblasts and osteoclasts by a hot-water extract of adzuki beans (Vigna angularis), Bioscience, Biotechnology, and Biochemistry, 78:1, 92-99, DOI: 10.1080/09168451.2014.877182 https://www.tandfonline.com/doi/full/10.1080/09168451.2014.877182[][]
  66. Lee SH, Jin N, Paik DJ, Kim DY, Chung IM, Park Y. Nutr. Res. 2011;31:397–403.[]
read more

Are pistachio nuts good for you?

pistachio nuts

What are pistachio nuts

Pistachio (Pistacia vera L.), a member of the cashew (Anacardiaceae) family, is a small tree cultivated in Iran, Turkey, United States, Syria, Italy, Tunisia, and Greece 1. Iran is one of the biggest producers and exporters of pistachio nuts 2. Fruit of Pistacia vera (pistachio) is used all over the world. Pistachios are globally distributed and consumed as a healthy snack. Pistachios can also be added to many savory dishes such as pastas, marinades and crusts for meat entrees, salsas, and stir-fries as well as a topping for salads, yogurts, and dips. Moreover, different parts of pistachio plant (Pistacia vera L.), including flower, leaf, seed and resins derived from stem, have pharmacological properties like antimicrobial, antioxidant and anti-inflammatory activities 3. Records of the consumption of pistachio as a food date to 7000 BC 4. The tree produces pistachio seeds (nuts) that are widely consumed as food. Pistachio nuts are a rich source of phenolic compounds, known for their high antioxidant activity, and contained not only in the seeds but also in the skin 5. Unfortunately, pistachio nut is also responsible for triggering moderate to severe IgE-mediated reactions in allergic individuals 6. Currently, pistachio nut allergy has gained some special attention, mainly due to its intrinsic relation with cashew nut allergy.

Pistachio is a desert plant that is highly adaptable to abiotic stresses and considered as a tolerant species against drought and salt stresses and is highly tolerant of saline soil. Although pistachio is categorized as a salt-tolerant glycophyte species, its yield is dramatically constrained under the high salinity conditions 7. It has been reported to grow well when irrigated with water having 3,000–4,000 ppm of soluble salts. Pistachio trees are fairly hardy in the right conditions and can survive temperatures ranging between −10 °C (14 °F) in winter and 48 °C (118 °F) in summer. They need a sunny position and well-drained soil. Pistachio trees do poorly in conditions of high humidity and are susceptible to root rot in winter if they get too much water and the soil is not sufficiently free-draining. Long, hot summers are required for proper ripening of the fruit. Pistachio (Pistacia vera L.) often is confused with other species in the genus Pistacia that are also known as pistachio. These other species can be distinguished by their geographic distributions (in the wild) and their seeds which are much smaller and have a soft shell.

To prevent fatty acids in pistachios from oxidation, store pistachios in an airtight container in the refrigerator at 40°F (4°C) for up to 1 year. At room temperature 68°F (20°C), they should be kept in a dry environment and will last several months.

Figure 1. Pistachio

Pistachio

Figure 2. Pistachio nuts

pistachio nuts

Pistachio nutrition

Pistachio nuts are a nutritionally dense food. In a 100 gram serving, pistachio nuts provide 560 calories and are a rich source (20% or more of the Daily Value or DV) of protein, dietary fiber, several dietary minerals (i.e, potassium, phosphorus, magnesium, calcium) and the B vitamins, thiamin and especially vitamin B6 (Pyridoxine) at 131% DV. Pistachio nuts are a good source (10–19% DV) of calcium, riboflavin, vitamin A, vitamin B5, vitamin C, folate, vitamin E (especially γ-tocopherol), and vitamin K. Pistachios are also a good source of vegetable protein (about 21% of total weight), with an essential amino acid ratio higher than most other commonly consumed nuts (ie, almonds, walnuts, pecans, and hazelnuts), and they have a high percentage of branched chain amino acids 8. The amount of total carbohydrates is low to moderate (about 29% by weight), but they are richer in fiber than other nuts with a 10% by weight of insoluble forms and 0.3% of soluble forms (Table 3).

Pistachio nut is high in polyunsaturated fatty acids (PUFAs), monounsaturated fatty acids (MUFAs), flavonoids, and proanthocyanidins 9 and carotenoids (lutein, β-carotene, and γ-tocopherol) content. Saturated fatty acids include palmitic acid (10% of total) and stearic acid (2%). Oleic acid is the most common monounsaturated fatty acid (51% of total fat) and linoleic acid, a polyunsaturated fatty acid, is 31% of total fat. Relative to other tree nuts (see Table 3 below), pistachios have a lower amount of fat and calories but higher amounts of potassium, vitamin K, γ-tocopherol, and certain phytochemicals such as carotenoids and phytosterols. Dry roasted pistachios have a lower fat content (45.82 g/100 g), which is composed mainly of saturated fatty acid (5.6 g), polyunsaturated fatty acid (13.3 g), and monounsaturated fatty acid (24.5 g).

Moreover, pistachios are also a rich source of lutein and zeaxanthin (xanthophyll carotenoids) and phenolic compounds, including anthocyanins, flavonoids, and proanthocyanidins, and their antioxidant capacity is considerable. Pistachios are the nuts that have the highest content of phytosterols, including stigmasterol, campesterol, and β-sitosterol 10. This complete and diverse set of micronutrients and macronutrients means that pistachio nuts are potentially one of the more health-promoting foods. Their beneficial properties, based on pistachios’ specific macronutrient, micronutrient and bioactive molecules will remain unchanged even after cooked. Moreover, other properties such as their contribution to the glycemic index and glycemic load of a particular meal would be improved by their inclusion.

Table 1. Pistachio nuts (raw) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg4.37
Energykcal560
EnergykJ2342
Proteing20.16
Total lipid (fat)g45.32
Ashg2.99
Carbohydrate, by differenceg27.17
Fiber, total dietaryg10.6
Sugars, totalg7.66
Sucroseg6.87
Glucose (dextrose)g0.32
Fructoseg0.24
Lactoseg0
Maltoseg0.17
Starchg1.67
Minerals
Calcium, Camg105
Iron, Femg3.92
Magnesium, Mgmg121
Phosphorus, Pmg490
Potassium, Kmg1025
Sodium, Namg1
Zinc, Znmg2.2
Copper, Cumg1.3
Manganese, Mnmg1.2
Selenium, Seµg7
Fluoride, Fµg3.4
Vitamins
Vitamin C, total ascorbic acidmg5.6
Thiaminmg0.87
Riboflavinmg0.16
Niacinmg1.3
Pantothenic acidmg0.52
Vitamin B-6mg1.7
Folate, totalµg51
Folic acidµg0
Folate, foodµg51
Folate, DFEµg51
Vitamin B-12µg0
Vitamin A, RAEµg26
Retinolµg0
Carotene, betaµg305
Carotene, alphaµg10
Cryptoxanthin, betaµg0
Vitamin A, IUIU516
Lutein + zeaxanthinµg2903
Vitamin E (alpha-tocopherol)mg2.86
Tocopherol, betamg0
Tocopherol, gammamg20.41
Tocopherol, deltamg0.8
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Lipids
Fatty acids, total saturatedg5.907
04:00:00g0
6:0g0.012
8:0g0
10:0g0.004
12:0g0
13:0g0
14:0g0.019
15:0g0
16:0g5.265
17:0g0.009
18:0g0.478
20:0g0.046
22:0g0.04
24:0g0
Fatty acids, total monounsaturatedg23.257
14:1g0
16:1 undifferentiatedg0.495
18:1 undifferentiatedg22.674
20:1g0.089
22:1 undifferentiatedg0
24:1 cg0
Fatty acids, total polyunsaturatedg14.38
18:2 undifferentiatedg14.091
18:2 n-6 c,cg14.091
18:3 undifferentiatedg0.289
18:04:00g0
20:2 n-6 c,cg0
20:3 undifferentiatedg0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Fatty acids, total transg0
Cholesterolmg0
Phytosterolsmg214
Stigmasterolmg5
Campesterolmg10
Beta-sitosterolmg198
Amino Acids
Tryptophang0.251
Threonineg0.684
Isoleucineg0.917
Leucineg1.604
Lysineg1.138
Methionineg0.36
Cystineg0.292
Phenylalanineg1.092
Tyrosineg0.509
Valineg1.249
Arginineg2.134
Histidineg0.512
Alanineg0.973
Aspartic acidg1.884
Glutamic acidg4.3
Glycineg1.009
Prolineg0.938
Serineg1.283
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
Anthocyanidins
Cyanidinmg7.3
Petunidinmg0
Delphinidinmg0
Malvidinmg0
Pelargonidinmg0
Peonidinmg0
Flavan-3-ols
(+)-Catechinmg3.6
(-)-Epigallocatechinmg2
(-)-Epicatechinmg0.8
(-)-Epicatechin 3-gallatemg0
(-)-Epigallocatechin 3-gallatemg0.4
(+)-Gallocatechinmg0
Flavanones
Hesperetinmg0
Naringeninmg0
Flavones
Apigeninmg0
Luteolinmg0
Flavonols
Myricetinmg0
Quercetinmg1.5
Isoflavones
Daidzeinmg1.87
Genisteinmg1.75
Glyciteinmg0
Total isoflavonesmg3.63
Formononetinmg0
Coumestrolmg0.01
Proanthocyanidin
Proanthocyanidin dimersmg13.3
Proanthocyanidin trimersmg10.5
Proanthocyanidin 4-6mersmg42.2
Proanthocyanidin 7-10mersmg37.9
Proanthocyanidin polymers (>10mers)mg122.5
[Source: United States Department of Agriculture Agricultural Research Service 11]

Table 2. Pistachio nuts (dry roasted without added salt) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg1.85
Energykcal572
EnergykJ2392
Proteing21.05
Total lipid (fat)g45.82
Ashg3
Carbohydrate, by differenceg28.28
Fiber, total dietaryg10.3
Sugars, totag7.74
Sucroseg7.09
Glucose (dextrose)g0.25
Fructoseg0.22
Lactoseg0
Maltoseg0.13
Galactoseg0.05
Starchg1.38
Minerals
Calcium, Camg107
Iron, Femg4.03
Magnesium, Mgmg109
Phosphorus, Pmg469
Potassium, Kmg1007
Sodium, Namg6
Zinc, Znmg2.34
Copper, Cumg1.293
Manganese, Mnmg1.243
Selenium, Seµg10
Vitamins
Vitamin C, total ascorbic acidmg3
Thiaminmg0.695
Riboflavinmg0.234
Niacinmg1.373
Pantothenic acidmg0.513
Vitamin B-6mg1.122
Folate, totalµg51
Folic acidµg0
Folate, foodµg51
Folate, DFEµg51
Choline, totalmg71.4
Betainemg0.8
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg13
Retinolµg0
Carotene, betaµg159
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU266
Lycopeneµg0
Lutein + zeaxanthinµg1160
Vitamin E (alpha-tocopherol)mg2.17
Vitamin E, addedmg0
Tocopherol, betamg0.13
Tocopherol, gammamg23.42
Tocopherol, deltamg0.55
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg13.2
Lipids
Fatty acids, total saturatedg5.645
04:00:00g0
06:00:00g0
8:0g0
10:0g0
12:0g0
13:0g0
14:0g0.012
15:0g0
16:0g4.994
17:0g0.011
18:0g0.558
20:0g0.033
22:0g0.026
24:0g0.011
Fatty acids, total monounsaturatedg24.534
14:1g0.005
15:1g0.009
16:1 undifferentiatedg0.464
17:1g0.02
18:1 undifferentiatedg23.926
18:1 tg0
20:1g0.106
22:1 undifferentiatedg0.005
24:1 cg0
Fatty acids, total polyunsaturatedg13.346
18:2 undifferentiatedg13.125
18:2 n-6 c,cg13.125
18:2 t not further definedg0
18:3 undifferentiatedg0.212
18:3 n-3 c,c,c (ALA)g0.212
18:3 n-6 c,c,cg0
18:04:00g0
20:2 n-6 c,cg0
20:3 undifferentiatedg0.005
20:4 undifferentiatedg0.005
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Fatty acids, total transg0
Fatty acids, total trans-monoenoicg0
Cholesterolmg0
Stigmasterolmg2
Campesterolmg10
Beta-sitosterolmg210
Amino Acids
Tryptophang0.262
Threonineg0.714
Isoleucineg0.957
Leucineg1.675
Lysineg1.189
Methionineg0.375
Cystineg0.305
Phenylalanineg1.14
Tyrosineg0.531
Valineg1.305
Arginineg2.228
Histidineg0.535
Alanineg1.016
Aspartic acidg1.968
Glutamic acidg4.49
Glycineg1.054
Prolineg0.98
Serineg1.34
Hydroxyprolineg0.096
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
[Source: United States Department of Agriculture Agricultural Research Service 11]

Table 3. Pistachio nuts nutritional value compared with other nuts

Pistachio nuts nutritional value compared with other nuts

[Source: 12]

Health benefits of pistachio nuts

Pistachio nuts are considered a rich source of many important bio-functional compounds that are useful for the human diet and known for their various pharmacological properties such as antimicrobial, anti-inflammatory, insecticidal, and anti-nociceptive activities 13. Recently, scientists analyzed and described the nutraceutical, antioxidant, and cytoprotective activity of crude phenols and anthocyanins-rich extracts derived from ripe pistachio hulls, a by-product of the pistachio industry 14. As their nutritional profile suggests, pistachios can play an important role in improving such metabolic conditions as overweight, type 2 diabetes mellitus or metabolic syndrome.

Nut consumption is associated with significant reductions in cardiovascular disease risk and all-cause mortality 15. In the Nurses’ Health Study 15, women who consumed >2 servings of nuts per week had an 18% reduction in cardiac death compared with women who did not eat nuts regularly. In short-term, randomized trials, almonds, walnuts and pistachios 16 significantly reduced low-density lipoprotein (LDL) “bad” cholesterol and total cholesterol, when compared with a typical Western diet or diets low in saturated fat 17. Scientists have shown previously that including 1 or 2 servings per day of pistachios in a healthy diet reduced LDL “bad” cholesterol by 9% to 12% 18. The effects of pistachios on the ratio of LDL “bad” cholesterol to high-density lipoprotein “good” (HDL) cholesterol were dose dependent, with larger improvements in LDL “bad” cholesterol/high-density lipoprotein “good” cholesterol 18 and greater reductions in oxidized LDL “bad” cholesterol 19 when participants consumed 2 servings per day. Relative to other nuts, pistachios are a rich source of antioxidants, including lutein, β-carotene, and γ-tocopherol in addition to containing selenium, flavonoids, and proanthocyanidins 20. As would be expected, pistachios have a relatively high in vitro antioxidant capacity 21. Oxidized LDL “bad” cholesterol 22 and lipid peroxidation products are found in elevated concentrations in atherosclerotic plaques 23 and are thought to play an important role in the development and progression of atherosclerosis 22. Thus, strategies that reduce in body oxidative stress are thought to confer cardioprotective effects.

Lipid Profile

Previous dietary interventions with pistachios conducted in humans have shown improvements in lipoprotein profiles 24 and one reported a beneficial effect on serum antioxidant status (measured using a malondialdehyde assay) in 44 males and females who consumed a diet that provided 20% of their energy as pistachios for 3 weeks 24. Another study 25 demonstrated beneficial effects of pistachios on multiple biomarkers of oxidative state. The study found significant decreases in serum oxidized-LDL “bad” cholesterol in participants following the pistachio-enriched diets relative to the control diet 25. The decrease in oxidized-LDL “bad” cholesterol was accompanied by a significant increase in serum concentrations of antioxidants (relative to the control diet), including γ-tocopherol, lutein and β-carotene, thus indicating a beneficial effect of pistachios on concentrations of serum antioxidants 25. The results of this 2016 systematic review 26 provide solid evidence that intake of pistachio nuts may exerts favorable effects on the traditional blood profile, provided that their consumption does not increase the habitual or recommended daily caloric intake.

In summary, evidence suggests that pistachios may improve well-established and novel blood lipid markers of atherosclerosis and therefore help decrease cardiovascular risk. In order to fully establish the potential health effects of pistachio consumption on the prevention of cardiovascular events clinical trials needed to be carried out in the future.

Figure 3. Possible health benefits of pistachios consumption

health benefits of pistachio nuts

Note: CVD = cardiovascular disease

[Source 27]

Lowers Blood Pressure

Several prospective studies have shown an inverse association between nut consumption and blood pressure or hypertension 12. However, the results of clinical trials are more controversial. The intake of 10% of energy in the form of pistachios for 1 month significantly reduced systolic blood pressure and made no difference in diastolic blood pressure compared with the control nut-free group 28. Similarly, a recent study conducted in type 2 diabetes mellitus subjects showed a reduction in systolic blood pressure after 4 weeks consuming a diet with 20% energy from pistachios 29. Moreover, a recent systematic review and meta-analysis of more than 20 randomized controlled trials found that although diastolic blood pressure was reduced by the intake of mixed nuts, pistachios alone seemed to have the strongest effect on reducing both systolic blood pressure and diastolic blood pressure 30.

Walnut, hazelnut, and pistachio consumption also improves the circulating concentrations of endothelial markers and endothelial function 30.

In conclusion, chronic pistachio consumption has proved to have a beneficial effect on blood pressure and endothelial function, which may help to improve cardiovascular risk 12.

Glucose and Insulin Metabolism

Pistachios have more total carbohydrates (29% w/w) than do other nuts, but their consumption has no deleterious effect in subjects with abnormal glucose and insulin metabolism.

Data from several epidemiological studies and clinical trials suggest that the frequency of nut consumption is inversely related to an increased risk of type 2 diabetes mellitus. This may be because of the fact that nuts are relatively high in fiber, healthy fats, antioxidants, and anti-inflammatory content 31. In addition, among all nuts, pistachios have a low glycemic index (GI), suggesting that they may reduce postprandial glycemia and insulinemia and therefore contribute to reducing the type 2 diabetes mellitus risk 32. Pistachios consumed alone had a minimal effect on postprandial glycemia, but the addition of pistachios to a meal containing foods rich in carbohydrates with a high glycemic index (eg, pasta, parboiled rice, or instant mashed potatoes) 33 or bread 32 reduces postprandial glycemia in a dose-dependent response.

Several clinical studies have investigated the effect of pistachio consumption on glucose concentrations. They observed a significant decrease in fasting plasma glucose 34, in glucose but not in insulin blood levels 35, and in both fasting plasma glucose and insulin levels 36 after pistachio intake. Only 1 cross-over study conducted on metabolic syndrome subjects free of type 2 diabetes has shown no significant changes in fasting plasma glucose or in insulin concentrations during the pistachio-enriched diet period compared with the intervention period without pistachios 37.

Pistachio consumption has also proved to have beneficial effects on diabetes control. In a randomized controlled study 38, the intake of mixed nuts (including pistachios) for 3 months in type 2 diabetes mellitus subjects, as a replacement for carbohydrate-containing foods, demonstrated for the first time a significant decrease in hemoglobin A1c in a full-nut dose compared with a half-nut and control-muffin doses. Results were similar in a recent crossover trial with 48 diabetic participants after 3 months of pistachio consumption 39. Pistachio intake has also recently been found to significantly enhance the glucose and insulin metabolism of prediabetic patients 36 and improve insulin resistance status and other cardiovascular risk factors.

Despite the positive results observed for glucose metabolism, more studies need to be made to evaluate the long-term effects of pistachio consumption on insulin resistance and type 2 diabetes mellitus prevention and control.

Satiety Regulation and Weight Management

Because nuts are energy-dense foods with a high fat content, one of the main concerns regarding the regular consumption of nuts in a worldwide pandemic of overweight and obesity is that nuts are believed to be fattening. To date, however, epidemiological studies have failed to find any association between nut or pistachio consumption and either weight gain or an increased risk of obesity 40. Likewise, controlled feeding trials confirm that adding nuts to usual diets does not induce weight gain 41. Several studies that have evaluated pistachios’ effect on body weight as a secondary outcome have reiterated their null effect on body weight and body mass index 42. Only one recent study conducted in type 2 diabetes mellitus subjects has found a significant reduction of body mass index after pistachio consumption 35.

These findings may be explained by the energy density of pistachios; their content in fiber, protein, and unsaturated fatty acids; and their crunchy physical structure, which may induce satiety and therefore reduce subsequent food intake 43. It has been speculated that various signaling systems (ie, mechanical, nutrient, and sensory) are activated by mastication, which may modify appetitive sensations 44. To date, only 2 studies have evaluated the satiating properties of pistachio nuts in humans. The conclusions are that the consumption of in-shell pistachios led to lower calorie intake than the consumption of kernels 45 and that the visual cue of empty pistachio shells helped the participants to consume fewer calories during the day 46.

In addition, the monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) that nuts contain have a greater thermic effect that will induce higher thermogenic effect 47 than saturated fatty acids, which can lead to less fat accumulation by an increase in sympathetic activity in brown adipose tissue 48. Finally, after nut intake, fat is malabsorbed to a slight extent largely because the fat in the walls of nut cells is not completely digested in the gut 49, suggesting that energy from nuts is poorly absorbed. Therefore, the metabolized energy contained in these types of nut is less than predicted by the Atwater general factors, which is the system used for the calculation of the available energy of foods developed from experimental studies in the early years of the 20th century 50.

Traditional medicine uses

In traditional Iranian medicine, different parts of pistachio have been used for a long time as useful remedies for different diseases, for example, the fruit kernel of pistachio as a cardiac, stomach, hepatic, and brain tonic 51.

Table 4. Traditional medical uses of pistachio (Pistacia vera L.)

Pistacia vera IranNut shellTonic, sedative, and antidiarrhea52
FruitFood53
JordanOilFacial skin cleanser54
TurkeyResinAsthma, stomach ache, and hemorrhoids55
[Source 51]

New trends in pistachio research

Pistachio in the prevention of type 2 diabetes mellitus and other Metabolic Diseases

Research has focused widely on the beneficial effects of pistachios on such conditions as type 2 diabetes mellitus and metabolic syndrome 56. However, very little information is currently available on the potential role pistachio nuts play in preventing the development of chronic diseases such as type 2 diabetes mellitus.

Pistachios in cancer or neurodegenerative diseases

Vitamin E and other antioxidants provide some protection against certain forms of cancer. Therefore, foods such as pistachios, with a high content of γ-tocopherol (a form of vitamin E) and other antioxidants may reduce the risk of different types of cancer 57. Moreover, the skin of nuts contains considerable amounts of resveratrol 58, which has been widely studied for its role in cancer, but new research is now changing this focus to other diseases such as Alzheimer’s or Parkinson’s disease 59.

Pistachio and gut microbiota

Recent findings have shown that both pistachios and almonds have a potential prebiotic effect in healthy populations, and that the effect of the former is greater 60. Thereby, pistachios’ microbiota modulation increased the number of butyrate-producing bacteria, identified as potentially beneficial, whereas bifidobacteria was not affected. However, new investigations should be performed to contrast and further explore these findings. Regulation of the phyla composition or the production of regulatory and protective molecules (eg, butyrate) by our gut microbiota could be mediators of the well-established beneficial properties of pistachios and other nuts.

  1. Smeriglio A, Denaro M, Barreca D, et al. In Vitro Evaluation of the Antioxidant, Cytoprotective, and Antimicrobial Properties of Essential Oil from Pistacia vera L. Variety Bronte Hull. Morikawa T, ed. International Journal of Molecular Sciences. 2017;18(6):1212. doi:10.3390/ijms18061212. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486035/[]
  2. Kashaninejad M, Mortazavi A, Safekordi A, Tabil LG. Some physical properties of Pistachio (Pistacia vera L.) nut and its kernel. Journal of Food Engineering. 2006;72(1):30–38[]
  3. Five Pistacia species (P. vera, P. atlantica, P. terebinthus, P. khinjuk, and P. lentiscus): a review of their traditional uses, phytochemistry, and pharmacology. Bozorgi M, Memariani Z, Mobli M, Salehi Surmaghi MH, Shams-Ardekani MR, Rahimi R. ScientificWorldJournal. 2013; 2013():219815. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876903/[]
  4. derMarderosian A, Beutler JA. The Review of Natural Products. 6th edition. Missouri, Mo, USA: Wolters Kluwer Health; 2010[]
  5. In vitro antioxidant and in vivo photoprotective effect of pistachio (Pistacia vera L., variety Bronte) seed and skin extracts. Martorana M, Arcoraci T, Rizza L, Cristani M, Bonina FP, Saija A, Trombetta D, Tomaino A. Fitoterapia. 2013 Mar; 85:41-8. https://www.sciencedirect.com/science/article/pii/S0367326X13000026[]
  6. Pistachio nut allergy: An updated overview. Crit Rev Food Sci Nutr. 2017 Sep 19:1-17. doi: 10.1080/10408398.2017.1379947[]
  7. Hajiboland R, Norouzi F, Poschenrieder C. Growth, physiological, biochemical and ionic responses of pistachio seedlings to mild and high salinity. Trees. 2014;28(4):1065–1078. doi: 10.1007/s00468-014-1018-x[]
  8. Sathe SK, Monaghan EK, Kshiesagar HH, Venkatachalam M. Chemical composition of edible nut seeds and its implications in human health. In: Alsalvar C, Shahidi F, editors. , ed. Tree Nuts Composition, Phytochemicals and Health Effects. Boca Raton, FL: CRC Press Taylor Francis; 2009:12–29.[]
  9. Concentrations of proanthocyanidins in common foods and estimations of normal consumption. Gu L, Kelm MA, Hammerstone JF, Beecher G, Holden J, Haytowitz D, Gebhardt S, Prior RL. J Nutr. 2004 Mar; 134(3):613-7. https://www.ncbi.nlm.nih.gov/pubmed/14988456/[]
  10. Ros E. Health Benefits of Nut Consumption. Nutrients. 2010;2(7):652-682. doi:10.3390/nu2070652. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257681/[]
  11. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][]
  12. Hernández-Alonso P, Bulló M, Salas-Salvadó J. Pistachios for Health: What Do We Know About This Multifaceted Nut? Nutrition Today. 2016;51(3):133-138. doi:10.1097/NT.0000000000000160. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890834/[][][]
  13. Evaluation of the nutraceutical, antioxidant and cytoprotective properties of ripe pistachio (Pistacia vera L., variety Bronte) hulls. Barreca D, Laganà G, Leuzzi U, Smeriglio A, Trombetta D, Bellocco E. Food Chem. 2016 Apr 1; 196():493-502. https://www.sciencedirect.com/science/article/pii/S030881461501420X[]
  14. Bellocco E., Barreca D., Laganà G., Calderaro A., El Lekhlifi Z., Chebaibi S., Smeriglio A., Trombetta D. Cyanidin-3-O-galactoside in ripe pistachio (Pistachia vera L. variety Bronte) hulls: Identification and evaluation of its antioxidant and cytoprotective activities. J. Funct. Foods. 2016;27:376–385. doi: 10.1016/j.jff.2016.09.016[]
  15. Baer HJ, Glynn RJ, Hu FB, Hankinson SE, Willett WC, Colditz GA, Stampfer M, Rosner B. Risk factors for mortality in the Nurses’ Health Study: a competing risks analysis. Am J Epidemiol. 2010;173:319–329 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105270/[][]
  16. Gebauer SK, West SG, Kay CD, Alaupovic P, Bagshaw D, Kris-Etherton PM. Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study. Am J Clin Nutr. 2008;88:651–659 https://www.ncbi.nlm.nih.gov/pubmed/18779280[]
  17. Sabate J, Oda K, Ros E. Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials. Arch Intern Med. 2010;170:821–827 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/415912[]
  18. Gebauer SK, West SG, Kay CD, Alaupovic P, Bagshaw D, Kris-Etherton PM. Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study. Am J Clin Nutr. 2008;88:651–659. https://www.ncbi.nlm.nih.gov/pubmed/18779280[][]
  19. Kay CD, Gebauer SK, West SG, Kris-Etherton PM. Pistachios increase serum antioxidants and lower serum oxidized-ldl in hypercholesterolemic adults. J Nutr. 2010;140:1093–1098. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140215/[]
  20. Concentrations of proanthocyanidins in common foods and estimations of normal consumption. Gu L, Kelm MA, Hammerstone JF, Beecher G, Holden J, Haytowitz D, Gebhardt S, Prior RL. J Nutr. 2004 Mar; 134(3):613-7. https://academic.oup.com/jn/article/134/3/613/4688609[]
  21. Antioxidant activity of Sicilian pistachio (Pistacia vera L. var. Bronte) nut extract and its bioactive components. Gentile C, Tesoriere L, Butera D, Fazzari M, Monastero M, Allegra M, Livrea MA. J Agric Food Chem. 2007 Feb 7; 55(3):643-8. https://www.ncbi.nlm.nih.gov/pubmed/17263455/[]
  22. Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease. Toshima S, Hasegawa A, Kurabayashi M, Itabe H, Takano T, Sugano J, Shimamura K, Kimura J, Michishita I, Suzuki T, Nagai R. Arterioscler Thromb Vasc Biol. 2000 Oct; 20(10):2243-7. http://atvb.ahajournals.org/content/20/10/2243.long[][]
  23. Postprandial lipid oxidation and cardiovascular disease risk. Bowen PE, Borthakur G. Curr Atheroscler Rep. 2004 Nov; 6(6):477-84. https://www.ncbi.nlm.nih.gov/pubmed/15485594/[]
  24. Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers. Kocyigit A, Koylu AA, Keles H. Nutr Metab Cardiovasc Dis. 2006 Apr; 16(3):202-9. https://www.ncbi.nlm.nih.gov/pubmed/16580587/[][]
  25. Kay CD, Gebauer SK, West SG, Kris-Etherton PM. Pistachios Increase Serum Antioxidants and Lower Serum Oxidized-LDL in Hypercholesterolemic Adults. The Journal of Nutrition. 2010;140(6):1093-1098. doi:10.3945/jn.109.117366. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140215/[][][]
  26. More pistachio nuts for improving the blood lipid profile. Systematic review of epidemiological evidence. Acta Biomed. 2016 May 6;87(1):5-12. https://www.ncbi.nlm.nih.gov/pubmed/27163889[]
  27. Health benefits of pistachios consumption, Natural Product Research, Received 17 Aug 2017, Accepted 17 Nov 2017, Published online: 15 Dec 2017. DOI: 10.1080/14786419.2017.1408093[]
  28. West SG, Gebauer SK, Kay CD, et al. Diets containing pistachios reduce systolic blood pressure and peripheral vascular responses to stress in adults with dyslipidemia. Hypertension. 2012;60(1):58–63. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862178/[]
  29. Sauder KA, McCrea CE, Ulbrecht JS, Kris-Etherton PM, West SG. Pistachio nut consumption modifies systemic hemodynamics, increases heart rate variability, and reduces ambulatory blood pressure in well-controlled type 2 diabetes: a randomized trial. J Am Heart Assoc. 2014;3(4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310367/[]
  30. Mohammadifard N, Salehi-Abargouei A, Salas-Salvadó J, Guasch-Ferré M, Humphries K, Sarrafzadegan N. The effect of tree nut, peanut, and soy nut consumption on blood pressure: a systematic review and meta-analysis of randomized controlled clinical trials. Am J Clin Nutr. 2015;101(5):966–982. https://www.ncbi.nlm.nih.gov/pubmed/25809855[][]
  31. Ros E. Health benefits of nut consumption. Nutrients. 2010;2(7):652–682. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257681/[]
  32. Kendall CW, West SG, Augustin LS, et al. Acute effects of pistachio consumption on glucose and insulin, satiety hormones and endothelial function in the metabolic syndrome. Eur J Clin Nutr. 2014;68(3):370–375. https://www.ncbi.nlm.nih.gov/pubmed/24424074[][]
  33. Kendall CW, Josse AR, Esfahani A, Jenkins DJ. The impact of pistachio intake alone or in combination with high-carbohydrate foods on post-prandial glycemia. Eur J Clin Nutr. 2011;65(6):696–702 https://www.ncbi.nlm.nih.gov/pubmed/21364607[]
  34. Sari I, Baltaci Y, Bagci C, et al. Effect of pistachio diet on lipid parameters, endothelial function, inflammation, and oxidative status: a prospective study. Nutrition. 2010;26(4):399–404 https://www.ncbi.nlm.nih.gov/pubmed/19647416[]
  35. Parham M, Heidari S, Khorramirad A, et al. Effects of pistachio nut supplementation on blood glucose in patients with type 2 diabetes: a randomized crossover trial. Rev Diabet Stud. 2014;11(2):190–196. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310069/[][]
  36. Hernández-Alonso P, Salas-Salvadó J, Baldrich-Mora M, Juanola-Falgarona M, Bulló M. Beneficial effect of pistachio consumption on glucose metabolism, insulin resistance, inflammation, and related metabolic risk markers: a randomized clinical trial. Diabetes Care. 2014;37(11):3098–3105 https://www.ncbi.nlm.nih.gov/pubmed/25125505[][]
  37. Wang X, Li Z, Liu Y, Lv X, Yang W. Effects of pistachios on body weight in Chinese subjects with metabolic syndrome. Nutr J. 2012;11:20. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383470/[]
  38. Jenkins DJA, Kendall CWC, Banach MS, et al. Statement of Retraction. Nuts as a Replacement for Carbohydrates in the Diabetic Diet. Diabetes Care 2011;34:Diabetes Care. 34:1706.. DOI: 10.2337/dc11-0338. Diabetes Care. 2016;39(2):319. doi:10.2337/dc16-rt02.[]
  39. Parham M, Heidari S, Khorramirad A, et al. Effects of pistachio nut supplementation on blood glucose in patients with type 2 diabetes: a randomized crossover trial. Rev Diabet Stud. 2014;11(2):190–196 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310069/[]
  40. Casas-Agustench P, Bulló M, Ros E, Basora J, Salas-Salvadó J; Nureta-PREDIMED Investigators. Cross-sectional association of nut intake with adiposity in a Mediterranean population. Nutr Metab Cardiovasc Dis. 2011;21(7):518–525 https://www.ncbi.nlm.nih.gov/pubmed/20219336[]
  41. Gulati S, Misra A, Pandey RM, Bhatt SP, Saluja S. Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: a 24-wk, randomized control trial. Nutrition. 2014;30(2):192–197 https://www.ncbi.nlm.nih.gov/pubmed/24377454[]
  42. Gebauer SK, West SG, Kay CD, Alaupovic P, Bagshaw D, Kris-Etherton PM. Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study. Am J Clin Nutr. 2008;88(3):651–659 https://www.ncbi.nlm.nih.gov/pubmed/18779280[]
  43. Tan SY, Dhillon J, Mattes RD. A review of the effects of nuts on appetite, food intake, metabolism, and body weight. Am J Clin Nutr. 2014;100(suppl 1):412S–422S https://www.ncbi.nlm.nih.gov/pubmed/24920033[]
  44. Cassady BA, Hollis JH, Fulford AD, Considine RV, Mattes RD. Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response. Am J Clin Nutr. 2009;89(3):794–800[]
  45. Honselman CS, Painter JE, Kennedy-Hagan KJ, et al. In-shell pistachio nuts reduce caloric intake compared to shelled nuts. Appetite. 2011;57(2):414–417 https://www.ncbi.nlm.nih.gov/pubmed/21645565[]
  46. Kennedy-Hagan K, Painter JE, Honselman C, Halvorson A, Rhodes K, Skwir K. The effect of pistachio shells as a visual cue in reducing caloric consumption. Appetite. 2011;57(2):418–420 https://www.ncbi.nlm.nih.gov/pubmed/21704666[]
  47. Alper CM, Mattes RD. Effects of chronic peanut consumption on energy balance and hedonics. Int J Obes Relat Metab Disord. 2002;26(8):1129–1137 https://www.ncbi.nlm.nih.gov/pubmed/12119580[]
  48. Takeuchi H, Matsuo T, Tokuyama K, Shimomura Y, Suzuki M. Diet-induced thermogenesis is lower in rats fed a lard diet than in those fed a high oleic acid safflower oil diet, a safflower oil diet or a linseed oil diet. J Nutr. 1995;125(4):920–925 https://www.ncbi.nlm.nih.gov/pubmed/7722695[]
  49. Ellis PR, Kendall CW, Ren Y, et al. Role of cell walls in the bioaccessibility of lipids in almond seeds. Am J Clin Nutr. 2004;80(3):604–613. https://www.ncbi.nlm.nih.gov/pubmed/15321799[]
  50. Baer DJ, Gebauer SK, Novotny JA. Measured energy value of pistachios in the human diet. Br J Nutr. 2012;107(1):120–125. https://www.ncbi.nlm.nih.gov/pubmed/21733319[]
  51. Bozorgi M, Memariani Z, Mobli M, Salehi Surmaghi MH, Shams-Ardekani MR, Rahimi R. Five Pistacia species (P. vera, P. atlantica, P. terebinthus, P. khinjuk, and P. lentiscus): A Review of Their Traditional Uses, Phytochemistry, and Pharmacology. The Scientific World Journal. 2013;2013:219815. doi:10.1155/2013/219815. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876903/[][]
  52. Aghili MH. Makhzan-al-Advia. Tehran, Iran: Tehran University of Medical Sciences; 2009. Edited by R. Rahimi, M.R. Shams Ardekani and F. Farjadmand.[]
  53. Kashaninejad M, Mortazavi A, Safekordi A, Tabil LG. Some physical properties of Pistachio (Pistacia vera L.) nut and its kernel. Journal of Food Engineering. 2006;72(1):30–38.[]
  54. Lev E, Amar Z. Ethnopharmacological survey of traditional drugs sold in the Kingdom of Jordan. Journal of Ethnopharmacology. 2002;82(2-3):131–145[]
  55. Orhan I, Küpeli E, Aslan M, Kartal M, Yesilada E. Bioassay-guided evaluation of anti-inflammatory and antinociceptive activities of pistachio, Pistacia vera L. . Journal of Ethnopharmacology. 2006;105(1-2):235–240[]
  56. Gulati S, Misra A, Pandey RM, Bhatt SP, Saluja S. Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: a 24-wk, randomized control trial. Nutrition. 2014;30(2):192–197. https://www.ncbi.nlm.nih.gov/pubmed/24377454[]
  57. Yang CS, Suh N, Kong AN. Does vitamin E prevent or promote cancer? Cancer Prev Res (Phila). 2012;5(5):701–705. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502042/[]
  58. Tokuşoglu O, Unal MK, Yemiş F. Determination of the phytoalexin resveratrol (3,5,4’-trihydroxystilbene) in peanuts and pistachios by high-performance liquid chromatographic diode array (HPLC-DAD) and gas chromatography-mass spectrometry (GC-MS). J Agric Food Chem. 2005;53(12):5003–5009 https://www.ncbi.nlm.nih.gov/pubmed/15941348[]
  59. Bastianetto S, Ménard C, Quirion R. Neuroprotective action of resveratrol. Biochim Biophys Acta. 2015;1852(6):1195–1201. https://www.ncbi.nlm.nih.gov/pubmed/25281824[]
  60. Ukhanova M, Wang X, Baer DJ, Novotny JA, Fredborg M, Mai V. Effects of almond and pistachio consumption on gut microbiota composition in a randomised cross-over human feeding study. Br J Nutr. 2014;111(12):2146–2152 https://www.ncbi.nlm.nih.gov/pubmed/24642201[]
read more

Is granola good for you

Granola

What is granola

Granola is a cereal-like breakfast food and snack food consisting of rolled oats, nuts, honey or other sweeteners such as brown sugar, and sometimes puffed rice, that is usually baked until it is crisp, toasted and golden brown. During the baking process, the mixture is stirred to maintain a loose breakfast cereal consistency. Dried fruits, such as raisins and dates, and confections such as chocolate are sometimes added. Granola breakfast cereal, particularly if it includes flax seeds, is often used to improve digestion. Granola breakfast cereal is often eaten in combination with yogurt, honey, fresh fruit (such as bananas, strawberries or blueberries), milk or other forms of cereal. It also serves as a topping for various pastries, desserts or ice cream. Though granola is a good source of protein and fiber, granola can also be high in sugar, fat and calories, especially the store-bought varieties. It’s best to watch your portion sizes or create your own healthier granola to limit the amount of fat, calories and sugar in each serving.

How many calories should breakfast provide ?

A helpful rule of thumb to maintain a healthy weight is to follow the 400-600-600 kcal approach.

That means having about:

  • 400kcal for breakfast (including any drinks and accompaniments)
  • 600kcal for lunch (including any drinks and accompaniments)
  • 600kcal for dinner (including any drinks and accompaniments)

That leaves you with just enough left over to enjoy a few healthy drinks and snacks throughout the day. This advice is based on a adult’s daily recommended calorie intake of 2,000kcal.

You might get about 150kcal from a 35g serving of granola (approx. only depending on make and brands). You could add a medium sliced banana and 200ml of semi-skimmed milk, which altogether would provide about 350kcals.

You need fuel in the morning, and starting the day with a filling breakfast can help you avoid reaching for a less healthy mid-morning snack to keep you going until lunch.

Granola nutrition

Granola calories depends on the added sugar and fat content of the granola breakfast cereal.

Table 1. Granola nutrition facts

NutrientUnitValue per 100 g
Approximates
Energykcal418
Proteing10.91
Total lipid (fat)g14.55
Carbohydrate, by differenceg63.64
Fiber, total dietaryg5.5
Sugars, totalg23.64
Minerals
Calcium, Camg73
Iron, Femg2.86
Sodium, Namg227
Vitamins
Vitamin C, total ascorbic acidmg0
Vitamin A, IUIU0
Lipids
Fatty acids, total saturatedg0
Fatty acids, total transg0
Cholesterolmg0

Ingredients: Oats, Maple syrup, Brown sugar, Canola oil, Vanilla, Sea salt, Cinnamon.
Manufacturer: Good Life

[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 2. Granola nutrition facts

NutrientUnitcup 55 g Value per 100 g
Approximates
Energykcal240436
Proteing610.91
Total lipid (fat)g712.73
Carbohydrate, by differenceg3970.91
Fiber, total dietaryg47.3
Sugars, totalg1221.82
Minerals
Calcium, Camg2036
Iron, Femg1.312.38
Potassium, Kmg140255
Sodium, Namg70127
Vitamins
Vitamin C, total ascorbic acidmg00
Vitamin A, IUIU00
Lipids
Fatty acids, total saturatedg1.0011.82
Fatty acids, total monounsaturatedg3.4986.36
Fatty acids, total polyunsaturatedg2.5024.55
Fatty acids, total transg00
Cholesterolmg00

Ingredients: Whole grain rolled oats, cane sugar, canola oil, rice flour, flax seed, honey, flax seed meal, freeze dried blueberries, salt, natural flavor, barley malt syrup, mixed tocopherols (to maintain freshness).
Manufacturer: Post

[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 3. Granola bars (plain and hard) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg3.9
Energykcal471
EnergykJ1972
Proteing10.1
Total lipid (fat)g19.8
Ashg1.9
Carbohydrate, by differenceg64.4
Fiber, total dietaryg5.3
Sugars, totalg28.57
Minerals
Calcium, Camg61
Iron, Femg2.95
Magnesium, Mgmg97
Phosphorus, Pmg277
Potassium, Kmg336
Sodium, Namg294
Zinc, Znmg2.03
Copper, Cumg0.392
Manganese, Mnmg1.777
Selenium, Seµg16.2
Vitamins
Vitamin C, total ascorbic acidmg0.9
Thiaminmg0.264
Riboflavinmg0.119
Niacinmg1.581
Pantothenic acidmg0.813
Vitamin B-6mg0.085
Folate, totalµg23
Folic acidµg0
Folate, foodµg23
Folate, DFEµg23
Choline, totalmg22
Betainemg6.9
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg2
Retinolµg0
Carotene, betaµg17
Carotene, alphaµg6
Cryptoxanthin, betaµg0
Vitamin A, IUIU33
Lycopeneµg0
Lutein + zeaxanthinµg189
Vitamin E (alpha-tocopherol)mg2.09
Vitamin E, addedmg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg14.6
Lipids
Fatty acids, total saturatedg2.37
04:00:00g0
06:00:00g0
08:00:00g0
10:00:00g0
12:00:00g0.01
14:00:00g0.01
16:00:00g1.54
18:00:00g0.76
Fatty acids, total monounsaturatedg4.38
16:1 undifferentiatedg0.01
18:1 undifferentiatedg4.37
20:01:00g0.13
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg12.05
18:2 undifferentiatedg11.99
18:3 undifferentiatedg0.06
18:04:00g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Cholesterolmg0
Amino Acids
Tryptophang0.177
Threonineg0.264
Isoleucineg0.352
Leucineg0.724
Lysineg0.4
Methionineg0.177
Cystineg0.304
Phenylalanineg0.479
Tyrosineg0.352
Valineg0.508
Arginineg0.674
Histidineg0.216
Alanineg0.46
Aspartic acidg0.83
Glutamic acidg1.975
Glycineg0.499
Prolineg0.518
Serineg0.47
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
Isoflavones
Daidzeinmg0.05
Genisteinmg0.07
Total isoflavonesmg0.13
Biochanin Amg0
Formononetinmg0
Coumestrolmg0.01
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 4. Granola bars (plain and soft and uncoated) nutrition facts

NutrientUnitValue per 100 gbar (1 oz) 28 g
Approximates
Waterg6.41.79
Energykcal443124
Proteing7.42.07
Total lipid (fat)g17.24.82
Carbohydrate, by differenceg67.318.84
Fiber, total dietaryg4.61.3
Minerals
Calcium, Camg10529
Iron, Femg2.560.72
Magnesium, Mgmg7421
Phosphorus, Pmg23064
Potassium, Kmg32591
Sodium, Namg27878
Zinc, Znmg1.50.42
Vitamins
Vitamin C, total ascorbic acidmg00
Thiaminmg0.2950.083
Riboflavinmg0.1650.046
Niacinmg0.5150.144
Vitamin B-6mg0.10.028
Folate, DFEµg247
Vitamin B-12µg0.390.11
Vitamin A, RAEµg00
Vitamin A, IUIU00
Lipids
Fatty acids, total saturatedg7.252.03
Fatty acids, total monounsaturatedg3.821.07
Fatty acids, total polyunsaturatedg5.321.49
Cholesterolmg00
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 5. Granola bars (soft, uncoated and raisin) nutrition facts

NutrientUnitValue per 100 gbar (1.5 oz) 43 g bar (1 oz) 28 g
Approximates
Waterg6.42.751.79
Energykcal448193125
Proteing7.63.272.13
Total lipid (fat)g17.87.654.98
Carbohydrate, by differenceg66.428.5518.59
Fiber, total dietaryg4.21.81.2
Minerals
Calcium, Camg1014328
Iron, Femg2.441.050.68
Magnesium, Mgmg723120
Phosphorus, Pmg2209562
Potassium, Kmg362156101
Sodium, Namg28212179
Zinc, Znmg1.30.560.36
Vitamins
Vitamin C, total ascorbic acidmg000
Thiaminmg0.2310.0990.065
Riboflavinmg0.1630.070.046
Niacinmg1.1010.4730.308
Vitamin B-6mg0.1030.0440.029
Folate, DFEµg2196
Vitamin B-12µg0.180.080.05
Vitamin A, RAEµg000
Vitamin A, IUIU000
Lipids
Fatty acids, total saturatedg9.574.1152.68
Fatty acids, total monounsaturatedg2.841.2210.795
Fatty acids, total polyunsaturatedg3.211.380.899
Cholesterolmg000
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 6. Granola bars (hard and chocolate chip) nutrition facts

NutrientUnitValue per 100 goz 28.35 g bar 24 g
Approximates
Waterg2.40.680.58
Energykcal438124105
Proteing7.32.071.75
Total lipid (fat)g16.34.623.91
Carbohydrate, by differenceg72.120.4417.3
Fiber, total dietaryg4.41.21.1
Minerals
Calcium, Camg772218
Iron, Femg3.050.860.73
Magnesium, Mgmg722017
Phosphorus, Pmg2045849
Potassium, Kmg2517160
Sodium, Namg3449883
Zinc, Znmg1.930.550.46
Vitamins
Vitamin C, total ascorbic acidmg0.100
Thiaminmg0.180.0510.043
Riboflavinmg0.10.0280.024
Niacinmg0.5550.1570.133
Vitamin B-6mg0.0580.0160.014
Folate, DFEµg1343
Vitamin B-12µg0.0100
Vitamin A, RAEµg210
Vitamin A, IUIU421210
Lipids
Fatty acids, total saturatedg11.413.2352.738
Fatty acids, total monounsaturatedg2.630.7460.631
Fatty acids, total polyunsaturatedg1.270.360.305
Cholesterolmg000
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 7. Granola bars (hard and almond) nutrition facts

NutrientUnitValue per 100 goz 28.35 g bar 24 g
Approximates
Waterg3.10.880.74
Energykcal495140119
Proteing7.72.181.85
Total lipid (fat)g25.57.236.12
Carbohydrate, by differenceg6217.5814.88
Fiber, total dietaryg4.81.41.2
Minerals
Calcium, Camg3298
Iron, Femg2.50.710.6
Magnesium, Mgmg812319
Phosphorus, Pmg2286555
Potassium, Kmg2737766
Sodium, Namg2567361
Zinc, Znmg1.580.450.38
Vitamins
Vitamin C, total ascorbic acidmg000
Thiaminmg0.280.0790.067
Riboflavinmg0.070.020.017
Niacinmg0.610.1730.146
Vitamin B-6mg0.0470.0130.011
Folate, DFEµg1233
Vitamin B-12µg000
Vitamin A, RAEµg210
Vitamin A, IUIU37109
Lipids
Fatty acids, total saturatedg12.513.5473.002
Fatty acids, total monounsaturatedg7.742.1941.858
Fatty acids, total polyunsaturatedg3.761.0660.902
Cholesterolmg000
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 8. Granola bars (non-fat and fruit filled) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg13.7
Energykcal342
Proteing5.9
Total lipid (fat)g0.9
Carbohydrate, by differenceg77.6
Fiber, total dietaryg7.4
Sugars, totalg45.24
Minerals
Calcium, Camg3
Iron, Femg4
Magnesium, Mgmg50
Phosphorus, Pmg122
Potassium, Kmg220
Sodium, Namg16
Zinc, Znmg1.42
Vitamins
Vitamin C, total ascorbic acidmg1.7
Thiaminmg0.03
Riboflavinmg0.07
Niacinmg0.4
Vitamin B-6mg1.59
Folate, DFEµg527
Vitamin B-12µg0.18
Vitamin A, RAEµg1
Vitamin A, IUIU28
Vitamin E (alpha-tocopherol)mg0.22
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg1.3
Lipids
Fatty acids, total saturatedg0.2
Fatty acids, total monounsaturatedg0.24
Fatty acids, total polyunsaturatedg0.35
Cholesterolmg0
Other
Caffeinemg0
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 9. Granola bars (uncoated, nut and raisin) nutrition facts

NutrientUnitValue per 100 gbar (1 oz) 28 g
Approximates
Waterg6.11.71
Energykcal454127
Proteing82.24
Total lipid (fat)g20.45.71
Carbohydrate, by differenceg63.617.81
Fiber, total dietaryg5.61.6
Minerals
Calcium, Camg8424
Iron, Femg2.180.61
Magnesium, Mgmg9125
Phosphorus, Pmg24167
Potassium, Kmg392110
Sodium, Namg25471
Zinc, Znmg1.60.45
Vitamins
Vitamin C, total ascorbic acidmg00
Thiaminmg0.190.053
Riboflavinmg0.190.053
Niacinmg2.610.731
Vitamin B-6mg0.120.034
Folate, DFEµg308
Vitamin B-12µg0.240.07
Vitamin A, RAEµg21
Vitamin A, IUIU4111
Lipids
Fatty acids, total saturatedg9.542.671
Fatty acids, total monounsaturatedg4.221.182
Fatty acids, total polyunsaturatedg5.521.546
Cholesterolmg00
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 10. Granola bars (hard and peanut butter) nutrition facts

NutrientUnitValue per 100 goz 28.35 g bar 24 g
Approximates
Waterg2.30.650.55
Energykcal483137116
Proteing9.82.782.35
Total lipid (fat)g23.86.755.71
Carbohydrate, by differenceg62.317.6614.95
Fiber, total dietaryg2.90.80.7
Minerals
Calcium, Camg411210
Iron, Femg2.40.680.58
Magnesium, Mgmg551613
Phosphorus, Pmg1393933
Potassium, Kmg2918270
Sodium, Namg2838068
Zinc, Znmg1.250.350.3
Vitamins
Vitamin C, total ascorbic acidmg0.20.10
Thiaminmg0.210.060.05
Riboflavinmg0.090.0260.022
Niacinmg1.970.5580.473
Vitamin B-6mg0.0960.0270.023
Folate, DFEµg1854
Vitamin B-12µg000
Vitamin A, RAEµg100
Vitamin A, IUIU1654
Lipids
Fatty acids, total saturatedg3.20.9070.768
Fatty acids, total monounsaturatedg71.9851.68
Fatty acids, total polyunsaturatedg12.083.4252.899
Cholesterolmg000
[Source: United States Department of Agriculture Agricultural Research Service 1]

Table 11. Granola bars (coconut and chocolate coated) nutrition facts

NutrientUnitValue per 100 goz 28.35 g
Approximates
Waterg6.11.73
Energykcal531151
Proteing5.21.47
Total lipid (fat)g32.29.13
Carbohydrate, by differenceg55.215.65
Fiber, total dietaryg6.21.8
Sugars, totalg34.279.72
Minerals
Calcium, Camg4212
Iron, Femg1.750.5
Magnesium, Mgmg5616
Phosphorus, Pmg15444
Potassium, Kmg25472
Sodium, Namg15243
Zinc, Znmg1.170.33
Vitamins
Vitamin C, total ascorbic acidmg0.50.1
Thiaminmg0.140.04
Riboflavinmg0.080.023
Niacinmg0.420.119
Vitamin B-6mg0.120.034
Folate, DFEµg93
Vitamin B-12µg0.070.02
Vitamin A, RAEµg00
Vitamin A, IUIU00
Vitamin E (alpha-tocopherol)mg0.30.09
Vitamin D (D2 + D3)µg00
Vitamin DIU00
Vitamin K (phylloquinone)µg1.40.4
Lipids
Fatty acids, total saturatedg22.726.441
Fatty acids, total monounsaturatedg4.971.409
Fatty acids, total polyunsaturatedg3.10.879
Cholesterolmg00
Other
Caffeinemg31
[Source: United States Department of Agriculture Agricultural Research Service 1]

How to find the best granola bars

Read the Nutrition Labels on the granola bars packaging.

Nutrition labels can help you choose between granola bars and keep a check on the amount of granola you’re eating that are high in fat, salt and added sugars.

Most pre-packed foods have a nutrition label on the back or side of the packaging. These labels include information on energy in kilojoules (kJ) and kilocalories (kcal), usually referred to as calories.

They also include information on fat, saturates (saturated fat), carbohydrate, sugars, protein and salt. All nutrition information is provided per 100 grams and sometimes per portion of the food.

Supermarkets and food manufacturers now highlight the energy, fat, saturated fat, sugars and salt content on the front of the packaging, alongside the reference intake for each of these.

You can use nutrition labels to help you choose the best granola bar.

How do I know if granola or a granola bar is high in fat, saturated fat, sugar or salt ?

There are guidelines to tell you if a granola cereal or granola bar is high in fat, saturated fat, salt or sugar, or not. These are:

Total fat

  • High: more than 17.5g of fat per 100g
  • Low: 3g of fat or less per 100g

Saturated fat

  • High: more than 5g of saturated fat per 100g
  • Low: 1.5g of saturated fat or less per 100g

Sugars

  • High: more than 22.5g of total sugars per 100g
  • Moderate: between 5g to 22.5 g of total sugars per 100g
  • Low: 5g of total sugars or less per 100g

Salt

  • High: more than 1.5g of salt per 100g (or 0.6g sodium)
  • Low: 0.3g of salt or less per 100g (or 0.1g sodium)

For example, if you are trying to cut down on saturated fat, limit your consumption of foods that have more than 5g of saturated fat per 100g.

If you’re trying to cut down on sugar, you should avoid foods that have more than 22.5g of sugars per 100g.

Some nutrition labels on the back or side of packaging also provide information about reference intakes.

Sugar, fat and salt levels

You can use the per 100g information on the nutrition label to identify granola or granola bars that are:

High in sugar, fat or salt

  • high in sugar: more than 22.5g of total sugars per 100g
  • high in fat: more than 17.5g of fat per 100g
  • high in salt: more than 1.5g of salt per 100g

Low in sugar, fat or salt

  • low in sugar: 5g of total sugars or less per 100g
  • low in fat: 3g of saturated fat or less per 100g
  • low in salt: 0.3g of salt or less per 100g

Reference intakes explained

You’ll see reference intakes referred to on food labels. They show you the maximum amount of calories and nutrients you should eat in a day.

  • Nutrition labels can also provide information on how a particular food or drink product fits into your daily diet.
  • Reference intakes are guidelines about the approximate amount of particular nutrients and energy required for a healthy diet.

Daily reference intakes for the average adult aged 19 to 64 are:

  • Energy: 8,400 kJ/2,000kcal (for an average adult male)
  • Total fat: less than 70g
  • Saturates: less than 20g
  • Carbohydrate: at least 260g
  • Total sugars: 90g
  • Protein: 50g
  • Fiber: 35g
  • Salt: less than 2.3g

The reference intake for total sugars includes sugars from milk and fruit, as well as added sugar.

Reference intakes aren’t meant to be targets. They just give you a rough idea of how much energy you should be eating each day and how much fat, sugar, salt and so on.

Unless the label says otherwise, reference intakes are based on an average-sized adult doing an average amount of physical activity.

This is to reduce the risk of people with lower energy requirements eating too much, and to make sure information on labels is clear and consistent.

Where to find reference intakes on food packs

Most of the big supermarkets and many food manufacturers also display nutritional information on the front of pre-packed food. This is very useful when you want to compare different food products at a glance.

If you look closely at food packaging, you’ll see that it usually tells you what percentage of your daily reference intakes each portion of that food contains.

Front-of-pack labels, such as the label in the above image, usually give a quick guide to:

  • energy
  • fat content
  • saturated fat content
  • sugars content
  • salt content

These labels provide information on the number of grams of fat, saturated fat, sugars and salt, and the amount of energy (in kJ and kcal) in a serving or portion of the food.

  • But be aware that the manufacturer’s idea of a portion may be different from yours.

Some front-of-pack nutrition labels also provide information about reference intakes.

Color-coded nutritional information, as shown in Figure 2. below, tells you at a glance if the food has high, medium or low amounts of fat, saturated fat, sugars and salt.

  • Red means high
  • Amber means medium
  • Green means low

In short, the more green on the label, the healthier the choice. If you buy a food that has all or mostly green on the label, you know straight away that it’s a healthier choice.

Amber means neither high nor low, so you can eat foods with all or mostly amber on the label most of the time.

But any red on the label means the food is high in fat, saturated fat, salt or sugars, and these are the foods we should cut down on. Try to eat these foods less often and in small amounts.

Figure 1. Reference intakes on food packs 

reference intakes on food packs

For example, the label above, taken from a box of pizza, shows that per half (1/2) slice of pizza will provide you with 4.7g of sugars, which is 6% of your daily reference intake for sugars.

The red color shows you that the pizza are high in saturated fat and salt.

Each pizza also contains 10.3g of saturated fat, which is 52% of your reference intake for saturated fat.

The amber color tells you that the pizza slices contain a medium amount (20.3g per 100 g of pizza) of fat.

Green means a food is low in a particular nutrient. These pizza slices, for example, are low in added sugars.

Ingredients list

Most pre-packed food products also have a list of ingredients on the packaging or an attached label. The ingredients list can also help you work out how healthy the product is.

Ingredients are listed in order of weight, so the main ingredients in the packaged food always come first. That means that if the first few ingredients are high-fat ingredients, such as cream, butter or oil, then the food in question is a high-fat food.

Figure 2. Breakfast cereal ingredients list (Oatmeal Crisp cereal)

Breakfast cereal ingredients list

Is granola healthy?

The health benefits of granola in general depends on the amount of oats and whole grains in the granola breakfast cereal or granola bars in addition to the amount of added sugar (sugars content), fat (saturated fat content) and salt (salt content).Consumption of oats or oat based products by individuals with various metabolic disease risk factors (e.g., hypercholesterolemia, obesity, and diabetes) and in different ethnic groups, has been shown to mediate an appreciable normalization of plasma cholesterol levels 2. The cholesterol lowering activity of oats is usually attributed to its ability to reduce intestinal absorption of cholesterol and/or inhibit the enterohepatic circulation of bile acids by increasing carriage of cholesterol and/or bile acids into the colon and facilitating their excretion in feces 3. Whole grain oats contain a number of potentially bioactive components capable of modulating cholesterol metabolism in mammals, including unsaturated fatty acids, fibers, such as beta-glucan, arabinoxylans, arabinogalactans, and resistant starch. Some of these polysaccharides can form viscous gels in aqueous solutions, and/or directly bind cholesterol or bile acids, while all are fermentable by the gut microbiota into short chain fatty  acids (SCFA).

Oats, and whole grain oat Granola also contains polyphenolic compounds and phytoeostrogens which may also modulate the gut microbiota and impact on host metabolic parameters 4. However, it is the gel forming nature of beta-glucans which is most commonly attributed to the cholesterol lowering effect of oats. Tiwari and Cummins 5 performed a meta-analysis on 126 studies and concluded that there was a significant dose-dependent inverse relationship between beta-glucan from oats and barley and blood total cholesterol, LDL “bad” cholesterol, and triacylglycerol concentrations with 3 g/day beta-glucan being sufficient to lower blood total cholesterol by −0.30 mmol/L 5. There is significant body of evidence that ingestion of oats, and oat derived fractions, most notably, β-glucan, at 3 g/day, is associated with a significant reduction in blood total cholesterol and LDL “bad” cholesterol in hypercholesterolemic groups 6. Although, the bile acid and possibly cholesterol binding abilities of β-glucans have been suggested to be responsible for the hypocholesterolemic effects in vivo, other mechanisms may also be involved, including those linked to the human gut microbiota which have not been addressed to date. While the ability of oats and beta-glucans to increase excretion of bile acids and cholesterol in feces appears to be well established, the underlying mechanism still remains to be fully elucidated. Although the gel forming nature of beta-glucans reducing bile acid/cholesterol absorption is the most commonly proposed mechanism, recent studies with probiotic microorganisms raise the possibility of bile salt hydrolase activity as another possible mechanism by which oats and fermentable fibers can lower plasma cholesterol 7. Studies on non-gel forming prebiotic fibers, which modulate gut bacteria and increase bile salt hydrolase active lactobacilli and bifidobacteria, support the hypothesis that an increased bile salt hydrolase activity due to gut bacterial modulation could reduce plasma cholesterol 8.

What is the healthiest granola breakfast cereal

Try looking at the nutrition label and compare brands so you opt for the healthier version.

For a healthier option, choose granola breakfast cereals that contain wholegrains and are lower in sugar, fat and salt.

Whole grains consist of the intact, ground, cracked or flaked fruit of the grains where the primary components (bran, germ, endosperm) are retained within their natural ratio 9. The putative health enhancing properties of whole grains are attributed to the presence of nutrients and bioactive compounds which are mainly found in the bran and germ 10. Consistent observational evidence associates habitual consumption of wholegrain foods with a wide range of positive impacts on health such as a reduced risk of diabetes, obesity, cardiovascular disease and cancer 11.

Examples include:

  • Wholewheat cereal biscuits
  • Shredded wholegrain pillows
  • Oats
  • Barley

Table 12. Grains included in the HEALTHGRAIN whole grain definition

CerealScientific name
Cereals
 Wheat, including spelt, emmer, faro, einkorn, khorasan wheat1, durumsTriticum spp.
 Rice, including brown, black, red, and other coloured rice varietiesOryza spp.
 Barley, including hull-less or naked barley but not pearledHordeum spp.
 Maize (corn)Zea mays
 RyeSecale spp.
 Oats, including hull-less or naked oatsAvena spp.
 MilletsBrachiaria spp.; Pennisetum spp.; Panicum spp.; Setaria spp.; Paspalum spp.; Eleusine spp.; Echinochloa spp.
 SorghumSorghum spp.
 Teff (tef)Eragrotis spp.
 TriticaleTriticale
 Canary seedPhalaris canariensis*
 Job’s tearsCoizlacryma-jobi
 Fonio, black fonio, Asian milletDigitaria spp.
Pseudocereals
 AmaranthAmaranthus caudatus
 Buckwheat tartar buckwheatFagopyrum spp.
 QuinoaChenopodium quinoa Willd. is generally considered to be a single species within the Chenopodioideae
Wild rice**Zizania aquatica

Notes:

1Khorasan wheat – also known as Kamut (registered trademark).
*In the first version of the definition document two scientific names were erroneously mentioned: Phalaris arundinacea and P. canariensis. The former one is a noxious weed.
**In the first version, wild rice was – incorrectly – listed as a cereal and not as a pseudocereal.
[Source 12]

Wholegrains contain fiber and B vitamins, among other nutrients. Fiber helps keep your digestive systems healthy. Research suggests a diet high in fiber may help reduce the risk of developing heart disease and type 2 diabetes.

  • Avoid always going for the same brand, as manufacturers regularly modify their recipes.

Oats, barley, or psyllium-based cereals can help lower cholesterol concentrations (excellent evidence and can be trusted to guide practice), and high-fiber, wheat-based cereals can improve bowel function 13.

Serving cereal with milk or yogurt

Having breakfast cereal is a good opportunity to add calcium to the diet if you serve it with milk or yogurt. Go for semi-skimmed, 1% or skimmed milk, or lower-fat yogurt.

Milk and yogurt are good sources of calcium and protein. Alternatives to cow’s milk include fortified soya, rice and oat drinks.

Adding fruit to cereal

Having cereal is also a good opportunity to get some fruit in the diet. Raisins, dried apricots, bananas and strawberries are popular choices and can be added to any cereal, depending on your tastes.

Adding fruit to cereals is a great way to get kids to eat more fruit. It also helps them enjoy less sugary cereals, as you get sweetness from the fruit.

I don’t have time to sit down for breakfast

It’s a sign of the times that people are increasingly abandoning breakfast cereals, one of the earliest convenience foods, for more convenient “on-the-go” options, such as a breakfast muffin and a latte.

If you’re short on time in the morning, how about setting the table the night before ? You could also grab a pot of porridge on your way to work or have your cereal when you get in.

Cereals are still one of the best value breakfasts out there. A bowl of fortified breakfast cereal with milk gives you more nutrients for your penny when compared with most on-the-go breakfast options.

You could try:

  • Muesli, fresh fruit and low-fat yogurt – fruit added to your muesli counts towards your daily requirements. Low-fat yogurt provides calcium and protein, and is low in fat, but watch out for the sugar content. Go for muesli with no added sugar.
  • Porridge with mashed banana and dried blueberries – put oats and a handful of dried blueberries in a bowl and add semi-skimmed milk. Heat in the microwave for 3-4 minutes, stirring every so often. When cooked, stir in the mashed banana. The mashed banana is a healthier substitute for sugar or honey. For best results, use a very ripe banana.
  • Overnight oats – combine oats and apple juice and let it sit overnight in the fridge. In the morning, add low-fat yogurt, honey to taste, and fresh fruit such as berries.
  • Quick porridge – making porridge is easier than you think: combine 50g of rolled or instant oats with 200ml (or more for runny porridge) of semi-skimmed milk in a bowl and microwave on full power for two minutes. Top with dried fruit or nuts.
  • Baked beans (low sugar & low salt variety) on wholemeal toast – not only are they naturally low in fat, baked beans are also packed with fibre and protein, making them a vegetarian source of protein. Look out for reduced salt and sugar ranges.
  • Banana bagel sandwich – mash a ripe banana and serve it between two halves of a toasted (preferably wholemeal) bagel. Mashing instead of slicing the banana gives the filling a creamier texture, meaning you won’t need low-fat spread.
  • One-minute omelette – combine one beaten egg, a few spinach leaves and some chopped lean roast ham in a bowl. Microwave on full power for a minute or until the egg is set.
  • Baked eggs – put an egg (with yolk unbroken) and some crème fraîche in a ramekin. Put the ramekin in a baking dish and fill with hot tap water so it comes 3/4 of the way to the top of the ramekin. Bake for 15 minutes or until the egg yolk is set to your liking.
  1. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][][][][][][][][][][]
  2. Randomized controlled trial of oatmeal consumption versus noodle consumption on blood lipids of urban Chinese adults with hypercholesterolemia. Zhang J, Li L, Song P, Wang C, Man Q, Meng L, Cai J, Kurilich A. Nutr J. 2012 Aug 6; 11():54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489577/[]
  3. Whole grain cereals: functional components and health benefits. Borneo R, León AE. Food Funct. 2012 Feb; 3(2):110-9 http://pubs.rsc.org/en/Content/ArticleLanding/2012/FO/C1FO10165J#!divAbstract[]
  4. Bioactivity of oats as it relates to cardiovascular disease. Ryan D, Kendall M, Robards K. Nutr Res Rev. 2007 Dec; 20(2):147-62. https://www.ncbi.nlm.nih.gov/pubmed/19079867/[]
  5. Meta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels. Tiwari U, Cummins E. Nutrition. 2011 Oct; 27(10):1008-16. https://www.ncbi.nlm.nih.gov/pubmed/21470820/[][]
  6. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2010). Scientific Opinion on the substantiation of a health claim related to oat beta glucan and lowering blood cholesterol and reduced risk of (coronary) heart disease pursuant to Article 14 of Regulation (EC) No 1924/2006. EFSA J. 8:1885 10.2903/j.efsa.2010.1885[]
  7. Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. Jones ML, Martoni CJ, Prakash S. Eur J Clin Nutr. 2012 Nov; 66(11):1234-41. https://www.ncbi.nlm.nih.gov/pubmed/22990854/[]
  8. Purification and characterization of three different types of bile salt hydrolases from Bifidobacterium strains. Kim GB, Yi SH, Lee BH. J Dairy Sci. 2004 Feb; 87(2):258-66. https://www.ncbi.nlm.nih.gov/pubmed/14762068/[]
  9. The HEALTHGRAIN definition of ‘whole grain’. van der Kamp JW, Poutanen K, Seal CJ, Richardson DP. Food Nutr Res. 2014; 58 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915794/[]
  10. Slavin J., Tucker M., Harriman C., Jonnalagadda S.S. Whole grains: Definition, dietary recommendations, and health benefits. Cereal Foods World. 2013;58:191–198. doi: 10.1094/CFW-58-4-0191[]
  11. Whole-grain foods and chronic disease: evidence from epidemiological and intervention studies. Seal CJ, Brownlee IA. Proc Nutr Soc. 2015 Aug; 74(3):313-9. https://www.ncbi.nlm.nih.gov/pubmed/26062574/[]
  12. Van der Kamp JW, Poutanen K, Seal CJ, Richardson DP. The HEALTHGRAIN definition of “whole grain.” Food & Nutrition Research. 2014;58:10.3402/fnr.v58.22100. doi:10.3402/fnr.v58.22100. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915794/[]
  13. Williams PG. The Benefits of Breakfast Cereal Consumption: A Systematic Review of the Evidence Base. Advances in Nutrition. 2014;5(5):636S-673S. doi:10.3945/an.114.006247. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188247/[]
read more

Bulgur

bulgur

What is bulgur

When wheat (either Triticum aestivum vulgare, Triticum turgidum durum or Triticum spelta) kernels are cleaned, boiled (cooked), dried, dehulled, ground by a mill, optionally polished, then sorted by size, the result is bulgur 1. This wheat product is sometimes referred to as “Middle Eastern pasta” for its versatility as a base for all sorts of dishes. Bulgur is sometimes confused with cracked wheat, which is crushed wheat grain that has not been boiled (cooked). Instead, bulgur is cracked wheat that has been partially cooked. Bulgur is ranked among the most nutritious food resource by the American Science Center 1. Bulgur is an excellent food source due to its low cost, storability (long shelf-life), ease of preparation, and high nutritional value (see bulgur nutrition Tables 1 and 2 below), which resists mold contamination and attack by insects and mites 2. Bulgur is also stored for humans nutrition purposes in some countries because of its resistance to absorbance of radiation (bulgur is one of the important wheat products in the U.S.A., and it is included in the special list of food rations in nuclear fallout shelters, recently), prevent intestinal cancer risk and consumable alone due to its fiber content (formation of fibrous structure, lack of phytic acid due to the processing properties) and good nutritional composition 3. Bulgur production is 2.5 times greater than pasta and bulgur is consumed at 12 kg per person annually in Turkey (in the East and South Parts of Turkey, 25 kg/person; also, in Syria, Iraq, Iran, Israel, Lebanon, Arabia i.e. Middle East countries, 30–35 kg/person) 4. In addition, bulgur is produced in USA, France, Sweden, Greece, Syria and Lebanon. Bulgur is recognized as a whole grain by the United States Department of Agriculture.

Because bulgur has been precooked and dried, it needs to be boiled for only about 10 minutes to be ready to eat – about the same time as dry pasta. Or you can simply add boiling water or broth to bulgur (about 1 ¾ to 2 cups liquid per cup of bulgur) and let it soak for about 20-25 minutes in a covered pot. This makes bulgur an extremely nutritious fast food for quick side dishes, pilafs or salads. Perhaps bulgur’s best-known traditional use is in the minty grain and vegetable salad known as tabbouleh.

Visual appearance, especially color, is the most important characteristic of foods and determines the choice or rejection of the product by the consumer 5. Bright yellow color is an important demand by consumers for bulgur 6. Color of bulgur is mainly due to natural pigments (carotenoids) that are present at different levels in wheat. Therefore, bulgur producers try many ways to improve the attractiveness of bulgur. In order to improve the color of bulgur and meet the consumer demands, bulgur producers first tried to add some dyes even if they were not allowed. Nowadays, there is a tendency to use natural additives. In addition, in industry, a mechanical kneading operation (it is called as polishing in industry) was widely used after drying and tempering to improve the color of bulgur. Squeezing the bulgur to provide some friction energy after tempering (increasing moisture content to a certain level) the brightness/yellowness of bulgur during polishing operation. Tempering is an important unit operation which the moisture content of bulgur is increased. Spray tempering before the mechanical polishing operation is the current method used mostly in bulgur industry. In this method, water is directly sprayed onto bulgur. After water addition, bulgur samples are rested to absorb it for 25–30 min. For the effectiveness of polishing operation, tempering is vital for cereal products. The literature about the effects of tempering on the color of final product are scanty. Furthermore, the relationship between total carotenoid content of the bulgur and yellowness, no documentation has been found during the literature review.

Besides tempering, sun drying is an important operation in traditional bulgur production. Sun-light is used to decrease the moisture content from 45 to 10 % (w.b.) by spreading the bulgur onto a clear surface for 8–10 hours. Traditionally, this method is believed to increase the yellowness of bulgur. Sun drying has some disadvantages like; non-hygienic product, lack of control over sun, difficulties to control the operation parameters, uneven drying, loss of product and non-standardized product. Imre 7 and Hayta 8 stated that the open-air sun drying may cause quality degradation and pollution infestation of the product. However according to the industrial experiences, sun dried bulgur has better yellow color than artificially dried bulgur. There is no study available about the effects of sun drying or UV-light on color bulgur.

Bulgur uses

Bulgur can be used in pilafs, soups, bakery goods, or as stuffing. In breads, it adds a whole grain component. It is a main ingredient in tabbouleh salad and kibbeh. It is often a substitute for rice or couscous. In Indian and Pakistani cuisine, bulgur is used as a cereal often to make a porridge with milk and sugar or a savory porridge with vegetables and spices. In the United States, it is often used as a side dish, much like pasta or rice. In meals, bulgur is often mistaken for rice because it can be prepared in a similar manner, although it has a texture more like couscous than rice.

How to be sure you’re getting whole bulgur: Because bulgur is made by cooking the entire wheat kernel, drying it and chopping it in smaller pieces, it remains a whole grain.

What is bulgur wheat

Bulgur is not a variety of wheat, bulgur is actually a traditional way of processing wheat. To make bulgur, the wheat kernels are cooked, then dried, then broken up into smaller pieces.

Is bulgur wheat gluten free?

No. Bulgur wheat contains gluten.

Figure 1. Bulgur grain

bulgur grain

Figure 2. Triticum turgidum durum wheat (pasta wheat)

Triticum turgidum durum wheat

Figure 3. Triticum aestivum vulgare wheat (common wheat or bread wheat and it’s the wheat for most wheat-based foods)

Figure 4. Triticum spelta wheat (spelt is an ancient wheat)

Triticum spelta wheat

Figure 5. Whole grain

Whole grain

Bulgur nutrition

Bulgur is classified as a wholegrain and it is a good source of dietary fiber ~ 12.5 gram per 100 gram dry bulgur. In their natural state growing in the fields, whole grains are the entire seed of a plant. A grain is considered to be a whole grain as long as all three original parts — the bran, germ, and endosperm — are still present in the same proportions as when the grain was growing in the fields 9. Whole grains represent the intact, ground, cracked, or flaked kernel of grains for which the starchy endosperm, germ, and bran are found in the same relative portions as they exist in the intact grain even after separation and reconstitution of the grain 10. Whole grains provide both nutrients and non-nutrients, which confer numerous health benefits 11. Dietary fiber from whole grains, as part of an overall healthy diet, may help improve blood cholesterol levels, and lower risk of heart disease, stroke, obesity and type 2 diabetes 12. Dietary fiber can make you feel full, so you may eat fewer calories. Including bulgur or other whole grains in your diet plan may help you reach or manage a healthy weight. Whole grain intake is inversely associated with risk of type 2 diabetes, and this association is stronger for bran than for germ 12. Findings from prospective cohort studies consistently support increasing whole grain consumption for the prevention of type 2 diabetes.

The 2015–2020 Dietary Guidelines for Americans 10 recommend consuming at least half of the daily grain servings as whole grains to reduce chronic disease risk. Similarly, the World Cancer Research Fund and American Institute for Cancer Research cancer prevention guidelines recommend eating relatively unprocessed cereals with every meal and limiting the intake of refined starchy foods 13. Nevertheless, whole grain intakes fall short of dietary guidance. Data from a nationally representative sample suggest that less than 10% of American adults consume the recommended 3 or more whole-grain servings per day 14, with no significant increases in whole-grain intakes over the past 10 years 15.

Evidence on whole grains and cereal fiber has been previously reviewed in relation to obesity, type 2 diabetes, and cardiovascular disease 16. A recent review showed that high intakes of cereal fiber and whole grains had a protective impact on the risk of these chronic diseases 16. However, for cancer, previous reviews on the association between whole grains and risk of first incident cancer have been limited to evidence from case–control studies and do not report risk estimates for cereal fiber 17.

A review of case–control evidence suggests that whole grains protect against various cancers 18. Cancer is a major public health burden in the United States, with high prevalence and incidence rates 19. The World Cancer Research Fund and American Institute for Cancer Research claim that altering diet may play a pivotal role in reducing cancer incidence 13. A protective impact of whole grains on cancer risk is biologically plausible. Whole grains are a rich source of antioxidants, vitamins, trace minerals, phytate, phenolic acids, lignans, and phytoestrogens with anticarcinogenic properties. Whole grains are also a major source of fiber. Due to the hypothesized association between dietary fiber and cancer 20, it is important to consider whether cereal fiber alone or whole grains, as a collective package of measured and unmeasured dietary constituents, are associated with cancer risk. However, most of the studies that reported lack of an association evaluated whole grains and cereal fiber in relation to lymphoma, female, and prostate cancers as an outcome. In contrast, approximately half of the studies evaluating gastrointestinal cancers and the 2 studies on renal cell carcinoma and head and neck cancers were suggestive of a protective impact of whole grains and cereal fiber on cancer risk, but evidence was limited to draw firm conclusions 21. Currently, the American Institute for Cancer Research and the American Cancer Society cancer prevention guidelines recommend choosing whole grains instead of refined grains as part of a comprehensive lifestyle approach to reduce cancer incidence 22. Based on the results of this qualitative review 21, a potential protective impact of whole grains and cereal fiber is limited to certain types of cancer, including head and neck cancers, renal cell carcinoma, and gastrointestinal cancers, which collectively constitute approximately a quarter of incident cancers 23. These data provide further support for recommendations to increase consumption of whole grains including whole wheat, bulgur, whole oats, oatmeal, whole grain corn and popcorn, brown and wild rice, whole rye, whole grain barley, buckwheat, triticale, millet, quinoa, and sorghum 24. Therefore, at an individual and population level, the consumption of whole-grain foods should be encouraged, primarily due to their protective impact on cardiovascular disease and diabetes, but also due to their potential role in reducing risk of these cancers, especially among high-risk individuals.

Table 1. Bulgur wheat (dry) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg9
Energykcal342
EnergykJ1431
Proteing12.29
Total lipid (fat)g1.33
Ashg1.51
Carbohydrate, by differenceg75.87
Fiber, total dietaryg12.5
Sugars, totalg0.41
Minerals
Calcium, Camg35
Iron, Femg2.46
Magnesium, Mgmg164
Phosphorus, Pmg300
Potassium, Kmg410
Sodium, Namg17
Zinc, Znmg1.93
Copper, Cumg0.335
Manganese, Mnmg3.048
Selenium, Seµg2.3
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.232
Riboflavinmg0.115
Niacinmg5.114
Pantothenic acidmg1.045
Vitamin B-6mg0.342
Folate, totalµg27
Folic acidµg0
Folate, foodµg27
Folate, DFEµg27
Choline, totalmg28.1
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg0
Retinolµg0
Carotene, betaµg5
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU9
Lycopeneµg0
Lutein + zeaxanthinµg220
Vitamin E (alpha-tocopherol)mg0.06
Vitamin E, addedmg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg1.9
Lipids
Fatty acids, total saturatedg0.232
04:00:00g0
06:00:00g0
08:00:00g0.013
10:00:00g0
12:00:00g0
14:00:00g0.001
16:00:00g0.203
18:00:00g0.011
Fatty acids, total monounsaturatedg0.173
16:1 undifferentiatedg0.007
18:1 undifferentiatedg0.166
20:01:00g0
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg0.541
18:2 undifferentiatedg0.518
18:3 undifferentiatedg0.023
18:04:00g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Cholesterolmg0
Amino Acids
Tryptophang0.19
Threonineg0.354
Isoleucineg0.455
Leucineg0.83
Lysineg0.339
Methionineg0.19
Cystineg0.285
Phenylalanineg0.58
Tyrosineg0.358
Valineg0.554
Arginineg0.575
Histidineg0.285
Alanineg0.436
Aspartic acidg0.63
Glutamic acidg3.878
Glycineg0.495
Prolineg1.275
Serineg0.58
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
[Source: United States Department of Agriculture Agricultural Research Service 25]

Table 2. Bulgur wheat (cooked) nutrition facts

NutrientUnitValue per 100 g
Approximates
Waterg77.76
Energykcal83
EnergykJ347
Proteing3.08
Total lipid (fat)g0.24
Ashg0.34
Carbohydrate, by differenceg18.58
Fiber, total dietaryg4.5
Sugars, totalg0.1
Minerals
Calcium, Camg10
Iron, Femg0.96
Magnesium, Mgmg32
Phosphorus, Pmg40
Potassium, Kmg68
Sodium, Namg5
Zinc, Znmg0.57
Copper, Cumg0.075
Manganese, Mnmg0.609
Selenium, Seµg0.6
Vitamins
Vitamin C, total ascorbic acidmg0
Thiaminmg0.057
Riboflavinmg0.028
Niacinmg1
Pantothenic acidmg0.344
Vitamin B-6mg0.083
Folate, totalµg18
Folic acidµg0
Folate, foodµg18
Folate, DFEµg18
Choline, total 1mg6.9
Betaine 1mg83.4
Vitamin B-12µg0
Vitamin B-12, addedµg0
Vitamin A, RAEµg0
Retinolµg0
Carotene, betaµg1
Carotene, alphaµg0
Cryptoxanthin, betaµg0
Vitamin A, IUIU2
Lycopeneµg0
Lutein + zeaxanthinµg54
Vitamin E (alpha-tocopherol)mg0.01
Vitamin E, addedmg0
Vitamin D (D2 + D3)µg0
Vitamin DIU0
Vitamin K (phylloquinone)µg0.5
Lipids
Fatty acids, total saturatedg0.042
04:00:00g0
06:00:00g0
08:00:00g0.002
10:00:00g0
12:00:00g0
14:00:00g0
16:00:00g0.037
18:00:00g0.002
Fatty acids, total monounsaturatedg0.031
16:1 undifferentiatedg0.001
18:1 undifferentiatedg0.03
20:01:00g0
22:1 undifferentiatedg0
Fatty acids, total polyunsaturatedg0.098
18:2 undifferentiatedg0.094
18:3 undifferentiatedg0.004
18:04:00g0
20:4 undifferentiatedg0
20:5 n-3 (EPA)g0
22:5 n-3 (DPA)g0
22:6 n-3 (DHA)g0
Cholesterolmg0
Amino Acids
Tryptophang0.048
Threonineg0.089
Isoleucineg0.114
Leucineg0.208
Lysineg0.085
Methionineg0.048
Cystineg0.071
Phenylalanineg0.145
Tyrosineg0.09
Valineg0.139
Arginineg0.144
Histidineg0.071
Alanineg0.109
Aspartic acidg0.158
Glutamic acidg0.973
Glycineg0.124
Prolineg0.32
Serineg0.145
Other
Alcohol, ethylg0
Caffeinemg0
Theobrominemg0
[Source: United States Department of Agriculture Agricultural Research Service 25]
  1. Dönmez E, Salantur A, Yazar S, Akar T, Yildirim Y (2004) Ülkemizde bulgurun yeri ve bulgurluk çeşit geliştirme Tarla Bitkileri Merkez Araştırma Enstitüsü Dergisi[][]
  2. Bayram M (2000) Bulgur around the world. Cereal Foods World 45(2):80–82[]
  3. Balci F, Bayram M. Improving the color of bulgur: new industrial applications of tempering and UV/sun-light treatments. Journal of Food Science and Technology. 2015;52(9):5579-5589. doi:10.1007/s13197-014-1687-x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554624/[]
  4. Bayram M, Öner MD (2002) The new old wheat: convenience and nutrition driving demand for bulgur. World Grain 51–53[]
  5. Ponsano EHG, Pinto M, Garcia-Neto M, Lacava P. Performance and color of broilers fed diets containing Rhodocyclus gelatinosus biomass. Rev Bras Ciênc Avícola. 2004;6:237–242[]
  6. Bayram M. Modelling of cooking of wheat to produce bulgur. J Food Eng. 2005;71:179–186. doi: 10.1016/j.jfoodeng.2004.10.032.[]
  7. Imre L. Solar dryers industrial drying of foods. London: Blackie; 1997.[]
  8. Hayta M. Bulgur quality as affected by drying methods. J Food Sci. 2002;67:2241–2244. doi: 10.1111/j.1365-2621.2002.tb09534.x.[]
  9. Whole Grains Council. Whole Grains 101. https://wholegrainscouncil.org/whole-grains-101[]
  10. 2015–2020 Dietary Guidelines for Americans. https://health.gov/dietaryguidelines/2015/guidelines/[][]
  11. Consumption of cereal fiber, mixtures of whole grains and bran, and whole grains and risk reduction in type 2 diabetes, obesity, and cardiovascular disease. Cho SS, Qi L, Fahey GC Jr, Klurfeld DM. Am J Clin Nutr. 2013 Aug; 98(2):594-619. https://www.ncbi.nlm.nih.gov/pubmed/23803885/[]
  12. De Munter JSL, Hu FB, Spiegelman D, Franz M, van Dam RM. Whole Grain, Bran, and Germ Intake and Risk of Type 2 Diabetes: A Prospective Cohort Study and Systematic Review. Groop LC, ed. PLoS Medicine. 2007;4(8):e261. doi:10.1371/journal.pmed.0040261. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952203/[][]
  13. World Cancer Research Fund, American Institute for Cancer Research. Food, Nutrition, and Physical Activity and the Prevention of Cancer: a Global Perspective. Washington, DC: American Institute for Cancer Research; 2007.[][]
  14. Reicks M, Jonnalagadda S, Albertson AM, et al. Total dietary fiber intakes in the US population are related to whole grain consumption: results from the National Health and Nutrition Examination Survey 2009 to 2010. Nutr Res. 2014;34:226–234. https://www.sciencedirect.com/science/article/pii/S0271531714000050[]
  15. McGill CR, Devareddy L. Ten-year trends in fiber and whole grain intakes and food sources for the United States Population: National Health and Nutrition Examination Survey 2001–2010. Nutrients. 2015;7:1119–1130. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344579/[]
  16. Cho SS, Qi L, Fahey GC, Jr, et al. Consumption of cereal fiber, mixtures of whole grains and bran, and whole grains and risk reduction in type 2 diabetes, obesity, and cardiovascular disease. Am J Clin Nutr. 2013;98:594–619 https://www.ncbi.nlm.nih.gov/pubmed/23803885[][]
  17. Jacobs DR, Jr, Slavin J, Marquart L. Whole grain intake and cancer: a review of the literature. Nutr Cancer. 1995;24:221–229. https://www.ncbi.nlm.nih.gov/pubmed/8610041[]
  18. Jacobs DR, Jr, Marquart L, Slavin J, et al. Whole-grain intake and cancer: an expanded review and meta-analysis. Nutr Cancer. 1998;30:85–96 https://www.ncbi.nlm.nih.gov/pubmed/9589426[]
  19. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA: Cancer J Clin. 2015;65:5–29 https://www.ncbi.nlm.nih.gov/pubmed/25559415[]
  20. Aune D, Chan D, Greenwood D, et al. Dietary fiber and breast cancer risk: a systematic review and meta-analysis of prospective studies. Ann Oncol. 2012;23:1394–1402 https://www.ncbi.nlm.nih.gov/pubmed/22234738[]
  21. Makarem N, Nicholson JM, Bandera EV, McKeown NM, Parekh N. Consumption of whole grains and cereal fiber in relation to cancer risk: a systematic review of longitudinal studies. Nutrition Reviews. 2016;74(6):353-373. doi:10.1093/nutrit/nuw003. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892300/[][]
  22. Kushi LH, Doyle C, McCullough M, et al. American Cancer Society guidelines on nutrition and physical activity for cancer prevention. CA: Cancer J Clin. 2012;62:30–67 https://www.ncbi.nlm.nih.gov/pubmed/22237782[]
  23. (Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA: Cancer J Clin. 2015;65:5–29 https://www.ncbi.nlm.nih.gov/pubmed/25559415[]
  24. Dietary Guidelines for Americans. https://health.gov/dietaryguidelines/[]
  25. United States Department of Agriculture Agricultural Research Service. National Nutrient Database for Standard Reference Legacy Release. https://ndb.nal.usda.gov/ndb/search/list[][]
read more
Health Jade